Most people enjoy the occasional drink, but what happens when it goes too far? Anne Lingford-Hughes is an addiction psychiatrist at Imperial College London who works on alcohol and heroin addiction. Using imaging techniques, she studies the inhibitory pathways in the brain that may be abnormal in addicts, and investigates memory and other cognitive functions that can be affected by chronic use of alcohol and heroin. Join her to hear about the complex mechanisms that underlie addiction, treatment and relapse.