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a16z

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kaveinthran

Created April 30, 2020

Updated November 15, 2021

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  1. In this wide-ranging conversation about 'stuff' that took place at a16z's most recent annual investor meeting (VCs have investors too, in the form of 'limited partners'), Fortune's Dan Primack interviews Marc Andreessen -- and asks the tough qu
  2. Infrastructure. It powers everything from cities to computing, yet is sometimes considered "boring" because it is so invisible to so many of us. But as software continues to eat the world, infrastructure has come to the forefront. And some of t
  3. When the iPad first came out in 2010 there was chatter that went in two directions: 1. It’s just a big iPhone2. I’ll never carry a laptop againBoth were wrong. The big iPhone comment was quickly dispelled as people (and their kids) fell un
  4. Love the term or hate it, the concept and reality of the "sharing economy" (or "gig economy" and so on) is here to stay. And in fact, argues NYU Stern professor and researcher Arun Sundararajan, it may even reduce the income distribution gap be
  5. with Fei-Fei Li (@drfeifei), Frank Chen (@withfries2), and Sonal Chokshi (@smc90)Who has the advantage in artificial intelligence — big companies, startups, or academia? Perhaps all three, especially as they work together when it comes to fi
  6. Seemingly overnight, a single game -- Pokémon Go -- has taken people by storm. But it's a game that was technically years in the making, building on a legacy of creative intellectual property and technologies such as mobile, geomapping/ geoloca
  7. From hardware and hardwires to smartphones and social, technology wants to connect. It's almost a native property of technology and especially software businesses, which is why network effects matter. "It was endemic to these technologies that
  8. Bitcoin quickly made its way from a whitepaper to a production network, which is pretty amazing when you think about it. But its scripting/ programming language was initially, intentionally, limited for a few reasons, which meant that building
  9. "Incremental change may be good theory, but in practice you have to have a big enough stick to hit everybody with to make everything move at once". So shares Adrian Cockcroft, who helped lead Netflix's migration from datacenter to the cloud --
  10. From the silver age of on-prem software companies like SAP and Siebel Systems to the golden age of enterprise software-as-a-service, we're now seeing an explosion of data. All types, all sizes, and all over the place. And much of it is a sort o
  11. The most recent Oculus Connect event (the third and largest yet) has been lauded as bringing us closer than ever to the future promised for virtual reality or VR. There have been many hardware moves by many players, both recently and over the p
  12. "We live in a world where we use millions of variables to predict which ad you're going to click on. Whether or not you deserve to get a loan. What movie you might watch next. But when it comes to our bodies and even serious diseases, we want t
  13. Clearly disruption plays out not just in business but also in politics. Whether it was the Scottish national party, recent election campaigns, or local school boards, people grew and organized communities online all last year through NationBuil
  14. "We throw around words like 'crisis' very easily, but this is a global crisis, and it is of historic proportions," says current U.S. Deputy Secretary of State Tony Blinken about the refugee crisis (for which he and his department mobilized a re
  15. As people live longer, aging is more top of mind than ever. This is especially true for the "sandwich generation" wedged between caring for aging parents as well as young children at the same time.The fact is, the 65+ year old population (but
  16. As companies expand out from the internet into the rest of the economy — the proverbial bits to atoms — “the business models are becoming more complicated, more interesting, more payment based”, observes Patrick Collison, CEO and co-founder of
  17. What (on earth) does it take to get a signal to Pluto? Stanford senior scientist and astronomer Ivan Linscott, part of the team that ran the radio science experiment on the New Horizons probe, shares in conversation with a16z's Frank Chen all t
  18. From the significance of Google DeepMind's AlphaGo wins to recent advances in "expert-level artificial intelligence" in playing an imperfect/ asymmetric information game like poker, toys and games have played and continue to play a critical rol
  19. The largest asset class in the United States is owner-occupied real estate, yet options for homeowners accessing this are very binary right now: either own 100% of your home (with a mortgage), or own nothing. And when people do “own”, that owne
  20. "Mobile-first" (and now too AI-first) has been a mantra of sorts in design, but what does that mean at a company, product management, and competitive level? Especially when someone in company X will always say "we should do what Y did" -- even
  21. How to think about tech policy and top-of-mind issues for the tech industry, given a new president? From what agencies matter for different tech domains -- e.g., autonomous cars, drones, fintech, healthcare -- to recent staffing moves, the a16z
  22. How to think about business policy and top-of-mind issues for the tech industry, given a new president? From what agencies matter for startups and VC to what the first 100 days (and next two years!) look like, a16z managing partner Scott Kupor
  23. The building blocks for VR and AR are finally here -- but the content is just beginning. So everything you'll actually experience and consume in these new mediums over the next few years is being built right now. Formats aren't yet defined or l
  24. "Punch above your weight" -- If there's one thing public relations (PR) should help startups and founders do, it's that. Unfortunately, some companies are actually punching below their weight when there's a strong company, founder, product ...
  25. Once upon a time, Robert Stromberg got a phone call from "Jim" Cameron (aka James Francis Cameron of Terminator and Titanic fame) about a little project called Avatar. Before he knew it, he was responsible for designing the organic world of Pan
  26. In the age of the internet -- where information is freely available online, and connections between sellers and buyers of software products are visible on LinkedIn -- do analysts really matter? Do they play a role in decision-making for purchas
  27. Thanks to freeways, cities became something to get through instead of something to get to. Now, as the next transportation revolution -- from rivers to trains to cars to autonomous cars -- promises to change the face of our cities, what happens
  28. The modern enterprise holds all sorts of applications, devices, and workflow needs. How should we be thinking about securing infrastructure -- and identity -- in this context, for entities like major news media outlets or financial institutions
  29. The hardest thing about pivots (major shifts in company/product direction) isn't just the actual pivot. It's the courage to make the decision... and being honest with yourself as a CEO. Especially since, no matter how great the team or board or
  30. It's been nearly 15 years since the Human Genome Project was completed. But "are we there yet" in the golden age of genomics? What did we think we'd have by now, what do we actually have, and what do we really still need to make genomics live u
  31. Evolution and technology have allowed our human species to manipulate the physical environment around us -- reshaping fields into cities, redirecting rivers to irrigate farms, domesticating wild animals into captive food sources, conquering dis
  32. Imagine, for a moment, an alternative universe: One where Netflix got disrupted by some other streaming-content company that made its DVD rental business irrelevant. But that's just a counterfactual. What happened instead is that Netflix cannib
  33. Humans have always wanted to enhance themselves -- from getting nutrition just-right to optimizing their performance, whether in sports or health or work. And food is a big part of all that.But our current systems of food production (and consu
  34. The irony of our systems working so well -- technological, corporate, and yes, even political -- is that we've become too comfortable: matching to others just like us, producing less, taking fewer risks. But isn't the very point of technology t
  35. In this episode of the a16z Podcast introduced by Vijay Pande (based on a presentation at our summit event), Russ Altman, Stanford professor of bioengineering -- and former chairman of their Bioengineering Department -- takes us on a short but
  36. Starbucks supposedly spends more on healthcare than it does on coffee beans. And 20 years ago, says Rajeev Singh, CEO of Accolade, healthcare was 10% of GDP; today it’s 19% -- that's nearly one-fifths of our gross domestic product. So what tool
  37. Your brand, says head of a16z marketing and Outcast Agency co-founder Margit Wennmachers, is what people say about you when you're not in the room. And it's going to happen, whether you choose to have an active part in it or not. But what does
  38. A lot of machine learning startups initially feel a bit of “impostor syndrome” around competing with big companies, because (the argument goes), those companies have all the data; surely we can’t beat that! Yet there are many ways startups can,
  39. As we enter a new era of distributed computing -- and of big data, in the form of machine and deep learning -- storage becomes (even more) important. It might not be sexy, but storage is what makes the internet and cloud computing go round and
  40. An aerospace engineer who worked for NASA for over 40 years, Dr. Christine Darden is one of the mathematicians that the book and movie Hidden Figures was based on. Darden eventually would lead the sonic boom team, going on to become the first A
  41. In this episode of the a16z Podcast recorded at our inaugural Summit, Jonathan Downey, CEO of Airware, Grant Jordan, CEO of Skysafe, and Kyle Russell, partner at a16z, discuss our future with “eyes in the sky.”How do you balance experimentatio
  42. Most of us have probably heard of bitcoin and ethereum -- but did you know there were 15 new cryptocurrencies launched this past month alone? How then do we know which protocols to invest in -- not just as a developer or user, but as an investo
  43. The culture of open source has changed across generations, from previous ones that had to fight for the brave new way -- to the current "GitHub generation" that not only accepts open source, but expects it as the default. Which makes sense give
  44. Here’s what we know about open source: Developers are the new buyers. Community matters. And there will never be another Red Hat (i.e., a successful “open core” business model … nor do we necessarily think there should be).Yet open source is r
  45. A crisis is an opportunity to change one's culture, to model scenarios and set up a crisis plan/process, to become a better company. But it's also a bit like therapy, from the act of asking probing questions to get at the facts ... to dealing w
  46. Is it real or science fiction to dream of being able to treat… getting old? In this episode, we discuss with Dr. Thomas Rando from Stanford (who directs the Glenn Center for the Biology of Aging), Kristen Fortney, CEO of BioAge, and a16z’s gene
  47. In this hallway-style episode of the podcast, a16z partners Connie Chan and Kyle Russell discuss recent announcements at Facebook's annual developer conference, F8, in the context of trends such as: messaging and QR codes; brain computer interf
  48. The first thing that comes to mind when treating health problems is the need to take a pill (or other pharmaceutical) of some kind. But could a digital therapeutic -- a software-based intervention -- not only complement, but possibly even repla
  49. It’s the end of the beginning — not the beginning of the end — for wearables, argue the guests in this episode of the a16z Podcast. Especially as we move from the first, to the next, generation of wearable devices: not just activity trackers an
  50. A board veteran who has sat on both sides of the table, CEO of PagerDuty Jennifer Tejada shares what you gain from board membership (vs. being only an operator). How does being a board member change you as a CEO, and vice versa?Recorded as par
  51. Moore's Law -- putting more and more transistors on a chip -- accelerated the computing industry by so many orders of magnitude, it has (and continues to) achieve seemingly impossible feats. However, we're now resorting to brute-force hacks to
  52. In this lively conversation -- from our recent annual tech and policy summit in Washington, D.C. -- Axios' Dan Primack interviews a16z co-founder Marc Andreessen about the two major narratives dominating discussions about the tech industry righ
  53. When it comes to spycraft — or rather, “tradecraft,” as they say in the biz — what do the movies get right, and what do they get wrong? In this episode of the a16z Podcast, Michael Morell — former Deputy Director and twice-Acting Director of th
  54. There’s an interesting paradox when it comes to the U.S. government and tech: Either they’re an inventor, early adopter, and buyer of emerging new tech … or they’re a very late adopter (as in the case of government officials using Blackberries
  55. Discussions and headlines around tech policy tend to be dominated by what the President and the White House (aka the executive branch of the government) and what the Senate and House of Representatives (aka the legislative branch) are saying an
  56. Turnabout is fair play: That's true in politics, and it's true at Andreessen Horowitz given our internal (and very opinionated!) culture of debate -- where we often agree to disagree, or more often, disagree to agree. So in this special "turnab
  57. There's feedback and there's guidance; there's praise and there's criticism. All of it is important to do better work, but to develop a better and more productive workplace and relationships -- especially given how much time we spend at work! -
  58. Every industry (for-profit, non-profit, government, private-sector) has been touched by tech, with most trying to lead the charge in order to stay ahead. But museums and memorials, by definition, lag rather than lead there. How is that changing
  59. When people think of modernizing government, they tend to think of new IT, of improved procurement, of new infrastructure ... rather than social services like foster care or food stamps. But how can we actually help improve daily lives -- less
  60. "Slow down, cowboys" -- that's what Senator Kamala Harris (D-California) said when prosecutors in her office wanted to bring a case against companies that let apps download someone's entire address book, because surely that's a complete violati
  61. When individuals gain the abilities that only nation states once had, how do we put cyber threats in perspective for policymakers -- without unduly "inflating" the threats? As it is, security is an intense and important topic, so our job is to
  62. Nearly every cybersecurity discussion/presentation follows this formula: We don’t know what we’re doing; the bad guys are getting smarter; our defenses are getting worse; everything's more connected than ever; we’re heading towards a digital .
  63. "We're always fighting the last war" -- that's a phrase historians like to use because policymakers and others tend to be so focused on the threats they already know, and our mindsets and organizational structures are oriented to respond that w
  64. What is lobbying, really? Is it “white", "heavy-set" men "playing golf" and making arrangements in "smoke-filled back rooms”? It's not like that anymore, according to two lobbyists who join this episode of the a16z Podcast to pull back the curt
  65. Is a network -- whether a crowd or blockchain-based entity -- going to replace the firm anytime soon? Not yet, argue Andrew McAfee and Erik Brynjolfsson in the new book Machine, Platform, Crowd. But that title is a bit misleading, because the r
  66. A funny thing happened on the way to quantum computing: Unlike other major shifts in classic computing before it, it begins -- not ends -- with The Cloud. That's because quantum computers today are more like "physics experiments in a can" that
  67. This episode of the a16z Podcast takes us on a quick tour through the themes of economics/historian/journalist Marc Levinson's books -- from An Extraordinary Time, on the end of the postwar boom and the return of the ordinary economy; to The Gr
  68. In the age of virality, what does it actually mean to be popular? When does popularity -- or good product design, for that matter -- cross over from desire and engagement... to addiction? Journalist and editor Derek Thompson, author of Hit Make
  69. Here’s what we know: There’s a pair (father and son) of Russian scientists trying to resurrect (or rather, "rewild") an Ice Age (aka Pleistocene era) biome (grassland) complete with (gene edited, lab-grown) woolly mammoths (derived from elephan
  70. There are the things that you carefully plan when it comes to an IPO -- the who (the bankers, the desired institutional investors); the what (the pricing, the allocations); and the when (are we ready? is this a good public business?). But then
  71. with Jimmy Soni, Rob Goodman, and Steven SinofskyModern technology owes much to the introduction of the binary digit or "bit", first proposed by Claude Shannon in "A Mathematical Theory of Communication”, a paper published in 1948. The bit wou
  72. with Anne Mitchell, Lars Dalgaard, and Scott Kupor"Orthogonal thinking" but "shared core values" -- that's what makes an ideal board... especially when it comes to "independents", i.e., board members who aren't also investors. But how do you ge
  73. What happens when companies grow exponentially in a short amount of time -- to their organization, their product planning, their behavior towards change itself? In this "hallway conversation", a16z partners Steven Sinofsky and Benedict Evans di
  74. with Graham Allison and Matthew Colford"When a rising power threatens to displace a ruling power, shit happens." It's true of people, it's true of companies, and it's even more true of countries. It's also the fundamental insight captured by a
  75. with Ben Horowitz, Scott Kupor, and Caroline Moon“The only unforgivable sin in business is to run out of cash” [so said Harold Geneen], yet startup CEOs “always act on leading indicators of good news, and lagging indicators of bad news” [accor
  76. What is "infrastructure" actually? In the 19th and 20th century, that usually meant the transportation systems supporting roadways, airports, trains... but we don't even really know yet what it might potentially mean in the age of rapidly chang
  77. with Clayton Christensen, Marc Andreessen, and Steven LevyIn business, mistakes of omission may be just as bad as (if not worse than) mistakes of commission -- simply because of the loss in potential upside: new companies, new products, new op
  78. "Young hungry and scrappy" is how Hamilton described his country, and it's how many -- including the guests on this episode -- describe startups... or more precisely, the mindset that engineers in startups need to balance both creativity and ef
  79. We tend to talk about tech and parenting through devices and artifacts -- screen time, to code or not to code -- but actually, there's a bigger, macro picture at play there: game theory, economic incentives, culture, and more. So in this back-t
  80. with Russ Roberts, Noah Smith, and Sonal ChokshiBeyond the overly simplistic framing of trade as “good” or “bad” — by politicians, by Econ 101 — why is the topic of trade (or rather, economies and people adjusting to trade) so damn hard? A big
  81. with Michael Dearing (@mcgd), Bob Sutton (@work_matters), and Hanne Tidnam (@omnivorousread)Bob Sutton's book The No Asshole Rule was all about how to foster company cultures that don't tolerate asshole behavior. But sometimes, dealing with an
  82. with Juan Benet and Chris DixonThe story of how innovation happens is a long one — from government funding early basic research, to the heyday of corporate R&D like Bell Labs, to startups as experiments before product-market fit. Through all t
  83. with Wei Luo, David Rumsey (@davidrumseymaps), and Hanne Tidnam (@omnivorousread)In this episode, Wei Luo, founding COO of DeepMap -- who build HD maps for autonomous vehicles -- and David Rumsey, founder of the David Rumsey Map Collection (on
  84. with David Mack, Joseph Okpaku, and Matt SpenceHow should startups engage with policymakers, build their own government relations (GR) function (whether in house or with consultants), and just begin to figure out their GR playbook? Let alone e
  85. with Chris Dixon and Fred EhrsamWe’ve already talked about why bitcoin matters. But as the set of cryptocurrencies — and networks and “tokens” enabled by the underlying blockchain — grow (Ethereum being one of the fastest-growing ones), where
  86. Head of the largest bioengineering lab in the world, former chairman of the FDA and one of the few recipients of the National Medals of Science and of Technology and Innovation, Bob Langer's work has spanned multiple fields and settings and has
  87. with Ion Stoica, Peter Levine, and Sonal ChokshiWe’ve already talked quite a bit about the Algorithms, Machines, and People lab at U.C. Berkeley (AMPLab) — all about making sense of big data — so what happens when the entire world moves toward
  88. with Tim O'Reilly and Benedict EvansIn this hallway-style podcast conversation, O'Reilly Media founder Tim O'Reilly and a16z partner Benedict Evans discuss how we make sense of the most recent wave of new technologies --- technologies that are
  89. with Frank Chen, Steven Sinofsky, and Sonal ChokshiThere are many reasons why we’re in an “A.I. spring” after multiple “A.I. winters” — but how then do we tease apart what’s real vs. what’s hype when it comes to the (legitimate!) excitement ab
  90. with Martin Casado, Alex Rampell, and Sonal ChokshiOne of the trickiest things to pull off is B2B2C -- which combines both business to business (B2B) and business to consumer (B2C) -- yet this business model still seems like a tempting treat
  91. Author and professor at George Mason University, Peter Leeson describes himself as not just an economist but as a "collector of curiosa." In his latest book, WTF?! An Economic Tour of the Weird, Leeson looks at just that -- the strangest belief
  92. with Brandon Ballinger (@bballinger), Mintu Turakhia (@leftbundle), Vijay Pande (@vijaypande), and Hanne Tidnam (@omnivorousread)There’s been a lot of talk about technology -- and AI, deep learning, and machine learning specifically -- finall
  93. There's a new C-level role in town: the CCO, or Chief Customer Officer. This episode (based on a previous event) is all about the rise of this new role, why it's so important -- and what the actual scope and function of the role should be.a16z
  94. When you have “a really hot, frothy space” like AI, even the most basic questions — like what is it good for, how do you make sure your data is in shape, and so on — aren’t answered. This is just as true for the companies eager to adopt the tec
  95. Data, data, everywhere, nor any drop to drink. Or so would say Coleridge, if he were a big company CEO trying to use A.I. today -- because even when you have a ton of data, there's not always enough signal to get anything meaningful from AI.Wh
  96. NASDAQ CEO Adena Friedman runs one of the world's largest financial services companies, including the NASDAQ stock exchange that's home to more than 3,500 listed companies. They were also the creator of the world's first electronic stock market
  97. No matter how grand a vision for a particular industry, disruption in practice is hard. This is especially true in industries like healthcare, which have long been resistant to software-driven change. But sometimes you can innovate within the b
  98. No matter how grand a vision for a particular industry, disruption in practice is hard. This is especially true in industries like healthcare, which have long been resistant to software-driven change. But sometimes you can innovate within the b
  99. with Lee Kleinman (@LeeForDallas), Joshua Schank (@joshuaschank), Andrew Savage, and Hanne Tidnam (@omnivorousread)There's a new wave of bike-sharing in town. But this wave looks a little different than previous waves -- from docked rows of go
  100. As cars become more like iPhones and less like just, well, cars — everything changes, from data to mapping to interfaces to security and more. How so? Where are we anyway, given all the hype around when self-driving cars will appear everywhere?
  101. In this hallway conversation of the a16z Podcast, Benedict Evans and Steven Sinofsky discuss CES 2018 and share insight on what they took from this year's show. How much can you discern each company's "big picture" strategy out of the slew of n
  102. This episode of the a16z Podcast goes deep on various trends in cryptocurrencies -- from mental models for understanding tokens and what may give them long-term value; to the role of stablecoins in the ecosystem; to scaling, on-chain and off-ch
  103. It's surprising that how (and what) we eat has actually changed very little over the ages, despite how much we’ve advanced as a species. Now, however -- driven by globalization, environmental factors, and other considerations -- the way we move
  104. The complete sequencing of the human genome is one of the most powerful examples of technology and science in action: We've gone from needing $3 billion and over 13 years to read a single human genome to today, to where we can do that same amou
  105. New fintech companies are democratizing access to financial services in different ways, whether it's making food stamps more efficient, no longer waiting two weeks for a paycheck, or enabling anyone with a smartphone in developing countries to
  106. The internet, believe it or not, was just the beginning. Yes, it spawned an incredible number of uses (some unexpected), from marketplaces and commerce to publishing and social networks... but that’s all been built with old models of funding an
  107. What capabilities do enterprise companies really want from their computers? Twenty years ago, those capabilities might've been bundled into a mainframe. Ten years ago, it might've been the PC. Today, as more and more businesses rely on devices
  108. Many of the big tech policy issues of the day play out more so at the state and local level, not just federal level. The decisions that cities and states make every day -- from autonomous vehicles to bike sharing -- may therefore end up setting
  109. This conversation between the members of a16z's bio team -- including general partners Jorge Conde and Vijay Pande; Malinka Walaliyadde; and Jeffrey Low (the interviewer) -- takes a quick pulse on where we are with when bio becomes more like en
  110. We’re so used to thinking of “community” as our friends, families, and neighbors. But what a community is, and who it is made of, has changed thanks to the internet, and without our noticing it. What happens when online communities -- really, n
  111. There was a lot of hype about VR ad then it seemed to go pretty quiet. So where are we right now? Bigscreen founder Darshan Shankar and a16z general partner Chris Dixon take the pulse on VR, AR, and mixed reality -- especially where it's going
  112. The battle between every startup and incumbent comes down to whether the startup gets distribution before the incumbent gets innovation, oft observes a16z general partner Alex Rampell. But how does this play out when most of the players, big an
  113. In 2017 The Economist declared data to be the world's most valuable resource. And yet “data insight” is one of those phrases that, while important, is now so ubiquitous it’s been numbed of meaning. So how do you actually get the most meaningful
  114. As people begin to gain access to information that was previously left to only trained specialists, a new set of asset classes are being created -- and they are changing the way we think about everything from banking to customizing portfolios a
  115. Every large company -- especially ones that have been around for a long time -- goes through multiple cycles of change. But how do you know where to go next, and when, and how? The management literature is full of case studies, research, and of
  116. Once upon a time it was inconceivable that a company in Silicon Valley could make content that was any good; the running joke, shares Marc Andreessen, "was like, what are we gonna do -- we're gonna film a router instruction manual? It was just
  117. with Adam Bry (@adampbry), Chris Dixon (@cdixon), and Hanne Tidnam (@omnivorousread)Now that we've finally reached the age of the truly autonomous commercial small drone -- and in this case, a self-flying camera -- what happens when you take t
  118. with Martin Casado (@martin_casado), Michel Feaster (@michelfeaster) and Sonal Chokshi (@smc90)The purpose of category creation, argue the guests in this episode of the podcast, isn't just about making a dent in the way companies work and chan
  119. with Joel de la Garza, Stina Ehrensvärd, Niels Provos, and Martin CasadoGiven the heated discussions around security and the c-word (“cyber”), it’s hard to figure out what the actual state of the industry is. And clearly it’s not just an acade
  120. When most people think of space, they think of outer space: Mars, billionaires with rockets, and the “final frontier”. But space innovation is actually playing out right now -- in an immediate and more accessible way, thanks to techonologies ge
  121. What happens when monolithic architectures are broken down into containers and microservices (or when things are broken down into smaller units, not just in infrastructure but perhaps even in company structure too)? From building more dynamic w
  122. with Cristina Cordova (@cjc), Augusto Marietti (@sonicaghi), Laura Behrens Wu (@laurabehrenswu), and Sonal Chokshi (@smc90)APIs (application programming interfaces), observe the guests in this episode of the a16z Podcast, can be described as e
  123. Few operators become VCs, and even fewer go back to leading companies... so how does these perspectives change how one leads? Obviously, it's a lot easier to think of a solution than execute on one... but then how does a leader empower one's te
  124. with Lisa Hawke (@ldhawke) and Steven Sinofsky (@stevesi)Given concern around data breaches, the EU Parliament finally passed GDPR (General Data Protection Regulation) after four years of preparation and debate; it goes into enforcement on May
  125. The creation of each new biotechnology enables a tool, a therapy, or a diagnostic: a molecule, a protein, an app, a platform. And the process underneath isn't just complex in the science and engineering of it, but in the go to market.So who ar
  126. Many of the healthcare headlines lately have been about consolidation in the industry: Walmart and Humana; Aetna and CVS; Amazon, JP Morgan, and Berkshire Hathaway. But what does it all mean for patients, and startups -- Will it decrease costs?
  127. with Ray Dalio (@raydalio), Alex Rampell (@arampell), and Sonal Chokshi (@smc90)Can one really apply the lessons of history and of the past to the present and the future, as a way to get what they want out of life? By deeply understanding caus
  128. with Atul Butte (@atulbutte), Daphne Koller (@daphnekoller), and Vijay Pande (@vijaypande)Whether you’re an academic seeking to move out of research and into industry, or simply interested in working at a bio startup, this episode of the a16z
  129. with Bryan Caplan (@bryan_caplan), Marc Andreessen (@pmarca), and Sonal Chokshi (@smc90)Signaling and credential inflation -- not learning -- can explain why education pays in the labor market, and why we shouldn't invest (any more) in it, arg
  130. What challenges do first-time founders or tech founders encounter when building companies in the bio space, and how do they differ from traditional tech companies? In this hallway-style conversation (originally recorded as a video), a16z bio te
  131. What challenges do first-time founders or tech founders encounter when building companies in the bio space, and how do they differ from traditional tech companies? In this hallway-style conversation episode of the a16z Podcast (originally recor
  132. “The rules of the game are different in tech,” argues — and has long argued, despite his views not being accepted at first — W. Brian Arthur, technologist-turned-economist who first truly described the phenomenon of “positive feedbacks” in the
  133. When it comes to B2B2C business models -- which combine both business to business (B2B) and business to consumer (B2C) -- who really "owns" the customer? That question might not matter as much in more symbiotic, mutually beneficial marketplaces
  134. The International Consortium of Investigative Journalists is the organization responsible for the compilation and release of the first the Panama Papers, a series of 11.5 million documents that detailed the offshore dealings of governments and
  135. with Gregory Allen (@Gregory_C_Allen), Gayle Lemmon (@gaylelemmon), Ryan Tseng, and Hanne Tidnam (@omnivorousread)We now live in a world where connecting the dots between intel and modeling threats has become infinitely more complex: not only
  136. Here's the hard thing about security: the more authentication factors you have, the more secure things are... but in practice, people won't use too many factors, because they want ease of use. There's clearly a tension between security and usab
  137. There are over 20 million programmers out there -- and double that, if you count everyone else coding in other ways -- but where are the next 100 million developers? How do we get to a billion developers? The answer, observes a16z general partn
  138. with Greg Lynn (@greglynnform), Gina Neff (@ginasue), Tracy Young (@Tracy_Young), and Hanne Tidnam (@omnivorousread)Construction has been one of the industries most resistant to innovation and change over the last decades -- productivity has a
  139. with Martin Fischer (@fischermartin), Saurabh Ladha (@ladhasaurabh), Chris Rippingham, and Hanne Tidnam (@omnivorousread)Continuing our series on how tech is changing construction -- one of the industries most resistant to change (and facing d
  140. Compensation is a topic near and dear to everyone’s heart… but what does “compensation” fully mean — and what does it include, what doesn’t it include? How do entrepreneurs compete for talent in an intensely competitive environment, while balan
  141. with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Steven Johnson (@stevenbjohnson)The rise of zero-sum thinking -- which has come snapping back recently -- slows and even halts progress, observes Marc Andreessen. Because you're th
  142. with Ken Coleman, Ben Horowitz (@bhorowitz), and Michel Feaster (@michelfeaster)Everyone talks about the importance of mentorship in our professional development, whether it's networking to broaden career opportunities or learning from someone
  143. with Jorge Conde (@jorgecondebio), David Reich, and Hanne Tidnam (@omnivorousread)Trying to reconstruct the deep past of ancient humans out of present-day people has until now been like trying to reconstruct a bomb explosion in a room from bit
  144. with Chris Dixon (@cdixon), Elizabeth Stark (@starkness), and Jessica Verrilli (@jess)Why does decentralization matter? This episode of the a16z Podcast -- based on a discussion that first took as part of an “Intro to Crypto” event that Andree
  145. with Tina Bhatnagar (@tinab), Preethi Kasireddy (@iam_preethi), Lily Liu (@calilyliu), and Kim Milosevich (@kimbatronic)Whether it’s sharing the decision-making behind joining a crypto company to the perspectives of a passionate early adopter
  146. with Elad Gil (@eladgil) and Chris Dixon (@cdixon)There's a lot of knowledge out there -- and networks of talent (especially in Silicon Valley) -- on what to do in the early stages of a company, going from 0 to 1, and even in going from 1 to 1
  147. with Chris Dixon (@cdixon), Ali Yahya (@ali01), and Devon Zuegel (@devonzuegel)“Show me the incentive and I'll show you the outcomes.”At the end of the day, observes a16z crypto general partner Chris Dixon, Satoshi's whitepaper [the original
  148. with Denis Nazarov (@iiterature), Jesse Walden (@jessewldn), Ali Yahya (@ali01), and Devon Zuegel (@devonzuegel)Cryptonetworks are often compared to firms, people, or even coral reefs -- but, observes a16z crypto partner Ali Yahya, they might
  149. with Ben Horowitz (@bhorowitz) and Sharon Chang (@sychang)What does it really take to start a startup (or work at one)? In this episode of the a16z Podcast -- based on a Q&A with Ben Horowitz as part of an event hosted by a16z's Technical Tale
  150. with Andrew Chen (@andrewchen), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90)Growth is one of the most top of mind questions for entrepreneurs building startups of all kinds (and especially consumer ones) -- but how does one go beyond
  151. with Andrew Chen (@andrewchen), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90)Once you have users, how do you keep them engaged, retain them, and even "resurrect" or re-engage them? That's the focus of this episode of the a16z Podcast,
  152. with Devon Zuegel (@devonzuegel), Denis Nazarov (@iiterature), and Jesse Walden (@jessewldn)The open source movement enabled so much in computing, including the collaborative building of libraries -- that is, building blocks of code that devel
  153. with Martin Casado (@martin_casado), Andrew Chen (@andrewchen), Russ Heddleston (@rheddleston), and Hanne Tidnam (@omnivorousread)What happens when the bottoms up, organic growth usually associated with consumer companies starts to go.... ente
  154. with Jeff Jordan (@Jeff_Jordan), Cal Turner Jr., and Hanne Tidnam (@omnivorousread)The "death of retail" in the face of e-commerce and tech disruption is a very real phenomenon, but what about the flip side of that story -- that is, retail thr
  155. with Steven Johnson (@stevenbjohnson), Chris Dixon (@cdixon), and Sonal Chokshi (@smc90)There's a lot of research and writing out there on "thinking fast" -- the short-term, gut, instinctual decisions we make, biases we have, and heuristics we
  156. with Benedict Evans (@BenedictEvans) and Steven Sinofksy (@StevenSi)In this hallway-style conversation episode of the a16z Podcast, Benedict Evans and a16z board partner Steven Sinofsky discuss Apple’s September 2018 keynote event and share th
  157. with Benedict Evans (@BenedictEvans) and Steven Sinofsky (@SteveSi)In another of our hallway conversation episodes, Benedict Evans and Steven Sinofsky talk all about Tesla — and more broadly, the nature of disruption overall. How disruptive is
  158. with Fred Wilson (@fredwilson) and Chris Dixon (@cdixon)There's all sorts of interesting tech trends happening right now, including AI, VR/AR, self-driving cars and drones (as well as interesting stuff happening in verticals like healthcare an
  159. with Michael Ovitz (@michaelovitz), Ben Horowitz (@bhorowitz), and Hanne Tidnam (@omnivorousread)When Michael Ovitz co-founded the Hollywood talent agency Creative Artists Agency (CAA), he turned a number of the entertainment industry's well-e
  160. with Shannon (Stubo) Brayton (@sstubo), Margit Wennmachers (@wennmachers), and Sonal Chokshi (@smc90)One of the company building topics that’s surprisingly mystifying is PR -- and only surprising since so much of the strategy and tactics behin
  161. The period from 2000-2016 was one of the best of times and worst of times for tech and the Valley (dotcom, financial crisis, Google IPO, Facebook founded, unprecedented growth, and so on), and John Hennessy -- current chairman of Alphabet, also
  162. with Jeff Jordan (@Jeff_Jordan), Yogi Roth (@YogiRoth), Zack Weiner and Hanne Tidnam (@omnivorousread)For decades, the increasing value of sports teams, rights, licenses and more have been fueled by sports media. But dollars follow eyeballs, a
  163. with Prasad Akella, Paul Daughtery (@pauldaugh) and Frank Chen (@withfries2)What is different on that factory floor from Henry Ford to today? In this conversation, Prasad Akella, Founder and CEO of Drishti; Paul Daugherty, Chief Technology and
  164. with Stephanie Cohen and Martin Casado (@martin_casado)As chief strategy officer of Goldman Sachs (and former global head of financial sponsors M&A), Stephanie Cohen has seen it all when it comes to the ins and outs of M&A. And what it means t
  165. with Adrienne Mayor (@amayor) and Hanne Tidnam (@omnivorousread)Is it possible that ancient Greeks and Romans dreamed of technological innovations like robots and artificial intelligence millennia before those technologies became realities? In
  166. with Boris Sofman (@bsofman), Dave Touretzky (@DaveTouretzky), and Hanne Tidnam (@omnivorousread)We're just now beginning to truly see the the first 'real' robots in the home, from Roombas to toys to companions to... well, much more. How are h
  167. with Jeffrey Katzenberg, Meg Whitman (@MegWhitman), and Marc Andreessen (@pmarca)In this episode of the a16z Podcast, based on a discussion that took place at our annual a16z Summit, Marc Andreessen interviews Jeffrey Katzenberg -- formerly CE
  168. with Brian Armstrong (@brian_armstrong), Chris Dixon (@cdixon), and Sonal Chokshi (@smc90)Where are we, really, right now -- in terms of what we can/ can't do with crypto today? And what will it take to get from vision to mainstream reality? T
  169. with Bernard J. Tyson (@bernardjtyson) and Ben Horowitz (@bhorowitz)Bernard J. Tyson is the chairman and CEO of Kaiser Permanente, a $73 billion non-profit health organization that provides healthcare and coverage with more than 22,000 physici
  170. with Andy Milenius (@realzandy), Jesse Walden (@jessewldn), and Sonal Chokshi (@smc90)The history, evolution, and use of money revolves around the important concept of debt: It’s what allows us to “time travel” and build toward the future — gr
  171. In his book (and podcast), Brian McCullough chronicles the history and evolution of the internet -- from college kids in a basement and the dot-com boom, to the applications built on top of it and the entrepreneurs behind them.General partner
  172. with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen)This episode of the a16z Podcast features the rare combination of a16z co-founders Marc Andreessen and Ben Horowitz in conversation, together, with economi
  173. The past and future of marketplace startups -- where are we? Ever since eBay popularized an internet meeting place for buyers and sellers of, well, just about everything, we’ve been waiting for 100 other at-scale marketplaces for everything els
  174. with James J. Collins, Vijay Pande (@vijaypande), and Hanne Tidnam (@omnivorousread)The idea of 'designing biology' -- once science fiction -- has over the last 20 years become just... science. In this episode, a16z bio general partner Vijay P
  175. with Vas Narasimhan (@vasnarasimhan), Jorge Conde (@jorgecondebio), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90)On average, only 1 out of 20 medicines works when we actually bring them into the human body, and these rates of success ha
  176. with Susannah Fox (@susannahfox), Anil Sethi (@anilsethiusa / @ciitizencorp), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90)The problem of "dark data" in healthcare isn't just a feel-good empowerment thing, but a structural issue that l
  177. with Benedict Evans (@benedictevans) and Steven Sinofsky (@stevesi)Every year, the Consumer Electronics Show (CES) puts the latest and greatest developments in consumer technology on display in Vegas. But beyond the excitement and the hype, wh
  178. with Joel de la Garza, Jonathan Lusthaus, and Hanne Tidnam (@omnivorousread)The idea of the cybercriminal as lone wolf or hobby hacker is no longer much of a reality. Instead, the business of cybercrime looks a lot more just like that -- a lar
  179. Veterinary oncology can inform human oncology, and vice versa -- providing a better model for looking at drug performance, interrelationships, and more. Especially when you add in data (there's no "doggy HIPAA!") and networks to get a "living l
  180. with Peter Levine, Bob Tinker, and Hanne Tidnam (@omnivorousread)For consumer companies, often when the holy grail of product-market fit is achieved, the company takes off: magic happens, growth unlocks. Enterprise B2B companies face a differe
  181. with Mark Leslie (@mleslie45) and Peter LevineWhat does it actually take to win at enterprise sales? In this episode, Mark Leslie, former CEO and chairman and founding team member of Veritas Software, and a lecturer at the Stanford Graduate Sc
  182. with Jyoti Bansal (@jyotibansalsf), Peter Levine, Satish Talluri (@satishtalluri), and Sonal Chokshi (@smc90)One of the toughest challenges for founders -- and especially technical founders who are used to focusing so much on product features 
  183. with Phil Daian (@phildaian) and Ali Yahya (@ali01)Whether in corporations, boardrooms, or political elections, voting is something we see in all kinds of social systems... including blockchains. It's the natural human tendency for how to orga
  184. with Chris Burniske (@cburniske), Joel Monegro (@jmonegro), Denis Nazarov (@Iiterature), and Jesse Walden (@jessewldn)When designing cryptonetworks -- really, emerging economies -- how do we avoid some of the monetary and fiscal policy failing
  185. with Kate Darling (@grok_) and Hanne Tidnam (@omnivorousread)We already know that we have an innate tendency to anthropomorphize robots. But beyond just projecting human qualities onto them, as we begin to share more and more spaces, social an
  186. with Ryan Caldbeck (@ryan_caldbeck), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90)It's clear that all kinds of commerce companies and consumer products have been disrupted -- or enabled -- by tech. Yet for certain categories, like con
  187. Bobby Kotick is the CEO of Activision Blizzard (a merger he engineered); it's one of only two video gaming companies in the Fortune 500, and the largest game network in the world. The company is responsible for some of the most iconic entertain
  188. with Peter Ludwig, Qasar Younis (@qasar), and Sonal Chokshi (@smc90)When people talk about autonomous vehicles, we hear everything from "we're much closer than you think" to "we're much further than you think". So where are we, really, in the
  189. with George Church (@geochurch) and Jorge Conde (@JorgeCondeBio)Renowned scientist George Church is known for his groundbreaking work and methods used for the first genome sequence, and for his work in genome editing, writing & recoding -- in
  190. When people talk about trends in education technology, they often focus on how to disrupt higher education in the U.S., whether it's about breaking free of the "signaling" factor of elite educations or how to shift education out of its "cottage
  191. with Brian Koppelman (@briankoppelman), Marc Andreessen (@pmarca), and Sonal Chokshi (@smc90)The writer-showrunner is a relatively new phenomenon in TV, as opposed to film, which is still a director-driven enterprise. But what does it mean, as
  192. with Safi Bahcall (@safibahcall), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90)A "moonshot" is a destination (like going to the moon, quite literally) -- but nurturing "loonshots" (which often involves a number of stumbles along the way
  193. with Benedict Evans (@benedictevans) and Steven Sinofsky (@stevesi)What does Apple's recent event — in which a range of new services was announced, from Apple News Plus to Apple TV Plus to the Apple card — mean for the company's overall strateg
  194. with Nick Quah (@nwquah), Connie Chan (@conniechan), and Sonal Chokshi (@smc90)It's a podcast about podcasting! About the state of the industry, that is. Because a lot has changed since we recorded "a podcast about podcasts" about four years ag
  195. In this episode of the a16z Podcast -- which originally aired as a video on YouTube -- general partner Alex Rampell (and former fintech entrepreneur as the CEO and co-founder of TrialPay) talks with operating partner Frank Chen about the quickl
  196. Join longtime Apple software engineer Ken Kocienda in conversation with a16z Deal and Research operating partner Frank Chen for an insider’s account of how Apple designed software in the golden age of Steve Jobs, spanning products like the firs
  197. with Jorge Conde (@JorgeCondeBio), Julie Yoo (@julesyoo), and Hanne Tidnam (@omnivorousread)Building a software company in healthcare is hard -- and comes along with unique challenges no other entrepreneurs face. In this conversation, a16z bio
  198. As companies digitize, they change the way they make decisions: decisions are made lower in the organization, based on data, and increasingly automated. This creates opportunities for startups creating new ways to collect and analyze data to su
  199. In a followup to one of our most popular podcast episodes which originally aired in April 2017 (https://a16z.com/2017/04/03/cryptocurrencies-protocols-appcoins/), a16z Crypto Fund General Partner Chris Dixon returns to talk with Olaf Carlson-We
  200. with @annieduke, @pmarca, and @smc90Every organization, whether small or big, early or late stage -- and every individual, whether for themselves or others -- makes countless decisions every day, under conditions of uncertainty. The question is
  201. with Emily Oster (@ProfEmilyOster) and Hanne Tidnam (@omnivorousread)Are chia seeds actually that good for you? Will Vitamin E keep you healthy? Will breastfeeding babies make them smarter? There’s maybe no other arena where understanding what
  202. Do you sometimes wish you had been born in a different decade so you could have worked on the fundamental building blocks of modern computing? How fun, challenging, and fulfilling would it have been to work on semiconductors in the 1950s or Uni
  203. with David Ulevitch (@davidu) and Sonal Chokshi (@smc90)Since the startup (and founder) journey doesn't go neatly linear from technical to product to sales, tightening one knob (whether engineering or marketing or pricing & packaging) creates s
  204. with Laurene Powell Jobs (@LaurenePowell) and Ben Horowitz (@bhorowitz)Laurene Powell Jobs is, among many other things, founder and President of the Emerson Collective -- the social impact firm she founded to drive change and reform through phi
  205. with Andrew Lo (@AndrewWLo) and Jorge Conde (@JorgeCondeBio)The advent of new gene and cell therapies are beginning to approach that holy grail of medicine—that of a possible cure. But they are also more expensive than any medicines ever sold b
  206. with Van Jones (@VanJones68), Shaka Senghor (@ShakaSeghnor), and Chris Lyons (@clyons)True redemption can be hard to come by in our justice system today. And yet, we need it more than ever before. In this episode (based on an event hosted by An
  207. with Vijay Pande (@vijaypande) and Bharath RamsundarDeep learning has arrived in the life sciences: every week, it seems, a new published study comes out... with code on top. In this episode, a16z General Partner Vijay Pande and Bharath Ramsund
  208. Want actionable advice from a founder who has built multiple tech companies and has invested the time to be open, introspective, and transparent about lessons learned?In this episode (which originally aired as a YouTube video), a16z General Par
  209. with Eric Topol (@EricTopol) and Vijay Pande (@vijaypande)Artificial intelligence is coming to the doctor’s office. In this episode, Dr. Eric Topol, cardiologist and chair of innovative medicine at Scripps Research, and a16z’s general partner o
  210. with Tony Blair (@InstituteGC), Scott Kupor (@skupor), and Sonal Chokshi (@smc90)If the current pace of tech change is the 21st-century equivalent of the 19th-century Industrial Revolution — with its tremendous economic growth and lifestyle cha
  211. How have we gotten to where were are with machine learning? Where are we going?a16z Operating Partner Frank Chen and Carnegie Mellon professor Tom Mitchell first stroll down memory lane, visiting the major landmarks: the symbolic approach of th
  212. Synthetic fraud—yes, it's a thing: a new evolution of consumer fraud that’s been emerging in financial services, to the tune of $1-$2B a year.In this episode of the a16z Podcast, Naftali Harris, co-founder and CEO of Sentilink, which builds tec
  213. Two recent scientific journal papers show what's possible when CRISPR moves from cutting DNA tool to a full-fledged platform -- expanding its toolkit for medicine across R&D, therapeutics, and diagnostics:"Transposon-encoded CRISPR-Cas systems
  214. with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Stewart Butterfield (@stewart)A lot in technology -- and venture -- happens in decades. New cycles of technology come and go, including some secular shifts; a new generation of fou
  215. with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Michael CopelandContinuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring Andreesse
  216. with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), Scott Kupor (@skupor), and Sonal Chokshi (@smc90)Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous
  217. with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Steven Johnson (@stevenbjohnson)Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes fea
  218. with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen)Continuing our 10-year anniversary series since the founding of Andreessen Horowitz (aka "a16z"), we’re resurfacing some of our previous episodes featuring
  219. Incentives matter. So understanding the incentives of venture capitalists will help you decide if raising money from a venture investor makes sense for your business.In this first of a 3-part series, which originally aired as YouTube videos, a1
  220. So you've decided raising venture capital is the best fundraising strategy for your startup. Now what?In this second of a 3-part series, a16z Managing Partner Scott Kupor shares actionable fundraising advice based on his experience of seeing th
  221. In this final of a 3-part series (which originally aired as YouTube videos) on working with venture investors, a16z Managing Partner Scott Kupor shares best practices for working with your board as it grows from just you, your co-founders and f
  222. with @vijaypande @conniechan @jpm25 and @smc90Introducing our new podcast, 16 Minutes, a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from ou
  223. with Kurt House (@kurtzhouse), John Thompson, Connie Chan (@conniechan) and Hanne Tidnam (@omnivorousread)The exploration for and mining of certain metals has driven huge epochs of human civilization, from copper and iron to gold and diamonds.
  224. with @martin_casado @jorgeconde @jayrughani and @smc90This is episode #2 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -
  225. with @andrewchen @dcoolican and @smc90This is episode #3 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our
  226. with @jorgecondebio @vijaypande and @smc90This is episode #4 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share
  227. with @astrange @jeff_jordan and @smc90This is episode #5 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our
  228. with @julesyoo @smc90This is episode #6 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts' views o
  229. Back in 2011, a16z cofounder Marc Andreessen first made the bold claim that software would eat the world. In this episode (originally recorded as part of an event at a16z), Andreesseen and a16z general partner on the bio fund Jorge Conde (@Jorg
  230. with @illscience and @smc90This is episode #7 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and share our experts'
  231. with @ldhawke and @stevesiThe government wants to get onto the cloud! But how do they assess the levels of risk in adopting specific cloud products, and which "cloud service providers" (aka "CSPs") to work with? That's where FedRAMP -- the Fed
  232. What can we learn from the history of the internet for the future of crypto? In this episode of the a16z Podcast, general partner Katie Haun interviews a16z co-founder Marc Andreessen -- and co-founder of Netscape, which helped popularize and m
  233. "You cannot be IN it... and not be OF it."Dapper Dan a.k.a. Daniel Day shares his remarkable history and story of defining an era of fashion and cultural influence in this special episode of the a16z Podcast — based on his conversation in San
  234. We're excited to introduce a new podcast series hosted by a16z co-founder Ben Horowitz and Shaka Senghor, a leading voice in criminal justice reform and bestselling author. The series is called “Hustlin’ Tech” and so far, there are three episod
  235. with @bhorowitz @shakasenghor @8ennett & sherie jamesHustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology platforms -- and mindsets -- for everybody and anybody who has the desire, the talent, and the hustle to
  236. with @bhorowitz @shakasenghor ram @earnin & vaughn fergusonHustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology platforms — and mindsets — for everybody and anybody who has the desire, the talent, and the hustl
  237. with @bhorowitz @shakasenghor @diishanimira @therealritabeeHustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology platforms -- and mindsets -- for everybody and anybody who has the desire, the talent, and the hus
  238. There's been a lot of talk about the need for our healthcare system to shift away from volume and fee-for-service, where you pay by appointment, procedure, etc, to value-based care, where you pay for both quality and outcomes—essentially, good
  239. with @benedictevans @vijaypande and @smc90This is episode #8 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're in the news; why they matter from our vantage point in tech -- and shar
  240. What is the nature of physical pain? Why do we even experience it? Is there one type, or many? Do people experience pain differently? What is happening in our brains and our bodies when we experience pain? What is the biological link between pa
  241. This is episode #9 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they’re in the news; why they matter from our vantage point in tech -- and share our experts’ views on the trends involved
  242. The combination of cloud, social, and mobile took gaming beyond a small base of just console- and PC-gamers to a massive player base. But the underlying business model -- the concept of "free-to-play", built on top of games-as-a-service -- may
  243. Our news podcast, 16 Minutes -- where we quickly cover the top headlines of the week, the a16z way (why are these topics in the news; what's real, what's hype from our vantage point of tech trends) -- is now only available as its own show feed,
  244. It used to be that the only way for humanity to grow -- and progress -- was through destroying the environment. Sure, the Industrial Revolution brought about the growth of our economies, our population, our prosperity; but it also led to our ex
  245. This rerun podcast (first recorded in 2015, now being rerun as one of our evergreen classics/ favorites) -- is ALL about emoji. But it's really about how innovation really comes about: through the tension between open standards vs. closed/ prop
  246. Today, despite the critical importance of open source to software, it’s still seen by some as blasphemous to make money as an open source business. In this podcast, Armon Dadgar, Cofounder and CTO of HashiCorp; Ali Ghodsi, CEO of Databricks; an
  247. Consumer software may have adopted and incorporated AI ahead of enterprise software, where the data is more proprietary, and the market is a few thousand companies not hundreds of millions of smartphone users. But recently AI has found its way
  248. The games industry is in the midst of a tectonic shift. Powered by platform convergence, games-as-a-service, and user-generated content, modern video games—what we call next-generation games—are unlike anything we've seen before. In the past de
  249. Many technical founders, academics, and other experts often believe that great products -- or great ideas! -- sell themselves, without any extra effort or marketing. But in reality, they often need PR (public relations).The irony is, most of th
  250. "Hi everyone, welcome to the a16z Podcast..." ... and welcome to our 500th episode, where, for the first time, we reveal behind-the-scenes details and the backstory of how we built this show, and the broader editorial operation. [You can also l
  251. "Constant attention by a good nurse may be just as important as a major operation by a surgeon”, diplomat Dag Hammarskjöld once observed -- and that may be more true today than ever before. For most of us, nurses are essentially the face of the
  252. This podcast rerun -- first recorded over two and a half years ago, now being rerun as one of our evergreen classics on the tails of the world's largest designated shopping days (Black Friday, Singles Day in China, Prime Day online, and so on)
  253. There are some common tropes that can kill your company culture -- whether it's that corporate values can be weaponized; "fake it til you make it"; the "reality distortion fields" of visionaries vs. liars; and so on. All of this just reveals th
  254. We’ve covered a lot of the strategic financing milestones for startups seeking to build a sustainable and enduring business -- from mindsets for startup fundraising to when and how to build a finance functionwith a CFO to what it takes to do an
  255. As part of a new series where we will share select a16z partner appearances on other podcasts with our audience here, this episode is cross-posted from the new show Starting Greatness -- featuring interviews with startup builders before they we
  256. Hollywood and Silicon Valley seem so different, but are more alike than we think. What challenges do tech startup founders and other creative founders -- like showrunners and executive producers -- similarly face? Both have to deeply understand
  257. A bold proposal: You go to college for free, then pay back the school after graduation—but only if you get a job in your field of study and make a high enough salary to afford it. It's called an income share agreement, and Austen Allred, the CE
  258. When innovation and capital go global, so do restrictions on trade, foreign investment, and more. Over the past couple years, U.S. policymakers have expanded the scope of the Committee on Foreign Investment in the U.S. (CFIUS) through the Forei
  259. Many skeptics thought the internet would never reach mass adoption, but today it’s shaping global culture, is integral to our lives -- and it's just the beginning. In this conversation from our 2019 innovation summit, Kevin Kelly (Founding Exec
  260. This is a turn of the decade (and January-themed) look backward/ look forward into personal genomics, given recent and past retrospective and prospective pieces in the media on the promise, and perils, of the ability to sequence one's DNA: What
  261. How does the world’s largest producer of medicines in terms of volume balance the science and the business of innovation? How does an enterprise at such vast scale make decisions about what to build vs. buy, especially given the fast pace of sc
  262. The federal agency known as the FDA, or the Food and Drug Administration, was born over 100 years ago—at the turn of the industrial revolution, in a time of enormous upheaval and change, and rapidly emerging technology. The same could be said t
  263. AI can do a lot of specific tasks as well as, or even better than, humans can — for example, it can more accurately classify images, more efficiently process mail, and more logically manipulate a Go board. While we have made a lot of advances i
  264. How can we evolve the web for a better future? Has the web become a mature platform — or are we still in the early days of knowing what it can do and what role it might have in our lives? Just as “social/local/mobile” once did, what are the new
  265. We've been financing good writing with bad advertising -- and "attention monsters" (to quote Craig Mod) for way too long. So what happens when the technology for creators finally falls into place? We're finally starting to see shift in power aw
  266. The idea of "1000 true fans" -- first proposed by Kevin Kelly in 2008 and later updated for Tools of Titans -- argued that to be a successful creator, you don’t need millions of customers or clients, but need only thousands of true fans. Such a
  267. This episode of 16 Minutes on the news from a16z is all about the recent coronavirus outbreak -- or rather, a new type of coronavirus called 2019-nCoV for 2019 novel coronavirus. Since it's an ongoing and fast-developing news cycle, we take a q
  268. When we think about rebellious behavior in the context of organizations and companies, we tend to think of rebels as trouble-makers, rabble-rousers; in other words, people who make decisions and processes more difficult because they may not fol
  269. with @OzAzamTmunity1, @JorgeCondeBio, and @omnivorousreadCAR T therapy, the groundbreaking new medicines that uses engineered T-cells to attack cancer, has been so effective in childhood leukemias that we believe it may actually be a potential
  270. Susan shares how she learned to leverage the characteristics of her personality early in her career as assistant secretary of state [2:05]One of the important conversations Susan had with a mentor that changed the trajectory of her career [4:50
  271. It's "Marketplaces Week" for us at a16z, thanks to our consumer team releasing a new index of the next industry-defining marketplaces, the Marketplace 100.  But what happens as such marketplaces and other platforms evolve over time, as do their
  272. This episode covers the following -- since our previous deep-dive on the novel coronavirus outbreak -- including:practical implications for the U.S. healthcare system given how it works today, and where we might go in the future — with a16z gen
  273. In 2014, in "Why There Will Never Be Another Red Hat," Peter Levine argued that Red Hat’s open source business model of commercializing support and services was highly difficult to replicate. Instead, he predicted the future of open source comp
  274. One of the recurring themes we talk about a lot on the a16z Podcast is how software changes organizations, and vice versa... More broadly: it’s really about how companies of all kinds innovate with the org structures and tools that they have. B
  275. The last financial crisis prompted many consumers to reassess their banking expectations—none more so than millennials and Gen-Z-ers. While revealing one's financial information was once considered taboo, now consumers are more apt than ever to
  276. On February 21, Andreessen Horowitz kicked off its very first Crypto Startup School, with 45 students from around the U.S. and three countries gathering to learn how to build crypto projects. But just two weeks into the seven-week course, commu
  277. A lot's going on in the world of healthcare right now, and one topic that's especially relevant is how diagnostic labs work. In this episode with Dave King, Executive Chairman of Lab Corp (one of the largest clinical lab networks in the world)
  278. We’re at a moment where we are now seeing medicine go virtual faster, and at a scale that it has never done before. In this conversation,  a16z bio general partners Vijay Pande and Julie Yoo, who come from the worlds of bio, technology and care
  279. The spike in online ordering and food delivery—a trend that's particularly relevant now—is evidence of how tech is fundamentally changing how and what we eat. Is this the end of the traditional restaurant experience as we know it?In this conver
  280. We are in the midst of a rapid and unprecedented shift to remote work. What does it mean for security when the airgap between work and life is gone? How prepared are organizations? And what should security professionals as well as individual wo
  281. This is the next cycle of Hustlin' Tech -- a podcast series co-hosted by bestselling authors, a16z co-founder Ben Horowitz; and Shaka Senghor, a leading voice in criminal justice reform.   Each episode is a "Hustler's Guide" to a new technology
  282. This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for people. Recorded right before the coronavirus pandemic, these next 3 episodes touch on many thi
  283. This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for people. Recorded right before the coronavirus pandemic, these next 3 episodes touch on many thi
  284. This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for people. Recorded right before the coronavirus pandemic, these next 3 episodes touch on many thi
  285. Since social distancing measures were first put in place, time spent gaming has gone up—way up. According to a recent report by Verizon, video game usage in the U.S. has risen 75 percent during peak hours. The "stay at home" movement has given
  286. For any business, there are three core financial statements – the income or P&L statement, the balance sheet, and the cash flow statement. While these statements can show investors and the board how the business is doing, they can do more than
  287. Descriptions of the mental illness we today call schizophrenia are as old as humankind itself. And more than likely, we are are all familiar with this disease in some way, as it touches 1% of us—millions of lives—and of course, their families.
  288. with @vintweeta @pbcancerdoc @sumitshahmd @omnivorousreadCoronavirus is now disrupting the entire health care system, not just because of the burden of dealing with the actual disease itself, but because of everything else that's had to grind t
  289. From agile project management to asynchronous collaboration, development teams have pioneered many of the tools and best practices for remote work. However, new shelter-in-place orders have more organizations moving to remote development -- and
  290. with @JorgeCondeBio, @julesyoo, and @omnivorousreadIn some ways, the coronavirus feels like it came out of nowhere—a kind of Black Swan event. But at the same time, it's been exposing a lot of the fundamental flaws in our healthcare system that
  291. This episode of the a16z Podcast covers the the rise of online platforms that enable people to make a living off their unique interests and skills. It's a trend that's become increasingly relevant as the demand for virtual work grows. The discu
  292. We wanted to let you know about a special new series of posts occasionally read out loud from us  (you can learn more about the why and why now in episode #500 on how we podcast); we may release these in a separate feed in future, for now, the
  293. “It's Time to Build” by Marc Andreessen. You can also find and share this essay at a16z.com/build
  294. Here is Ali's tweetstorm on the Narrow Waist of Blockchain Computing 
  295. Announcing a16z Journal Club, a new show where we curate and discuss recent research papers with a16z experts and others. This new show continues the a16z Podcast mission of not just bringing you conversations about the future (as well as about
  296. The Chief Security Officer (CSO/CISO) used to manage on-premise servers, now the information they have to secure has migrated to the cloud. As the responsibility of CSOs has expanded, the role has moved from technical IT to the boardroom. How d

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