Judithe Hernández first won acclaim as a member of the celebrated Chicano artist collective Los Four. The collective would become a major force in the Chicano Art Movement and the first Chicano artists to break through the mainstream museum barrier. After graduating from Otis Art Institute in 1974, her inclusion in museum and gallery exhibitions in California began immediately with landmark exhibitions at the Oakland Museum and the San Francisco Museum of Modern Art.

Judithe and Carlos Almaraz earned recognition as muralists during the renowned Los Angeles mural renaissance of the 1970's. Together they painted murals for labor rights leader Cesar Chavez and the United Farm Workers Union, as well as community murals throughout Los Angeles.

Over her 52-year career, Judithe has established a significant record of exhibition and acquisition of her work by major public institutions and private collections. Judithe’s artistic presence returned to downtown Los Angeles in 2020 when her seven-story mural “La Nueva Reina de Los Angeles” was installed at La Plaza Village near Downtown Los Angeles.