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In this fourth installment of the CRISPR Chronicles, show hosts Fatu and Shekerah give  a review of sickle cell anemia, the cause and symptoms of the disease, and discuss how the CRISPR gene therapy treatment works.

Tune in to learn more about:

• The genetic basis of Sickle Cell Disease
• What Amazon delivery vans have in common with your Red Blood Cells
• The effect of mutant hemoglobin on Red Blood Cells
• The variety and severity of symptoms that SCD patients experience
• The disease burden of SCD throughout the world
• The clever strategy used to treat the disease with CRISPR gene therapy
• The results of the CRISPR Therapeutics and Vertex Pharmaceuticals gene therapy clinical trials
  
  For more information on this topic, visit our website: welovesciencepodcast.com
  
  

Hear directly from Sickle Cell Disease patients who received the treatment during the clinical trial: Victoria Gray and Jimi Olaghere

Catch up on the previous CRISPR episodes:

• Ep 35: The first CRISPR Chronicles episode: How CRISPR gene therapy is bringing hope to the world
• Ep 38: A foundational discussion explaining the secret behind CRISPR gene therapy 
• Ep 41: A look into the ups and downs of how the CRISPR saga developed

Reach out to Fatu:
www.linkedin.com/in/fatubm
Twitter: @thee_fatu_b
and [email protected]

Reach out to Shekerah:
www.linkedin.com/in/shekerah-primus
and [email protected]

Music from Pixabay: Future Artificial Intelligence Technology 130 by TimMoor
Music from https://freemusicarchive.org/music/Scott_Holmes: Hotshot by ScottHolmesMusic