On this episode of Pandemic Proof, Dr. Ayoade Alakija, the World Health Organization’s Special Envoy for the Access to COVID-19 Tools Accelerator (ACT-A) and co-chair of the African Union’s African Vaccine Delivery Alliance, joins Javier Guzman to discuss global cooperation during health emergencies. Together they reflect on the role of ACT-A in facilitating the development of and equitable access to medical countermeasures during the COVID-19 pandemic; highlight advantages and disadvantages of regional initiatives; and call for a truly representative global health system.