After making her stand-up debut in Washington, D.C., Aparna Nancherla quickly became a comedy darling in Los Angeles and New York, writing for FX’s Totally Biased with Kamau Bell and Late Night with Seth Meyers. She also became a welcome fixture in New York’s competitive stand-up scene thanks to her smart and self-aware one-liners. When she opened up about her own anxiety and depression, more fans flocked. As a writer and actor, she has worked on HBO’s Crashing, Comedy’s Central’s Corporate, and Netflix’s Bo-Jack Horseman. Now she’s eager to explore new terrain in her next stand-up special but worries what fans and Hollywood will think. In her conversation with Catie Lazarus, Nancherla talks about the solitary nature of stand up and writing, the toll it takes to regularly joke about anxiety, and how to say no to too much work.