Michael N. Desvigne, MD, FACS, CWS, FACCWS and Dot Weir, RN, CWON, CWS discuss how to examine the clinical impact of Collagen with Oxidized Regenerated Cellulose (ORC) and Silver in the wound environment. They will explain the clinical significance of negative pressure wound therapy and determine when to use Collagen with Oxidized Regenerated Cellulose (ORC) and Silver Dressings and NPWT and who to use it on. They will also examine, via cases, the clinical outcomes from combining Collagen with Oxidized Regenerated Cellulose (ORC) and Silver with NPWT.