Mustafa Sultan, MD
Big Picture MedicineEpisodes
Episodes of Big Picture Medicine
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Konstantin started Kaia Health after paying $50,000 to cure his back pain at an elite pain rehab centre. It worked. But it seemed stupid. Why did this need to cost $50,000?Kaia Health has since raised $125M and helped 625,000 users. 0:00 Th
Jon Ronson is one of the most interesting people alive today — period.He’s the author of the Men Who Stare at Goats, So You’ve Been Publicly Shamed and The Psychopath Test — which spent 10 weeks on the New York Times bestseller list.His two
Max Parmentier is the CEO of Birdie, a Series B AgeTech startup who have raised $52M from the likes of Sofina, Omers Ventures and Index Ventures — and captured 10% of the UK market whilst currently scaling into Europe.0:00 Intro2:37 Shopify v
Tom Wicher is CEO of DrDoctor — who have served over 20M patients and just raised £10M in their recent Series A round. But he spent the first 7 years bootstrapping, and diverged from his colleagues: Opting for the slow and steady gentle disrupt
Drug discovery is becoming more expensive and producing less results than ever before (Eroom's Law)—why?One of the ballooning costs are clinical trials. Pharma/biotech often outsource their trials to CROs (contract research organisations).B
Rewind.ai just raised their Series A at a valuation of $350M. Investors include Andreesen Horowitz, Reddit’s Alexis Ohanian and OpenAI’s Sam Altman.Rewind sits on your computer and phone, and watches everything you do. Then you can ask it q
People are wearing Apple Watches to their wedding days. Has this whole 'quantified self' movement gone bananas? Is any of this data actually useful?I spoke to Maitham Dib about this. He's building Vital (YC21); a startup which makes all weara
Dr Jared Dashevsky writes Healthcare Huddle (acquired by Workweek). He's scaled to over 30,000 subscribers. And it was pretty simple.Here are 12 frameworks that work for healthcare content creation (and mistakes to avoid).0:00 Intro1:14 Con
Despite $billions of investment into the sector — there are still no AI discovered drugs on the market. Why?Recursion Pharmaceuticals (NASDAQ: RXRX) is one of the hottest AI drug discovery companies on the market. Especially after NVIDIA's $5
0:00 NVIDIA's $50M investment into Recursion Pharmaceuticals2:28 NVIDIA is becoming a seed investor3:45 Bull case for Recursion Pharmaceuticals9:20 Recursion's two big acquisitions13:05 How are Recursion going to make money?14:15 Recursion
Ever waited months for a scan? Scan.com is making getting a scan as easy as booking an Uber. Behind the scenes of the disruptor changing medical imaging forever.0:00 Race to the bottom?1:34 AirBnB 11 star framework9:57 Scan.com looks really
0:00 David Sinclair's controversial claim 1:39 Bull v bear case6:23 David Sinclair's history of exaggerating and profiteering8:34 Adam Neuman's involvement11:40 Raising from unsophisticated investors16:30 Why aren't big pharma interested i
0:00 Why not let the builders build? Move fast and break things?1:56 Why don't you ban people from googling their symptoms?3:28 Is a disclaimer enough?5:27 Why are LLMs difficult to regulate?10:13 Move fast and kill patients — principal age
Daniel Ek (Spotify Founder) has raised $65M for his new longevity startup: Neko Health.0:00 What is Neko Health2:18 They're doing nothing new5:33 The bull case; why it's going to be huge7:47 How are they possibly going to make money!?18:3
0:00 Leaked secret Apple health report5:06 What Apple are up to in healthcare9:21 Decentralised clinical trials11:35 Apple healthcare leaked documents controversy15:38 Apple is going to become a health insurer23:07 Imran's advice to Tim Co
Huma is about to reach a 1 billion dollar valuation, and is thriving while other digital health companies are dying. But what’s their secret sauce? Dan Vahdat is the Johns Hopkins dropout — who meticulously studied the successful business pra
0:00 Intro1:04 The genius business model of GetHarley5:26 How important is marketing? 50% of revenue14:57 Why aren't they doing cooler more innovative stuff?22:38 What verticals would we expand GetHarley's biz model to24:37 Vitamin vs pain
0:00 Intro0:20 DEA comes after DTC health startups3:18 How DTC health startups hacked customer retention10:30 Will this kill the economics of D2C health startups?12:57 How would we solve the problem15:30 New LLM Paper in Nature28:18 Audie
Numan have raised $70M+ and are set to become the biggest men's digital health startup, ever. Here's how. From their eccentric Founder.0:00 Intro0:42 Valuation1:46 Lessons from Calm.com4:49 Raising aggressively 7:35 Successful entrepreneu
0:00 Intro0:18 Ali Parsa's Immigrant Story1:57 Picking a Problem That Was Too Big4:15 The Supply Induced Demand Problem5:55 The Unit Economics Problem7:37 The Misaligned Incentives Problem10:11 The Friction Problem12:06 The First Mover D
0:00 Intro0:38 VC Dirty Money (LP Sources)8:30 Power Dynamics Founder vs VC12:56 Trillion $ Alzheimer's Opportunity14:26 Eli Lily's New Alzheimer's Blockbuster (?) Donanemab19:01 More Issues with Donanemab Phase III Results21:48 Will Anyo
Papers Mentioned—ChatGPT better + more empathetic than human doctors (JAMA Int Med Paper): https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2804309Detecting eye disease using AI (Nature Biomedical Engineering): https://www.na
0:00 Intro0:32 Why are VCs so unhappy?2:18 What’s hard about being a VC?3:56 Hustle culture, FOMO, always-on culture in VC9:54 Is it ever easy to become rich?12:22 It’s time to build in healthcare15:31 Why is healthcare so hard for big te
Martin Shkreli is an American Investor, Pharmaceutical Executive and Hedge Fund Manager who became the most hated man in America in 2015 when he obtained the drug Daraprim and increased its price from $13.50 a pill, to $750 overnight.0:00 Int
Dr Ben Maruthappu is the the Co-founder and CEO of Cera Care; a digitally-enabled social care company which has raised over $400M dollars. He was made a Member of the Order of the British Empire in 2020.0:00 Intro0:47 Ben's story6:10 How to
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