Karla Fullner Satchell, Ph.D. is a professor of Microbiology and Immunology at Northwestern University, where she leads the Center for Structural Genomics of Infectious Diseases. Her research has focused on the role of secreted protein toxins on bacterial pathogenesis, the protein structure of Human Coronavirus, and she has been leading research into the treatment and vaccine of COVID-19.
All through the pandemic, we’ve been waiting for a possible silver bullet: a vaccine. How soon could we actually get one? To find out, we talk to microbiologist and immunologist Professor Karla Satchell, immunologist Dr. Kathryn Stephenson, Pfizer executive Mike McDermott, and Ian Haydon, who’s participating in a vaccine clinical trial.Here’s a link to our transcript: https://bit.ly/3egWFrcThis episode was produced by Wendy Zukerman, with help from Michelle Dang, Sinduja Srinivasan, Laura Morris, Meg Driscoll, Rose Rimler, Meryl Horn, and Mathilde Urfalino. We’re edited by Blythe Terrell with help from Caitlin Kenney. Fact checking by Lexi Krupp. Mix and sound design by Peter Leonard. Music written by Peter Leonard, Marcus Bagala, Emma Munger, and Bobby Lord. A huge thanks to all the researchers we got in touch with for this episode, including Dr. Barney Graham, Dr. Melvin Sanicas, Dr. Norbert Pardi, Professor Peter Waterhouse, Professor Edward Mocarski, Dr. Ramin Herati, Dr. Rachel Roper, and Dr. Yvonne Genzel. And special thanks to the Zukerman family and Joseph Lavelle Wilson.
President Trump says an anti-malarial drug could be a “gift from god” for treating Covid-19. Does it really work? And is it dangerous? We talk to toxicologist Professor Daniel Brooks, infectious disease specialist Dr. Matthew Pullen, and microbiologist Professor Karla Satchell. Also: VAMPIRE BATS!We’ve set up a voicemail to collect all of your questions about Coronavirus. Or if you’re a healthcare worker with a personal story you want to share, please call ‪(774) 481-1238‬ and leave us a message.Here’s a link to our transcript: https://bit.ly/2xu4ER8This episode was produced by Meryl Horn, Wendy Zukerman, Rose Rimler, Michelle Dang, Laura Morris, Meg Driscoll and Sinduja Srinivasan. We’re edited by Blythe Terrell and Caitlin Kenney. Fact checking by Eva Dasher. Mix and sound design by Peter Leonard. Music written by Peter Leonard, Emma Munger, and Bobby Lord. Thanks to the NBC News Archives. A big thanks to all the researchers that we got in touch with for this episode, including Professor Thomas Doerner, Dr Hue, Professor David Boulware, Dr. Anne Melzer. And special thanks to the Zukerman family and Joseph Lavelle Wilson.
Microbiologist Karla Satchell, PhD, is leading a national effort to investigate the structure biology of the components of the new coronavirus virus (2019-nCoV) and ultimately understand how to stop it from replicating in human cells through a medication or vaccine. This work is being done with the Center for Structural Genomics of Infectious Diseases at Northwestern, which is funded by the National Institute for Allergy and Infectious Diseases.  
Summer brings warm beach weather, and with it come gruesome news reports of “flesh eating disease” that people catch from the ocean. Vibrio vulnificus is a marine bacterium that prefers warmer seawater, and it can infect wounds and cause necrotizing fasciitis, also known as “flesh eating disease”, that can rapidly turn into a fatal infection. Dr. Karla Satchell is a professor at the Feinberg School of Medicine at Northwestern University who studies the toxins made by V. vulnificus and other Vibrios that allow them to cause disease. Satchell talks about how people get infected with V. vulnificus, who is most at risk for catching flesh eating disease, how global warming is increasing V. vulnificus infections, how MARTX and other toxins help V. vulnificus cause disease, why oysters are a source of V. vulnificus, and how a scientist from Oklahoma sparked her interest in research. microTalk was joined in this discussion by Karla’s son Grant Satchell. The microCase for listeners to solve is about Wolf Burns, a celebrity survival expert who comes down with a potentially fatal disease while trying to make his way out of the Ozark Mountain wilderness. Participants: Karl Klose, Ph.D. (UTSA) Karla Satchell, Ph.D. (Northwestern University) Grant Satchell Janakiram Seshu, Ph.D. (UTSA) Mylea Echazarreta (UTSA)  
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Creator Details

Episode Count
4
Podcast Count
3
Total Airtime
2 hours, 17 minutes