Dr. Michael Grandner is back for a wide-ranging discussion on a ton of sleep topics, including why sleep doesn't get a ton of attention in med school, and a new study that explores the link between daytime sleepiness and suicide.
Dr. Jason Ellis is regarded as one of the heavyweights of sleep science, particularly when it comes to his work with Cognitive Behavioral Therapy for Insomnia, or CBT-I. In this episode, we talk about Jay's book, The One Week Insomnia Cure, and how a quick hit of CBT-I worked in 73% of patients with acute insomnia. It really is a fascinating and wide-ranging discussion that includes everything from melatonin to med school, and what "the system" can do to make things better. Some key takeaways: “I think that [the COVID-19 pandemic] is actually going to create a lot of opportunities for sleep and sleep funding in the future. In the general population at any given time point, a snapshot of how many people might have acute insomnia works out to about 8% of the population. When I’ve extrapolated the data from Italy and from China, it looks like it’s going to be about 45%. So we’re going to see a huge uptake in acute insomnia. And I think that that’s going to drive more funding in the future.” “There is actually one study which demonstrates that CBT-I does decrease the symptom profile of RLS/PLMD. Now, what that study showed was, it’s not as if it stops somebody from having those periodic limb movements. But what it does do is it keeps them asleep during that time. And so one of the things [CBT-I] does is it deepens sleep. And if you deepen sleep enough, even somebody who’s in chronic pain will wake up a lot less. That’s why we see CBT-I works quite nicely in lots of pain conditions. And this one study did demonstrate that although people would have those arousals, they wouldn’t be woken up by them. So CBT-I is an option.” “Certainly in the UK, the amount of teaching in the area of sleep is minimal. I think it works out something like seven minutes overall.” LINKAPALOOZA Jay's book, The One Week Insomnia Cure on Amazon Jay's study about quick-hit CBT-I and acute insomnia
Dr. Ryan Vandrey from Johns Hopkins University is one of the leading authorities on cannabis, CBD and their impact on sleep and insomnia. He joins Neil for an update on the science related to cannabinoids, and whether cannabis and CBD have a measurable, beneficial impact on sleep, or if the claims about their efficacy as treatments for insomnia are merely marketing hype. Among the key takeaways in this week's episode: "There is data to support that it'll help you get to sleep faster, and that's going to be specific to THC. That has not been demonstrated with CBD." "Cannabis and CBD are being extolled as cures for all kinds of stuff. So we have this interesting scenario where this is an industry born in the illicit drug use market - and it's become licit and legal, but it's not very tightly regulated. So people are making all kinds of claims and marketing and trying to get people to use it for anything and everything. There needs to be some level of skepticism with the claims. And as a scientist, I always say, "Show me the data." "The other thing that's really limited in understanding the effects of cannabis on sleep - especially as a treatment for sleep problems - is that most of the studies have been done have been on healthy individuals without sleep problems." Along with Ryan, Dr. Michael Grandner is back with the latest in sleep science. (And we follow up on a Twitter exchange that revealed a fun blast from Michael's past!) LINKAPALOOZA: Dr. Ryan Vandrey's bio on the Johns Hopkins website (with links to much of his work) Ryan's 2014 study on the intersection of sleep disorders, PTSD and substance abuse Our ranking of The All-Time 15 Best Songs About Sleep The study Michael refers to about a blood test for sleeplessness is here.
Did you know that The Snooze Button podcast is really just the research phase of a book, made public? Now, we're "leaking" the first three chapters of the manuscript, in audiobook form, read by the author - Neil Hedley. Additionally, Dr. Michael Grandner returns with another weekly update on the latest in sleep science. LINKAPALOOZA: Here's the link to the page to support The Snooze Button book project. Here's the first of the two studies Michael mentioned. Here's the second of the two studies Michael referred to.