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Dr. David Koss

Dr. David Koss

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Dr. David Koss

Dr. David Koss

Research Associate at Newcastle University.David aims to understand the molecular pathology which underpins a range of neurodegenerative dementias. This principally involves the delineation of various cellular stress responses, the stimuli which activates them, how they interact with hallmark pathology and when in terms of disease progression, such responses become activated. Davis employs a variety of investigatory methods, including immuno-based assays and proteomics which he appliesy to post-mortem human tissue, but also cellular disease models. The aim of his work is to highlight pathological changes in stress pathways which are therapeutically exploitable and ultimately can be translated into improved clinical interventions. Whilst he primarily investigates Alzheimer’s disease and Lewy body dementia, he is keenly aware that on a mechanistic level there are points of commonality across the neurodegenerative spectrum. Accordingly, he feels that working to share the knowledge base acquired across the many associated diseases may help to establish an understanding of the detrimental pathways engaged within the aging brain.
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Creator Details

Location
Newcastle Upon Tyne, Tyne and Wear, England, United Kingdom
Episode Count
1
Podcast Count
1
Total Airtime
40m, 34s
PCID
Podchaser Creator ID logo 268817
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