Hi, I am Marmee Regine, your host in Pandemic Podcast Coronavirus. Today is the 10th episode where we will discuss the three types of coronavirus vaccine. They are the Pfizer/BioNTech, Moderna, and Astra Zeneca. These three vaccines currently passed the phase 3 clinical trials presently given as the emergency authorization vaccines. Every country already started injecting the vaccines, such as the UK, US, France, etc.
Introduction
The two vaccines, the Pfizer-BioNTech and the Moderna, are both mRNA vaccines. They are using new RNA technology. Now, what is mRNA, aka messenger RNA? In protein synthesis, the central dogma starts from DNA synthesis during transcription, followed by RNA synthesis during translation until the final protein product. In layman's terms, mRNA is a temporary transition state of cells until they are converted to protein in the cells' ribosomes.
Pfizer/BioNTech
To follow this process in the Pfizer-BioNTech, the vaccine itself contains mRNA that helps make the body's proteins. These proteins are responsible for eliciting an immunogenic response or immune responses that lead to antibodies' release to fight the infectious diseases invading the body. 
Moderna
In the Moderna vaccine depicts its vaccine, the messenger RNA is packaged in five prime regions, which keeps it from being broken down once it goes to the cell's cytoplasm to find its way to ribosomes. On the opposite side of the five prime regions is the three prime regions by the poly-A tail end; it does something similar, preventing the break down of mRNA so it will continue to be protein. Once this mRNA from the vaccine gets inside the cell, it will send a message to the immune system to work. Once the mRNA gets into our muscle cells and other essential cells that code for the spike protein, it will trigger the immune system. The protein synthesis in the ribosomes received the mRNA's message to rec

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