Plus Three dives deep into the world of drugs, from local decriminalization and emerging psychedelic corporations to leftist politics and mass incarceration. Each week the team and guests attempt to make sense of the complex connections between drugs, science, capitalism, policy, and culture.

The podcast is co-hosted by Psymposia co-founder Brian Normand, psychedelics research and bio-ethicist Nese Devenot, evolutionary ecologist Brian Pace, and underground researcher David Nickles.