On the Mayo Clinic Radio podcast, Dr. Robert Kraichely, a Mayo Clinic gastroenterologist, discusses treatment for irritable bowel syndrome. Also on the podcast, Dr. Jennifer Vande Voort, a Mayo Clinic psychiatrist, discusses esketamine nasal spray — a fast-acting treatment for depression that recently was approved by the Food and Drug Administration. And Dr. Nipunie Rajapakse, a Mayo Clinic infectious diseases specialist, share what you need to know about childhood vaccines.