Summary:1. Staging - know where to look (based on primary site but also pathology)2. Restaging - know what to expect (based on type of treatment - XRT, chemo, immunotherapy)3. Big picture - same, better, worse; critical lesions that may require treatment (impending fractures, spinal cord involvement)4. Chose words carefully - careful about using “progression” unless you are going to calculate that this meets RECIST criteria - consider using “increased tumor burden” instead

Host: Christopher Cerniglia, DO, ME, FAOCR. Associate Professor of Radiology, Division of Musculoskeletal Imaging & Intervention, UMMS Dept of Radiology.Guest: Lacey J McIntosh DO, MPH. Assistant Professor of Radiology, Divisions of Abdominal Imaging and Nuclear Medicine, UMMS Dept of Radiology.

Resources:Wang, G. X., Kurra, V., Gainor, J. F., Sullivan, R. J., Flaherty, K. T., Lee, S. I., & Fintelmann, F. J. (2017). Immune checkpoint inhibitor cancer therapy: spectrum of imaging findings. Radiographics, 37(7), 2132-2144.