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We're two weeks into the 2022 NFL season, and already we have an idea of which teams might be headed for a serious title run -- none better than the dominant Buffalo Bills. Even so, upsets and comebacks are a weekly ingredient on the NFL schedule. So it's anyone's guess as to how Week 3 will unfold, especially with a handful of potential playoff previews on the docket.WATCH LIVE NOW:: https://directstream24.com/nflpro/WATCH LIVE NOW:: https://directstream24.com/nflpro/Thankfully, the experts at CBS Sports and SportsLine have you covered. Each week, we collect all of their best picks and betting advice in one place, so you can get picks against the spread from our experts as well as additional feature content for each game, including plays from top SportsLine experts and the SportsLine Projection Model, best bets from our staff, survivor picks and more.All NFL odds via Caesars Sportsbook.Which picks can you make with confidence in Week 3? And which Super Bowl contender goes down hard? Visit SportsLine, as its incredible model simulates every NFL game 10,000 times and is up more than $7,500 for $100 players on top-rated NFL picks since its inception.Houston Texans at Chicago BearsTime: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here) Open: Bears -2.5, O/U 39The Texans entered 2022 as a near-unanimous afterthought, but they've sniffed victory in each of their first two games, tying the Colts to open the season and then giving Russell Wilson and the Broncos a run for their money. Now, on the road against a Bears team fresh off a blowout loss to the Packers, they're positioned to get their first actual "W." Fantasy and gambling expert R.J. White has a pair of top-40 finishes in the Westgate Las Vegas SuperContest, the world's most prestigious handicapping tournament, and he likes Houston in this matchup.White, who's returned over $2,500 to $100 players since 2017 as SportsLine's top NFL expert in ATS picks, makes five total SuperContest picks each week. Check out all of them, with his analysis, right here.Las Vegas Raiders at Tennessee TitansTime: Sunday, 1 p.m. ET (Fox), stream on fuboTV (try for free)Open: Raiders -2, O/U 45.5This a game featuring two 0-2 teams that badly need a victory. The Titans are playing on a short week after getting blown out by the Bills on Monday night. But the Raiders are coming off a brutal loss where they blew a big lead. The Raiders will be able to move the ball through the air against a so-so Titans pass defense, which will allow them to pull out a close victory."CBS Sports senior NFL columnist Pete Prisco is taking the Raiders to get their first win of the 2022 season, albeit just barely. Check out his breakdown of every game in Week 3 right here.Kansas City Chiefs at Indianapolis ColtsTime: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here)Open: Chiefs -5.5, O/U 50.5"Of (this week's) seven potential teaser legs, one jumps out: Kansas City from -6.5 to -0.5 at Indianapolis. Patrick Mahomes has never lost a game indoors. While the 2-0 Chiefs have played to expectations, the 0-1-1 Colts are the league's biggest disappointment. This is obviously a desperation spot for the preseason AFC South favorites. It's the Colts' first home game. If they get Shaquille Leonard and Michael Pittman back, they could be competitive. I'll still take the Chiefs to win straight-up."Larry Hartstein, former lead writer for Covers and The Linemakers, is all over K.C. as part of his teaser picks for Week 3, when Indy will look to avoid an 0-3 start. Up more than 37 units on his NFL side picks for SportsLine entering 2022, he's got more analysis and other teaser selections right here.Buffalo Bills at Miami DolphinsTime: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here) Open: Bills -5, O/U 53"The Dolphins beat a Ravens team that had a bad defense and a Patriots team that had a bad offense, so what's going to happen when they play a Bills team that's not bad at either of those things? It's probably not going to end well for the Dolphins. The other problem is that they always seem to struggle against Josh Allen. The Bills have won seven straight games in this rivalry and those seven wins have come by an average of 19.3 points per game. Some quarterbacks just excel against certain teams. We've seen Aaron Rodgers dominate the Bears, Ben Roethlisberger dominate the Browns and Tom Brady dominate the Bills; now we're seeing Josh Allen dominate the Dolphins and I think that domination continues on Sunday."John Breech is on the Bills' bandwagon, projecting a 10-point win for Buffalo in Week 3. You can read all of his picks for this weekend's top games right here.Detroit Lions at Minnesota VikingsTime: Sunday, 1 p.m. ET (Fox), stream on fuboTV (try for free)Open: Vikings -6, O/U 52.5"The Lions over is a bet this season until it doesn't hit. This team simply refuses to die and thusly ends up in some kind of shootout every week. Imagine Dan Campbell yelling at you on the sideline -- you don't think about the scoreboard, you just feel like you shotgunned four Red Bulls in a row. Then you run on the field and pretend it's a one-score game."Will Brinson is buying into Detroit's ascent, so much so that he's picking the Lions not only to stay within a score but beat the Vikings outright on the road. He's also betting the over after an explosive two-week run from Jared Goff and Co. You can catch all of Brinson's Week 3 bets at CBS Sports right here.Baltimore Ravens at New England PatriotsTime: Sunday, 1 p.m. ET (Fox), stream on fuboTV (try for free)Open: Ravens -2.5, O/U 44The Patriots have had an ugly start to the 2022 season, barely edging the Steelers in Week 2 after falling to the Dolphins out of the gate. But SportsLine expert Larry Hartstein, who's up over $3,700 for $100 players all time, is trusting Bill Belichick as one of his Week 3 best bets for parlay picks: "It's the Patriots' home opener, and they're the far superior defensive team."If you successfully parlay Hartstein's Week 3 picks, you're looking at a payout of almost 6-1. Catch his full breakdown, as well as other picks for this weekend's games, right here.Two weeks into the season we still don't know anything. Well, I take that back -- I know my record against the spread currently isn't acceptable. We're going to work on that starting in Week 3, which profiles as a real interesting opportunity for some road teams with short numbers, either as a favorite or as a tiny dog. There's also a host of teams who are currently winless, and the heat is going to start getting turned up very quickly for anyone who heads into Week 4 without a single victory to their name. I think there's a decent chance one or two of them end up picking up that first win, including both the Bengals and the Texans. Let's get to the Week 3 picks. All NFL odds are via Caesars SportsbookNFL Week 3 PicksSteelers at BrownsThursday, 8:20 p.m. ETStream: Amazon PrimeFollow: CBS Sports App