The research of Aadel A. Chaudhuri, M.D., Ph.D., is at the forefront of translational cancer genomics, with a particular emphasis on the development and application of liquid biopsy technologies. Dr. Chaudhuri's lab leverages cutting-edge technologies to conduct in-depth genomic analyses that are central to his research. These methodologies include: Enzymatic methyl sequencing for cell-free DNA epigenomic profiling. Whole-genome sequencing for copy number and fragmentomic analysis. Targeted deep sequencing to detect tumor-associated mutations. Deconvolution for analyzing the cellular composition of tumor samples. Developmental trajectory analysis to identify cancer stemness signatures. These advanced techniques enable comprehensive and precise analysis of tumor genomic data, forming the foundation of Dr. Chaudhuri's innovative research efforts. Dr. Chaudhuri's laboratory is funded by the National Cancer Institute (NCI), the National Institute of General Medical Sciences (NIGMS), the Children's Tumor Foundation (CTF), the Children's Discovery Institute, and the Melanoma Research Alliance. He also has successfully mentored M.D.-Ph.D., M.D., Ph.D. and postdoctoral trainees who went on to successfully obtain National Institutes of Health (NIH) and foundation award funding themselves, including NCI F30, NIGMS K08, CTF Young Investigator Award and Radiological Society of North America Medical Student Grant. Two of his former postdoctoral trainees are now fully independent assistant professors who lead their own academic research programs.