In recognition of 2012 World Overdose Day bit.ly/QnHQoR, a conversation with its originator Sally Finn; Eliza Wheeler of the Dope Project bit.ly/QKwrKq and Haven Wheelock of Portland’s Outside In bit.ly/fsVzTG talk about preparations for the day; Philip Coffin MD, Director of Substance Use Research for the San Francisco Department of Public Health discusses why our bodies react the way they do to an excess of opiates, the cost effectiveness of narcan and where science needs to head next; and a conversation about the nature of experiencing and dealing with an overdose.