Two Scientists Walk Into a Bar
Two Scientists Walk Into a Bar
A monthly Science podcast featuring Jane Grogan
1 person rated this podcast
Two Scientists Walk Into a Bar
Two Scientists Walk Into a BarEpisodes
Two Scientists Walk Into a Bar
Two Scientists Walk Into a Bar
A monthly Science podcast featuring Jane Grogan
1 person rated this podcast
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Computational approaches have revolutionized how we interpret data. With the advent of genomic sequencing, scientists can derive significant conclusions from sequence data. For example, through transcriptomics – the study of genes and their exp
Join Danielle Mandikian and Maria Wilson as they kick off season five of Two Scientists Walk Into a Bar. Hear about their recent lab adventures and enjoy a sneak preview of exciting topics for our new season. From demystifying the impact of AI
When we consider how a vaccine works, we typically think about vaccines that prevent infectious disease like flu or measles. But another type, known as therapeutic vaccines, may be able to treat diseases even after they’ve taken hold in the bod
Because disease outcomes and responses to treatment can vary across populations, clinical research must include patients who are racially, ethnically and gender representative of those who experience health conditions. Scientists are pioneering
Achieving the first complete sequence of a human genome via the Human Genome Project represents an incredible feat – but it’s just the tip of the iceberg when it comes to unlocking the power of genomics for drug discovery and development. As th
Bacteria – and their constant ability to rapidly evolve and adapt – represent a scientific challenge that’s equal parts fascinating and disconcerting. The incredible innovations of the past century have not only prevented and treated infections
Understanding what happens in the brain is notoriously difficult, but scientists have made progress in the past few decades. For Alzheimer’s disease, scientists have expanded their knowledge of where and when certain proteins, cells and biologi
Taking a deep breath can seem like a simple process; however, for millions of people with asthma, inflammation of the airways could make it difficult to breathe. While current treatments help manage symptoms, scientists are working to develop n
Our understanding of what causes multiple sclerosis (MS) has transformed over the last few decades. While discoveries of the cell types involved in MS progression — both immune and brain — have led to major advancements for patients, there is s
Two Scientists Walk Into A Bar is back for a fourth season with new hosts, Maria Wilson and Danielle Mandikian! Get to know the new hosts and preview this season. Subscribe today so you don’t miss an episode!Read the full text transcript at h
Cells are the basic unit of life, with a remarkable ability to sense their environment, process information and adapt accordingly. With 37.2 trillion cells in the human body, there remains plenty for scientists to discover about how this sympho
The biological mysteries of age-related diseases have intrigued scientists for decades. In recent years, our expansive knowledge of genetics, thanks to the humble fruit fly, has opened our eyes to the mechanisms underlying these conditions. Now
In Season 1, we talked about using biomarkers and big data to match patients with the best treatment for their disease. In this episode, Jane sits down with David Shames, Senior Director of Cancer Immunotherapy Biomarkers and Staff Scientist in
Our eyes are our windows to the world, but what happens when those windows start to fade or disappear? To understand how the eye works, scientists are combining developments in imaging and genetics to see into the eye and better understand why
It’s easy to think of cancer as an invader to the body. But in reality, it’s simply the result of a few proofreading errors in DNA replication that occur over time when cells divide. In Episode 3, Jane Grogan chats with Fred de Sauvage, Vice Pr
Last episode, Jane and colleagues unraveled the intricacies of the human microbiome. This week, Jane chats with Mary Keir, Senior Scientist, Biomarker Discovery OMNI, to learn what happens during inflammatory bowel disease (IBD), what causes it
Our bodies are full of bacteria - pounds of them actually. We’re kicking off Season 3 with a closer look at the human microbiome and what happens when the synergistic relationship between our cells and our bacteria goes awry. Jane Grogan talks
Two Scientists Walk Into a Bar is back for a third season with host Jane Grogan chatting with scientists who are leading the charge to understand complex diseases. This season will tackle a range of new topics, including a deep dive into the hu
So far this season we’ve talked about the immune system a lot – how immune cells communicate, traffic along connective tissue, and invasive tumors. But what actually is the immune system? What’s it made of? How does it work? To close out our se
Pharmacology is the study of how a medicine works in the body, which is a critical step in understanding what medicines people should be given, and at what dose and schedule. As we learn more about the complex genomics that make each person uni
Neurons, the cells that make up our brain, are some of the most unique cells in our bodies. The complex nature of how they communicate leads to everything we say, think, or do. That complexity makes it hard to correct neural communication when
The lifecycle of a cell mirrors our own lives – cells live and die as we do. It would be easy to think of cell death, or apoptosis, as a negative action, but the death of a cell is actually critical to many of the important biological functions
Despite the best efforts of the human immune system, viruses and bacteria are constantly evolving to find new ways to breach our bodies’ natural defenses. Over the years, scientists have stepped in to develop novel ways to help the immune syste
Chemistry is all around us – from the air we breathe, to the food we eat, to the medicine we take when we’re sick. And for the researchers working to figure out how to make those medicines, chemistry can be an art as well as a science. Learn mo
The world of proteins is a minuscule and elegant ballet. Recent advances in imaging techniques have given us unprecedented views into this microscopic world, which could help us design better targeted therapies for a wide range of diseases. Lea
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