Episode 2227 - On this Saturday's show, we replay the first time Vinnie Tortorich speaks to Dr. Jason Fung and they discuss his book , insulin and weight loss, metabolic syndrome, intermittent fasting, and more. https://vinnietortorich.com/best-of-insulin-weight-loss-dr-jason-fung-episode-2227 PLEASE SUPPORT OUR SPONSORS INSULIN & WEIGHT LOSS Vinnie welcome Dr. Jason Fung, who is a kidney specialist. (2:05) He works often with type 2 diabetics -- the biggest cause of kidney nephropathy. Type 2 is linked closely with obesity. Insulin has negative effects.   Vinnie tells Dr. Fung about his visit to his hometown of Donaldsonville. (7:05) Everyone he met was on multiple medications. They all had some kind of sugary drink in their hands. They discuss how obesity is misunderstood; it is linked with several diseases and is often a part of metabolic syndrome. (8:00) Dr. Fung recommends . (9:00) Sugar is the enemy, not calories! Calories In, Calories Out (CICO) doesn't work or even make sense. (9:10) When you eat fewer calories, your energy expenditure (and thus fat/fuel usage) goes down. You simply get hungrier. It takes time to lose weight. Lots of things raise insulin, not just sugars and grains. (19:40) Insulin resistance leads to higher insulin levels. INTERMITTENT FASTING A key way to break insulin resistance is intermittent fasting. (23:20) Intermittent fasting should happen every day--Dr. Fung explains. (27:50) Having snacks doesn't allow your body to process all the hormones properly. (29:00) Shorter fasts aren't really enough. Dr. Fung explains the various fasting methods he recommends, even longer ones under medical supervision. Body switches to fat burning. (33:15) Obesity is a hormonal imbalance, not a caloric one. (42:00) Cortisol is a stress hormone -- encourages getting fat. Prednisone is a synthetic form of cortisol. Leptin is produced by fat cells and regulates how much fat is in the body If you have lots of fat, leptin is released and tells your brain to stop gaining more weight. When you are quite fat, your body stops responding to leptin. Leptin is a secondary hormone, so it doesn't pass the causal test. Ghrelin is another one of these secondary hormones; as a result, no lasting effect so doesn't pass the causal test either. Vinnie and Dr. Fung discuss a bit more about why CICO doesn't work. (45:00) Type 2 diabetes can be reversed in most cases; however, you can't treat a disease of having too much insulin by giving more insulin! (51:45) They give great comparisons as examples. There needs to be a grassroots movement for changes in the system; there are too many conflicts of interest with people who want to keep the meds going and how they fund things like universities. (53:40) NOTE: At the end of the show, Vinnie references Anna Vocino's old website, but she can now be found at . [the_ad id="20253"] PURCHASE BEYOND IMPOSSIBLE The documentary launched on January 11! Order it TODAY! This is Vinnie’s third documentary in just over three years. Get it now on Apple TV (iTunes) and/or Amazon Video! Link to the film on Apple TV (iTunes):  Then, Share this link with friends, too! It's also now available on Amazon (the USA only for now)!    Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. The more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. The more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter!