In this podcast series we focus on key topics in healthcare simulation education. The first several podcasts focus on the book, Comprehensive Healthcare Simulation: Mastery Learning in Health Professions Education, published by the Northwestern Simulation team in 2020. Dr. Jeffrey Barsuk leads the discussions by highlighting key issues about principles and practices of simulation-based mastery learning with chapter authors and book editors. Subsequent podcasts discuss key issues in healthcare simulation with experts in the field. Podcast listeners should feel free to reach out to the Northwestern Simulation team via email at: [email protected].