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Episode from the podcastPlanet B612

Gene editing with Olivier Belli

Released Tuesday, 25th May 2021
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PhD Student Olivier Belli joins me from Switzerland to talk about genetics and gene editing. We talk about the human genome, epigenetics, and CRISPR technology!

  • (0:00:35) A little background. 

  • (0:01:32) What is Molecular Biology?

  • (0:02:20) Gene editing and the academic path. 

  • (0:03:30) The Human Genome: Where we are. 

  • (0:04:33) The Human Genome: What is it?

  • (0:05:36) Epigenetics.

  • (0:08:10) Genetics: A young field.

  • (0:09:00) Classical genetics of the past vs the present approach.

  • (0:10:23) 23 and me: Genetics and our environment.

  • (0:13:11) The evolution of essential genes and their effects.

  • (0:14:59) Sickle cell disease and genetics.

  • (0:19:20) Correcting a mutation: Hemoglobin and genetics.

  • (0:20:30) What is CRISPR?

  • (0:23:17) CRISPR: Not a scary thing, just an easier one.

  • (0:25:05) The side effects of genetic modification: A work in progress. 

  • (0:26:00) Genetic Modification: A centuries old practice in agriculture.

  • (0:28:16) Cloning. 

  • (0:29:20) CRISPR and DNA breaks.

  • (0:31:46) Technology development in CRISPR: The study of disease mechanisms. 

  • (0:33:43) The study and work with the SARS-CoV-2 Virus.

  • (0:34:35) How viruses can infect and hijack our cells.

  • (0:36:35) The next five years: What's coming next?

  • (0:38:50) Ethical boundaries: Where do you draw the line?

  • (0:40:00) Embryo editing and eugenics: A Pandora's box.

  • (0:41:20) Science communication: Why it's so important.

  • (0:44:10) Politicizing science: Taking a stand in the public debate.

  • (0:45:30) Academics vs non-academics: The disconnect and how to solve it. 

  • (0:48:06) Music, Monoatomic God and playing the bass. 

  • (0:49:36) Science fiction and CRISPR.

  • (0:50:57) Alien DNA.

  • (0:52:13) Biology: Still so much to discover.

  • (0:53:32) Future plans.



Follow Olivier on Twitter: https://twitter.com/olivier_belli

Visit Planet B612 on the web: http://planetb612.fm/
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