The Doctor, Elan, and Jenni arrive in New Orleans, Louisiana in 1879, a town known for food, music, night life, and…for its ghosts. Rumors of Ghosts and Vampires haunt the infamous LaLaurie Mansion. With the help of the granddaughter of the Voodoo priestest Marie Laveau, the Doctor, Elan, and Jenni set out to prove once and for all there are no such things as Ghosts. But what could be causing the mysterious disappearances around the mansion?