Patty Prewitt is an American woman whose case gained national attention after she was convicted in 1986 of murdering her husband, William Prewitt, in Holden, Missouri, a crime for which she has consistently maintained her innocence. A mother of five, she was sentenced to life in prison without parole for 50 years and has since become a figure of advocacy and debate, with legal experts, journalists, and supporters questioning the fairness of her trial and the handling of evidence. Over the decades, her story has been featured in national media outlets and true-crime programs, highlighting broader discussions about the justice system and wrongful convictions.