Dr. David Holtzman is the Andrew B. and Gretchen P. Jones Professor and Chairman of Neurology, Professor of Developmental Biology, Associate Director of the Alzheimer’s Disease Research Center, and a Head of the Hope Center for Neurological Disorders at Washington University in St. Louis. Much of the research in David’s lab is dedicated to better understanding the mechanisms underlying neurodegeneration, particularly looking at mechanisms and biomarkers of Alzheimer’s disease. In his free time, David loves playing tennis, road bicycling, hiking, going to vineyards, and traveling. He particularly enjoys exploring the culture of different places while traveling with his wife. David received his Medical Degree from Northwestern University and completed Residency in Neurology at the University of California, San Francisco. David has received many awards and honors during his career, including a Paul Beeson Physician Faculty Scholar Award in Aging Research, the Potamkin Prize from the American Academy of Neurology for research on Alzheimer’s disease, a MERIT award from the National Institute on Aging, the MetLife Award for research on Alzheimer’s disease, and two of his research discoveries were listed in the top 50 scientific innovations in 2006 by Scientific American. He is also an elected member of the American Neurological Association, the American Society for Clinical Investigation, and the Institute of Medicine of the National Academy of Sciences. In our interview, David tells us more about his life and research.