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Data Science Cloud Lessons at Scale

Data Science Cloud Lessons at Scale

Released Thursday, 18th September 2025
Good episode? Give it some love!
Data Science Cloud Lessons at Scale

Data Science Cloud Lessons at Scale

Data Science Cloud Lessons at Scale

Data Science Cloud Lessons at Scale

Thursday, 18th September 2025
Good episode? Give it some love!
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Today on Talk Python: What really happens when your data work outgrows your laptop. Matthew Rocklin, creator of Dask and cofounder of Coiled, and Nat Tabris a staff software engineer at Coiled join me to unpack the messy truth of cloud-scale Python. During the episode we actually spin up a 1,000 core cluster from a notebook, twice! We also discuss picking between pandas and Polars, when GPUs help, and how to avoid surprise bills. Real lessons, real tradeoffs, shared by people who have built this stuff. Stick around.

Episode sponsors

Seer: AI Debugging, Code TALKPYTHON
Talk Python Courses

Links from the show

Matthew Rocklin: @mrocklin
Nat Tabris: tabris.us

Dask: dask.org
Coiled: coiled.io
Watch this episode on YouTube: youtube.com
Episode #519 deep-dive: talkpython.fm/519
Episode transcripts: talkpython.fm
Developer Rap Theme Song: Served in a Flask: talkpython.fm/flasksong

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