Harold Frederick Shipman (14 January 1946 – 13 January 2004), known to acquaintances as Fred Shipman, was an English general practitioner who is believed to be one of the most prolific serial killers in modern history. On 31 January 2000, he was found guilty of the murder of 15 patients under his care; his total number of victims was approximately 250. Shipman was sentenced to life imprisonment with the recommendation that he never be released.[4] He died by suicide, hanging himself in his cell at HM Prison Wakefield, West Yorkshire on 13 January 2004, a day before his 58th birthday.

Sylvia Marie Likens (January 3, 1949 – October 26, 1965) was an American teenager who was tortured and murdered by her caregiver, Gertrude Baniszewski, many of Baniszewski's children, and several of their neighborhood friends. This abuse incrementally lasted for three months before Likens died from her extensive injuries and malnourishment on October 26 in Indianapolis, Indiana.

Likens was increasingly neglected, belittled, sexually humiliated, beaten, starved, lacerated, and dehydrated by her tormentors. Her autopsy showed 150 wounds across her body, including several burns and receded skin. Through intimidation, her younger sister, Jenny, was occasionally forced to participate in her mistreatment. The official cause of her death was determined to be a homicide caused by a combination of subdural hematoma and shock, complicated by severe malnutrition.