Grisel is a behavioral neuroscientist with a particular interest in addiction. Her research attempts to identify psychological and genetic factors that lead some people to develop drug addictions while others in similar circumstances do not. Grisel’s work is inspired by her own personal experience with addiction, a struggle she chronicled in her book Never Enough, the Neuroscience and Experience of Addiction. The work, which appeared on the New York Times’ bestseller list for science books, established Grisel as a leading expert on the science of substance abuse. That reputation earned her an invitation to speak on addiction panels at the 2020 World Economic Forum.