Afif Safieh is a Palestinian diplomat. He has served as a Palestinian delegate to the Netherlands (1987–1990), to the United Kingdom (1990–2005), the Holy See, Vatican (1995–2005), and in Washington, D.C. as the head of the PLO mission (2005–2008). He was most recently the Palestinian ambassador to the Russian Federation. Safieh is an experienced diplomat, having served in the three most politically significant capitals: London, Washington, and Moscow. Before this, he was deputy director of the PLO Observer Mission to the United Nations Office at Geneva.