Professor Marion Campbell is a world renowned statistician, trialist and methodologist. In this podcast, she describes her career working in clinical research, how research has changed during her career, and the launch of a collaboration with

Clinician Educator Incubator program

Jan 29th, 2024 21m 23s

Clinical medicine has always been taught with a strong emphasis on the master-apprentice model. This relies heavily on clinical educators, many of whom give their time freely.However, many do so without any formal instruction in education and

Oesophageal manometry

Sep 18th, 2023 26m 45s

Mechanical ventilation is indeed a lifesaving intervention. However, it is clear that positive pressure ventilation itself has the potential to cause harm. Novel approaches to ventilation aim to minimise this risk, and one such strategy is th

Weaning induced pulmonary oedema (WIPO)

Jul 31st, 2023 16m 8s

If you’ve worked in ICU for very long, you’ll recognise the scenario where a patient who is weaning from mechanical ventilation goes into pulmonary oedema. This syndrome is referred to as weaning induced pulmonary oedema, or WIPO.Dr Rui Shi c

TAME

Jul 17th, 2023 18m 1s

The ultimate outcome for patients who are resuscitated from cardiac arrest depends heavily on the neurological damage that results from a low flow state. Prevention of further damage during this phase is one of the core goals of post resuscita

eCPR and the SHERPA trial

Apr 18th, 2023 11m 4s

This podcast comes to you from the 2023 ANZICS Clinical Trials Group Noosa meeting.ECMO (extracorporeal membrane oxygenation) is steadily embedding itself into modern critical care medicine. Does it have a role in pre-hospital setting for pa

Dexmedetomidine for NIV

Apr 7th, 2023 19m 12s

Non invasive ventilation is steadily establishing itself as a crucial component of the critical care armoury. While many patients can tolerate it, some require sedation.Wisam Al-Bassam is a staff specialist at Monash Medical center and Victor

Fluids in DKA

Mar 26th, 2023 13m 33s

DKA causes a serious disturbance of fluid and electrolyte balance.However, it is said that more complications are caused by our management than by the disease itself. This is no more apparent than in our management of the patient's fluids.Pro

DIC

Mar 14th, 2023 21m 36s

This podcast comes to you from the 2022 LIVES Conference in ParisDisseminiated intravascular coagulation is the endpoint of a range of different conditions, including sepsis. How does this important clinical condition evolve, and what can we

Logical

Mar 12th, 2023 35m 24s

Cardiac arrest causes neurological injury through a sustained period of hypoxia and ischaemia. It has long been thought that avoiding further hypoxia could save vulnerable brain tissue, leading to the common practice of deliberate hyperoxygena

Driving pressures in Acute respiratory failure

Mar 9th, 2023 14m 12s

This podcast comes to you from the 25th Annual Noosa meeting of the ANZICS Clinical Trials Group.It is now well recognised that mechanical ventilation, while potentially lifesaving, also causes damage to the lung in its own right. Careful set

Are cardiac arrest outcomes improving?

Mar 7th, 2023 18m 41s

This podcast comes to you from the 2022 LIVES Conference in ParisSudden cardiac arrest in the community has historically had a poor prognosis. Improvements in prehospital care and post resuscitation interventions have raised hopes that overal

Trauma Induced Coagulopathy

Feb 10th, 2023 20m 14s

Managing bleeding in a patient with severe trauma is a complex process, with multiple interventions occurring in parallel.Derek Kleinveld is an anesthesiology resident at the Erasmus MC in Rotterdam, The Netherlands, and a post-doc researcher

Nutrition in survivors of critical illness

Dec 12th, 2022 32m 27s

There has been an intense focus on the nutritional needs of ICU patients in recent years, but what happens to them when they go to the wards?This important question is now the subject of interest for highly regarded critical care dietitians and

TEAM

Dec 7th, 2022 35m 25s

It is well known that critical illness often features a pro-catabolic state, which can lead to muscle atropy and long term functional deficits. Early mobilisation has been thought to slow the rate of muscle loss, and potentially improve these

AKI in trauma

Nov 30th, 2022 17m 43s

How important is AKI in trauma? Can we predict which patients will be affected? What can we do to stop it?These questions and many more have troubled intensive care clinicians as they care for patients after severe trauma. Dr Anatole Harroi

Ventilation in TBI

Nov 16th, 2022 18m 58s

In traumatic brain injury, the lung and the brain are caught in a complex interplay, where the challenges of managing one can affect the other.Chiara Robba is a consultant in Neuro and General Intensive Care at Policlinico San Martino, Genova.

Patient induced lung injury

Nov 13th, 2022 21m 6s

Ventilation is known to cause injury to the lungs in its own right, but now it is becoming clear that the respiratory effort of the patient may also contribute to ongoing pulmonary damage.Antonio Pesenti joins Todd to discuss what we know, and

SuDDICU final

Oct 26th, 2022 36m 11s

The SuDDICU trial is now in print. This long awaited trial explored the merits of Selective Digestive Decontamination (SDD), and in parallel studied its potential impact on the local microbiology resistance patterns.After over 15 years of wor

Cardiac injury in COVID-19

Oct 14th, 2022 16m 48s

COVID-19 is a multisystem disease, and cardiac injury has been identified as a major contributor to the pathology.Antoine Vieillard-Baron is an intensivist and researcher from Boulogne in France, and he joins the podcast to talk about key echo

Thrombotic microangiopathy

Sep 13th, 2022 35m 7s

Thrombotic microangiopathies are uncommon disorders, and can result in significant patient morbidity. With the introduction of effective new therapies, the outlook for those suffering from these diseases is increasingly optimistic.Elie Azoula

Preventing sternotomy infections

Sep 6th, 2022 18m 21s

Surgical site infections are a dreaded complication of all surgery, no more so than in cardiothoracics. Antibiotics at the time of surgery has an established role in the prevention of infections, but the duration of therapy remains contentious

Fluid responsiveness

Sep 1st, 2022 17m 13s

Does my patient need bolus IV crystalloid fluids?This is a conundrum faced on a daily basis for clinicians working in the ICU. As time goes by, more evidence of the harm fluids do becomes available, so how can we be sure the fluids we give ben

Antimicrobial stewardship

Aug 23rd, 2022 19m 16s

The development of antimicrobial agents is one of the most influential achievements of modern medicine. However, where once we thought the days of sepsis deaths could be numbered, antimicrobial resistance has given us pause for pessimism.Profe

Thrombolysis in ARDS

Jul 13th, 2022 22m 41s

The pathophysiology of ARDS is complex and remains incompletely understood. However, it is clear that ARDS is not simply a disease of the alveoli.Understanding the pathological basis of ARDS will assist in the development of new therapies for