This week, Christina and Jamie discuss the importance of not holding things in, the stages of grief, finding people to lean on, and more.Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison BresnickAudio Engineer: Josh Wi

Jennifer Esposito

9 days ago 1h 5m

This week, Christina and Jamie are joined by Jennifer Esposito. Jennifer opens up about her celiac disease and the struggle she went through to get a diagnosis. They also discuss the gaslighting of women, the importance of fighting for your hea

You Get What You Give

16 days ago 53m 53s

This week, Christina and Jamie discuss feeling trapped, missing high heels, their favorite shows that they’ve worked on, and more.This episode was recorded in early 2024.Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison

Katie Couric

23 days ago 1h 12m

This week, Christina and Jamie are joined by Katie Couric. They discuss the importance of community and honesty, why we need more collaboration over competition, the changing media landscape, and more. Executive Producers: Christina Applegate,

Jean Smart

30 days ago 57m

This week, Christina and Jamie are joined by Jean Smart. They share memories from when Christina and Jean worked together, and discuss taking back your power, embracing the quiet moments, her career trajectory, and much more.Executive Produce

Body Talk

May 14th, 2024 55m 57s

This week, Christina and Jamie open up about their battles with eating disorders and self-esteem. They reflect on the moments that changed their lives, and discuss body dysmorphia, societal conditioning, how they each got to a healthier place,

How Did You Know?

May 7th, 2024 1h 5m

This week, Christina and Jamie discuss giving up control, feeling judgement, and Jamie shares how she knew to get tested for MS. They also answer some listener questions.Parts of this episode were recorded in 2023.Executive Producers: Christi

Jimmy Kimmel

Apr 30th, 2024 53m 15s

This week, Christina and Jamie are joined by their friend, Jimmy Kimmel. They discuss finding humor in tough situations, the things he still wants to accomplish, speaking from your heart, mean tweets, and much more.Executive Producers: Christ

Can I Be Honest?

Apr 23rd, 2024 48m 57s

This week, Christina and Jamie discuss feeling obligated to be strong, the importance of being there for each other, wearing diapers, and much more. They also answer some listener questions.Parts of this episode were recorded in 2023.Executi

Martin Short

Apr 16th, 2024 1h 7m

This week, Christina and Jamie are joined by Christina's friend, the one and only Martin Short. They reminisce about working together, share funny stories, discuss colonoscopy parties, and much more.Executive Producers: Christina Applegate, J

It’s Okay to Be the Caboose

Apr 9th, 2024 49m 53s

This week, Christina and Jamie discuss traveling, the feeling of being a burden, the importance of listening to your body, and more. They also answer some listener questions.Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Alli

The Power of Now

Apr 2nd, 2024 57m 45s

This week, Christina and Jamie discuss the importance of being honest about how they're feeling, their love of New York, how to be less hard on themselves, and more. They also answer some listener questions.Executive Producers: Christina Appl

Edie Falco

Mar 26th, 2024 50m 19s

This week, Christina and Jamie are joined by Edie Falco, who starred on "The Sopranos" with Jamie. They share their perceptions of each other while working on the show, and discuss parenting, cancer, the importance of being vulnerable, and more

How Are You?

Mar 19th, 2024 45m 17s

On the first episode of MeSsy, Christina and Jamie share how they became friends and what they've learned from each other. They also discuss the importance of setting boundaries, how they've learned to handle doubt, and much more.Executive P

Trailer

Introducing: MeSsy

Mar 4th, 2024 1m 13s

Christina Applegate and Jamie-Lynn Sigler are getting vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilar

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