Professor of Genomics, Physiology, and Biophysics, Director of the WorldQuant Initiative for Quantitative Prediction and Director of Genomics at Tempus Labs, co-Founder and Global Director at Biotia, and co-Founder and scientific director at Onegevity. Chris develops and deploys computational and experimental methodologies to identify the functional genetic elements of the human genome and metagenome. To do this, he and his team perform research in three principal areas: (1) molecular profiling in patients with extreme phenotypes, including brain malformations, aggressive cancers, and astronauts, (2) creating new biochemical and computational techniques in DNA/RNA sequencing and DNA/RNA base modifications, and (3) the development of bioinformatics models for systems biology and metagenomics. In the very long term, he believes these systems-based methods will enable an understanding of the functional elements of the human genome and embedded metagenome, such that we can begin to repair or re-engineer these genetic networks for ameliorating disease and lay the foundation to enable long-term human spaceflight.