Sigma Nutrition Radio

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In this episode Danny and Alan discuss the evidence for public health nutrition interventions, how health inequalities are driven by socioeconomic factors, and how ideology and simplistic rhetoric about "personal responsibility" can get in the way. Today's Topic in Focus [07:29] "I Have a Question!"  [82:22] Quack Asylum [85:20] Random Recommendations [91:14] Show notes available at
Alistair Monteyne is the lead author on some recent RCTs examining the impact of mycoprotein on muscle protein synthesis. Alistair is currently a PhD student in the Nutritional Physiology Research Group based at the University of Exeter in the UK. He also has a MSc. in Sport and Exercise Nutrition from Loughborough University.    Show notes available at
Dr Sarah Berry is a researcher and senior lecturer in nutritional science at King's College London. Her research interests relate to the influence of dietary components on markers of cardiovascular disease risk; with a particular focus on the influence of food and fat structure on postprandial metabolism. Dr. Berry has been the academic leader for more than 30 human nutrition studies in cardio-metabolic health. Her research also focuses on the influence of manipulation of food structure and subsequent effects on lipid and carbohydrate bioaccessibility and changes in postprandial metabolism. Sarah is also the lead nutritional scientist on an ongoing series of postprandial metabolic studies, assessing the genetic, metabolic, metagenomic, and meal-dependent effects on postprandial metabolic responses in >1,200 individuals in the UK and US. Show notes available at
Nick Hiebert writes about nutrition science on his site The Nutrivore, as well as exclusive, comprehnsive posts on his Patreon page. He is the creator of the "Nutrient Density Cheat Sheet", a nutrition ranking tool for hundreds of whole foods.  Nick has a deep interest in a host of nutrition science topics, from nutrient density to saturated fat & cardiovascular disease. He does a lot of deep analysis of raw data and has published some independent meta-analyses on his site.  Show notes can be found at
In this episode Danny and Alan discuss the common misunderstandings and misrepresentations of the energy balance equation, leading to problematic debates over the validity of 'calories in, calories out'.   Today's Topic in Focus: Calories In, Calories Out [02:15]    "I Have a Question!" [60:17]    Quack Asylum [70:20]    Random Recommendations [76:20]    SHOW NOTES:
In this episode Danny and Alan discuss the health impacts of coffee consumption, including long-term protective influence on disease risk, acute impacts, optimal dosages, genetic differences in metabolism and the influence of the bioactive compounds in coffee. Today's Topic in Focus: [01:50] "I Have a Question!" [68:18] Quack Asylum [71:03] Random Recommendations [81:50] Show Notes:
Dr. Nicky Keay is a medical doctor (MB BChir, MRCP) with specific training in endocrinology. She has published related to female athlete hormone profiling, energy availability, and relative energy deficiency in sport (RED-S). As a Research Fellow at St Thomas’ Hospital, she was part of the international medical team which developed an anti-doping test for growth hormone. Dr. Keay studied medicine at Cambridge University, gained membership of the Royal College of Physicians, and trained in endocrinology. Dr. Keay is currently an Honoray Fellow at Durham Universty in the Department of Sport and Exercise Sciences. Show notes at
Dr. Hana Kahleova is the director of clinical research at the Physicians Committee and directs research testing the effect a plant-based diet has on metabolism, insulin function, fitness, and mental health, as well as studying the impact meal timing and meal frequency have on metabolism and body weight.  Dr. Kahleova earned her doctorate in nutrition and diabetes and her medical degree from Charles University in Prague, Czech Republic. As a postdoctoral research fellow at Loma Linda University in California, Dr. Kahleova analyzed data from 50,000 Adventist Health Study-2 participants. She analyzed data on meal frequency and timing in relationship to changes in body weight.  Show notes at:
Danny & Alan discuss a recent paper on time-restricted eating that has been inaccurately interpreted by some as a "disproval" of TRE as an intervention. In this episode, the aim is to provide some context to the situation. There are also three listener questions, and another person/claim is brought into the quack asylum! Today's Topic in Focus: Time-Restricted Eating [05:14] "I Have a Question!" [57:27] Quack Asylum [73:35] Random Recommendations [86:05] SHOW NOTES:
Danny & Alan discuss issues with using and interpreting meta-analyses in nutritional science, they answer a question about methods of reheating food, and they highlight a recent paper published by quacks that experts have termed a "deception". Today's Topic in Focus [08:50] "I Have a Question!" [53:35] Quack Asylum [59:32] Something Random [66:42] Show notes:
Dr. James Hébert is a nutritional and cancer epidemiologist, currently a distinguished Professor at the University of South Carolina. Dr. Hébert’s professional focus for the past several years has been on developing and refining the Dietary Inflammatory Index™ (DII®), which has now been established as an effective research tool. Dr. Hébert is also a Professor in the Department of Epidemiology and Biostatistics, a Professor of Epidemiology at the Medical University of South Carolina, a Professor of Community Medicine and Epidemiology at the University of South Carolina, School of Medicine, and the Director of the Cancer Prevention and Control Program. Dr. Hébert obtained his ScD (Doctor of Science) in nutritional epidemiology from Harvard University in 1984. Show Notes:
Danny and Alan take a look at the evidence on weight loss maintenance, answer a question about ApoE4, and admit another nonsensical claim into the quack asylum. In this episode: [02:56] Today's Topic in Focus: Weight Regain vs Weight Loss Maintenance [58:56] I Have a Question!: "How does the ApoE4 allele affect lipid metabolism? And how should someone structure their diet around having one or both alleles due to it resulting in higher LDL-C than someone without the gene?" [63:09] Quack Asylum: Irish doctors gives nonsensical and harmful nutrition recommendations. [76:35] Random Recommendations Show notes:
Glenn Gibson is Professor of Food Microbiology at University of Reading. He has been researching bacteria in the gut for over 30 years. Together with his colleague Marcel B. Roberfroid, both researchers coined the term prebiotics in their 1995 paper. He has published over 450 research papers and 8 books. He currently researches acute and chronic gut disease, with specific projects on probiotics and prebiotics, gas production, gut microbiota development, gastroenteritis, obsesity and colonic homeostasis. Show Notes:
Dr Peter Olusoga is a Senior Lecturer in Psychology at Sheffield Hallam University. His current research focuses on stress, burnout and wellbeing in sports, with a particular interest in high-performance environments and elite coaching. Peter is a Chartered Psychologist with the British Psychological Society (BPS). Hugh Gilmore is an accredited sport psychologist with experience working in elite sport in the UK. Hugh has worked with elite athletes across a number of sports, including with the British Weightlifting team in the lead-up to the Olympic Games. Hugh has a MSc. in Applied Sport and Exercise Psychology. And is accredited by The Irish Institute of Sport and the British Association of Sport and Exercise Science (BASES). Peter and Hugh are the hosts of the new sport psychology podcast Eighty Percent Mental. Show Notes:
Professor Naomi Allen was appointed Chief Scientist for UK Biobank in 2019, having joined UK Biobank in November 2011 as Senior Epidemiologist. She is Professor of Epidemiology at the Nuffield Department of Population Health, University of Oxford, with a keen research interest in cancer epidemiology. At UK Biobank she is responsible for following-up participants both through linkage with routine health-related datasets, and through web-based questionnaires. She is also involved in developing the scientific strategy for future enhancements for the study. Her research interest is largely in the role of diet, obesity and circulating biomarkers in cancer development. Show Notes:
Today's Topic in Focus: Omega-3 Supplementation & Heart Disease [01:52]  "I Have a Question!" [66:30]: UK government obesity plan.  Quack Asylum [87:00]: Is a gram of PUFA in chicken worse than 250g of sugar from honey? Carnivore cannibalism!  Random Recommendations [94:20]  SHOW NOTES:
Alex Thomas is the founder of Sports Nutrition Association (SNA), which is global association that contains Sports Nutrition Australia, Sports Nutrition NewZealand, Sports Nutrition Asia, and Sports Nutrition USA. Alex is an experienced Clinical Accredited Sports Nutritionist. He is the Australasian Ambassador of the ISSN (International Society of Sports Nutrition). He is co-creator of the Metabolic Health Screen (A health risk and contraindication identification and triage system – now imbedded in the MyPocketcoach platform). His passion is in providing legitimate education, qualifications and insurance pathways to ensure the successful and sustainable career pathways for the profession of Sports Nutritionists. Alex believes we now have a unique opportunity to establish a significant meaningful impact and pride in what it is to hold the title of ‘Accredited Sports Nutritionist’ within the industry. Show notes:
Dr. Kathryn Bradbury, PhD is a researcher at the University of Auckland, New Zealand. Her research has focused on examining the role of diet in the development of cancer, cardiovascular disease and other non-communicable diseases. Dr. Bradbury spent 5 years in the Cancer Epidemiology Unit at the University of Oxford. There, she worked as a nutritional epidemiologist on large cohort studies, including the European Investigation into Cancer and Nutrition (EPIC), and the UK Biobank. She also has expertise in traditional and web-based dietary assessment methods, nutritional epidmiology (including prospective analyses of large cohort studies), biomarkers of nutritional status (including folate), blood lipids, the role of diet in the development of gastrointestinal cancers, and vegetarian nutrition. Show Notes:
Dr. Rebecca Leech is a Registered Nutritionist and Nutritional Epidemiologist, based at Deakin’s Institute for Physical Activity and Nutrition. Rebecca has a PhD in Nutritional Epidemiology, and in 2018, was awarded an Alfred Deakin Medal for her doctoral thesis, which examined adults’ eating patterns and their associations with diet quality and obesity. Her postdoctoral research, extends on this, and applies novel analytic approaches to understand determinants of food intake at eating occasions and the role of eating patterns in cardiometabolic health in adults. Dr. Leech is funded by an Alfred Deakin Postdoctoral Fellowship and received category 1 funding from the National Heart Foundation (NHF) Postdoctoral Fellowship in 2019. Show notes:
Prof. Martin Caraher is Emeritus Professor of food and health policy at Centre for Food Policy at City, University of London. He has worked for and acted as a consultant to the UK Department of Health, the World Bank and the World Health Organisation. He was a member of the original London Food Board which developed the food strategy for London. He is a member of the International Obesity Task Force (IOTF) scientific committee. He also sits on the Safefood Irl scientific committee. Show Notes:
Danny & Alan discuss how to understand causality in nutrition research. The episodes includes: inferring causality vs demonstrating causality, the hierarchy of evidence vs. standards of proof,  the erroneous application of the biomedical model to nutrition, RCTs vs. epidemiology, what the “highest quality evidence available” is, and how nutritional epidemiology can infer causality. Episode also includes a listener question, random recommendations and the Quack Asylum! Show notes:
In this episode Alan and Danny discuss the nutritional science research on vegan diets and human health. Some of the concepts covered include: defining “plant-based” diets, examination of various intervention trials comparing diets, veganism across the lifestage, benefits of a vegan diet, nutrient considerations and lots more. Show Notes:
Nanci Guest is a Registered Dietitian and has been working in this field in private practice since 1996. Dr. Guest completed has degrees in both Dietetics and Animal Science and dietetics, a masters degree in nutritional sciences, and a PhD nutrigenomics & athletic performance. She has published her research in top journals, presented many abstracts at international meetings and given dozens of invited talks in Canada, the USA and Europe. She has a special interest in plant-based diets, climate change, the environment and supporting animal welfare initiatives by helping individuals reduce their animal foods consumption. Show Notes:
Diana Rodgers and Robb Wolf are the co-authors of Sacred Cow, a book exploring the important role of animals in our food system. Diana is a Registered Dietitian living on a working organic farm in New England, where she runs an active nutrition practice. She speaks at universities and conferences internationally about nutrition and sustainability, social justice, animal welfare and food policy issues. She’s just completed work on the new book and film project, Sacred Cow. Robb Wolf is a former research biochemist and a New York Times/WSJ Best Selling author (for both The Paleo Solution and Wired To Eat). Robb has functioned as a review editor for the Journal of Nutrition and Metabolism (Biomed Central) and as a consultant for the Naval Special Warfare Resiliency program. Show notes:
Professor Corinna Hawkes has been working for the past 20 years with UN agencies, governments, NGOs and academia at the local, national and international level to support the design of more effective policies throughout the food system to improve diets and prevent malnutrition in all its forms. She is currently Director of the Centre for Food Policy at City, University of London, UK, a Centre dedicated to shaping a more effective food system through education, research and engagement with the world of food policy. In 2018 she was appointed Vice Chair of the London Child Obesity Taskforce by the Mayor of London. She was a member of the EAT-Lancet Commission on Healthy Diets from Sustainable Food Systems and the Lancet Commission on Obesity. Corinna has worked at the World Health Organization, the International Food Policy Research Institute, the University of Sao Paulo and as Head of Policy and Public Affairs at World Cancer Research Fund International, where she established the NOURISHING Framework which tracks policies to promote healthy eating worldwide. Show notes:
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Podcast Details

Created by
Danny Lennon
Podcast Status
Dec 1st, 2020
Latest Episode
Dec 1st, 2020
Release Period
Avg. Episode Length
About 1 hour

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