Earlier this week, results from the HYPERION trial were published in the New England Journal of Medicine. Drs. Abella and Teran discuss the use of TTM for patients resuscitated from cardiac arrest with a non-shockable initial rhythm.

Suggested Readings:

1. Lascarrou JB et at., “Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm.” N Engl J Med. 2019 Oct 2.https://www.ncbi.nlm.nih.gov/pubmed/31577396
2. Perman SM et al., “The Utility of Therapeutic Hypothermia for Post-Cardiac Arrest Syndrome Patients With an Initial Nonshockable Rhythm.” Circulation. 2015 Dec 1;132(22):2146-51. https://www.ncbi.nlm.nih.gov/pubmed/26572795
3. Grossestreuer AV et al., “Magnitude of temperature elevation is associated with neurologic and survival outcomes in resuscitated cardiac arrest patients with postrewarming pyrexia.” J Crit Care. 2017 Apr;38:78-83. https://www.ncbi.nlm.nih.gov/pubmed/27866109
4. Neilsen N et al., “Targeted temperature management at 33°C versus 36°C after cardiac arrest.” N Engl J Med. 2013 Dec 5;369(23):2197-206.https://www.ncbi.nlm.nih.gov/pubmed/24237006