0:00

What a team! It's Episode Three Hundred

0:02

and seventy eight of the Genius Life.

0:04

Let's go. Man.

0:12

Hear. What?

0:17

The Genius lush. What's

0:23

going on? Everybody welcome back to another episode

0:25

of the show. I'm your Host Max Luke

0:27

of your a filmmaker, health and science journalist

0:29

in New York Times best selling author. I've

0:32

dedicated my life to unraveling the science behind

0:34

our choices, including what we eat and how

0:36

we live, affect our cognitive and physical performance,

0:38

how we feel our health span and are

0:40

risk for disease. This podcast is all about

0:42

how to live in that optimal state which

0:45

I call living like a genius on today's

0:47

episode of the show. I'm super excited to

0:49

welcome back for the second time. My friend

0:51

Doctor Lisa Moscone Lisa is. An associate professor

0:53

of Neuroscience in Neurology and Radiology at

0:56

Weill, Cornell Or Medicine and she's a

0:58

director of the Women's Brain Initiative and

1:00

the Alzheimer's Prevention Clinic at Weill Cornell

1:02

Medicine New York Presbyterian Hospital. She's a

1:05

Water Now neuroscientist with a Phd in

1:07

Neuroscience and Nuclear Medicine from University of

1:09

Florence and Italy, and she's the New

1:11

York Times bestselling author of the X

1:13

X Brain, a guide for women to

1:16

protect their bodies and minds to ensure

1:18

their brains remain resilient throughout their lives.

1:20

On today's episode of the show, we're

1:22

Going. To discuss all things dementia prevention

1:24

and we're going to touch on the

1:26

subject of her latest book, The Menopause

1:29

Brain New Signs empowers women to navigate

1:31

the pivotal transition with knowledge and confidence

1:33

of a long time fan of Lisa,

1:35

Doctor Moscone and she actually is a

1:37

featured interviewee and my upcoming documentary Little

1:39

Empty Boxes. That's how big of a

1:41

supporter I am of her work. So

1:43

listen through all the way to the

1:45

end and share this episode of Friends

1:47

and Loved Ones that you think may

1:50

benefit from it. I'm down in Mexico

1:52

where I came. For a speaking gig

1:54

along with some regenerative medicine treatments

1:56

which I'll be sharing the details

1:58

of on my. Instagram and here

2:01

and the podcast I'm sure and

2:03

later dates. but ah, In

2:05

any case is was a think you guys

2:07

for listening. For staying subscribe to the show

2:09

we've got lots of very exciting episode in

2:11

a can. I'm super pumped. Ah to get

2:13

these out to you and if you haven't

2:15

yet, please consider leaving a rating and review

2:17

for the show on your podcast app of

2:19

choice. It's a freeway to supports what we're

2:21

doing here at the Genius Life. It takes

2:23

seconds to do and it does help us

2:25

grow so thank you again. And now with

2:27

all that out of the way, here's my

2:29

conversation with the great Doctor Lisa Moscone covering

2:31

all things dementia prevention for both men and

2:33

women. Here we go. Lisa Moscone what's

2:35

going on will come back to the

2:38

so thin amiss it's been three years.

2:40

I now crazy. We did it at

2:42

the beginning of Cove Edwards reflecting for

2:44

said rolling via Skype or something hyped

2:46

by Ah, but we've actually known each

2:48

other for many years. You are an

2:50

interviewee and my upcoming documentary on Like

2:53

Boxes which I'm super excited about and

2:55

dumb we've got a lot of ground

2:57

to cover his you are. You become

2:59

an incredibly prolific researcher. I love your

3:01

work, it's own powering, so. What?

3:03

Are the top three ways to

3:05

build an Alzheimer's resistant brain and

3:08

avoid cognitive decline. In

3:10

a the it. says. Question.

3:13

Answered the pot three. Ways.

3:17

Would. Be. One.

3:19

Too many. It's all on

3:22

existing conditions and medical conditions

3:24

that could negatively impacting health.

3:28

The. Keel on, say Hi

3:30

to see metabolic disorder, state

3:32

diabetes, and obesity, sire diseases

3:35

a big one and. They

3:38

would be my number one day. So many

3:40

other things to come to The peach Ireland

3:42

you try to manage distinguish and some I

3:44

think the cuticle ways the some as is

3:46

nice time and is a case in some

3:48

number two would be like ten adjustments. whom.

3:51

And. For every person in depends on

3:54

the specific risks, the Uk, my

3:56

desk and people who eat extremely

3:58

health delete the nether. By

4:01

order of people who exercise and sleep house to

4:03

the but have a huge amount of street. In.

4:06

Their life service a target

4:08

your lifestyle trigger. A

4:11

number three specifically for women,

4:13

manage men oppose. Regenerate,

4:16

And to talk about a little

4:19

bit more and a minute. but

4:21

it turns out that hormonal changes

4:23

summit lice may be triggers for

4:25

an increased risk of Alzheimer's disease

4:28

in late lies and is changes

4:30

could be mitigated and list for

4:32

some women by intervening and trying

4:34

to restore one one at levels

4:37

which is an interesting neil. Attractive.

4:40

Way of reducing Alzheimer's disease from the

4:42

get go. He was a interesting that.

4:45

Super interesting sights on a recap. So

4:47

yeah that does or does it vary

4:49

of drought and yeah no but I

4:51

but I love it. A lot of

4:53

seated in this topic in your really

4:55

a pioneer in the field so I

4:57

think this is incredibly valuable to one

4:59

manage preexisting like medical conditions I might

5:01

be negatively impacting your brain health. Yes

5:03

he can see you can get some each.

5:06

Indeed, Act. Those said it acts

5:08

damage from think they would don't

5:10

usually associate with brain held by

5:13

by We know that the health

5:15

of your heart is related to

5:17

the health of your brain. The

5:19

health of your hormones is related

5:21

to the health of your brown.

5:23

Your cardiovascular respiratory health is related

5:26

to your brain. How's that Inflammatory

5:28

conditions negatively impact your brain? So

5:30

does. There are things that we

5:32

we all my want to really

5:34

take into account and work. To. Manage

5:37

and minimize the impact of and

5:39

dose of prevent For those who

5:41

don't have any a disc conditions

5:43

to think it's really important to

5:45

try and avoid developing. Any.

5:47

Otoh and we had a change in

5:49

in. I did risks that can come

5:51

into play genetics. Yeah for public health

5:53

standpoint, load you sir the most pressing

5:55

conditions that are putting. Probably.

5:58

More people at risk today that. Maybe

6:00

couple decades ago. Senate about

6:02

it. Sylar, there's there's such

6:05

a huge increase in conditions

6:07

like diabetes pre diabetes, insulin

6:09

resistance, and overweight. even if

6:11

you don't meet clinical criteria

6:14

for obesity, In. Have been.

6:17

Consistently. Overweight is also

6:19

a factor of for dyslipidemia

6:21

and inflammatory conditions, the cardiovascular

6:24

conditions, and potentially for neuro

6:26

vascular conditions that are in

6:29

turn a factor for alzheimer's

6:31

and dementia. Very.

6:34

Interesting. Connected. And

6:36

to see like. Sometimes.

6:38

Working in a Western medicine. Environment

6:42

and approach feels slightly

6:44

frustrating. Slyly. Because

6:47

we are several compartmentalize,

6:51

That are scope of work

6:53

as nut allergies can bring

6:55

specialists. Can. Not. Really?

6:59

Get it to somebody as this territory

7:01

and so is quite limited but a

7:04

a really strongly believe the integrate have

7:06

helped is the way to go for

7:08

everybody works together and we tree I

7:11

should we call manage. In.

7:13

Taking care of that one person.

7:15

Not Oregon By Oregon. The.

7:18

Starting with the person and and

7:20

bringing and expertise. The. Target defend

7:22

risks and different conditions with doesn't make

7:24

sense. Yeah, you've always been

7:26

so progressive in that regard. Like

7:29

Krugman. among your for the your

7:31

first book you talked about water

7:33

quality. I got it and I

7:36

was. Not expected to become

7:38

such a thing. Now people talk

7:40

about it is water be really

7:42

good for brand health and that

7:45

not all was it is water.

7:47

Say. A I just said you won so

7:49

many with you edges sooner. Your brain doesn't

7:52

just want something wet. It

7:54

wants fluids to come with electrolytes and

7:56

nutrients. To their support they were hydration

7:58

but also they're not ashamed. Your brain

8:00

cells because. No. Chemical Reaction

8:02

kennel quarter inside your brain alleged to

8:05

have voices to power it union the

8:07

as any, the hydrogen and you need

8:09

the oxygen that comes from the fluids

8:11

and for me was such an obvious

8:14

stay. And then became a

8:16

bit of a D based in of the

8:18

other purify. it was her best soda Help

8:20

ourselves. In South

8:22

In wonderland. No success.

8:26

Was I am on social media today. Says

8:29

on the answers are made a dozen. I thought I

8:31

like a battle cry there. For me to

8:33

the any to take assigned yeah I you had

8:35

to either be in or out and then. That

8:38

I heard you're eating a little bit

8:40

of oats and sweet potatoes. You never

8:43

know because I feel like when

8:45

we first met they allow us

8:47

when we first met you probably

8:49

I was I think you probably

8:51

very cisa eras year early cheeto?

8:53

Yeah right. Yes, I

8:55

was definitely like very interested in it.

8:57

I don't know if I use Yeah,

8:59

I definitely. I was avoiding. Any

9:02

the chorus and kites and. Yeah,

9:04

very long carbs an arm

9:06

but I've of, I've changed

9:08

my thinking because now it's

9:10

I feel that whatever we

9:12

can do to hum. Increase

9:15

our fitness, I.

9:17

Think that's really important and I

9:19

think insofar as carbohydrates are of.

9:22

Obvious. On performance

9:24

enhancing tool when resistance training

9:26

among other things, I think

9:28

they're. Super. Useful. So this whole

9:30

idea of you've gotta be in Cheetos is

9:33

also I mean I think and and correct

9:35

me or are you know, please chime in

9:37

if you feel differently. But I think from

9:39

a therapeutic standpoint the kid agenda guy to

9:41

still very interesting. Very important needs to be

9:43

studied. but as a preventative diet, there's no

9:45

No, there's no need to be on a

9:47

kitchen and nine as a preventative, it's against

9:49

therapeutic diet. The first. some

9:51

conditions like a potentially he adds

9:53

essentially it does kind seats. It's

9:55

a catch. Twenty two. Because

9:58

did research has not been done. Who.

10:00

Like you said, there's no strong

10:03

evidence to teaches any diet might

10:05

work preventatively rep, but there's no

10:07

strong evidence. Tickets tried, no studies

10:09

give really looked into it. So.

10:13

I've never been a big. Fan.

10:15

Of to touch any diet during your your

10:17

italian has. Also.

10:20

Some a really really wrong if you

10:23

are a proponent of Tito being Italian,

10:25

Us and the vegetate me. That's

10:29

the my highest point in our a

10:31

say in brain food. It was never

10:33

about supporting when diet over the either.

10:35

It was always about explaining what kinds

10:38

of suits Inuit fans have been shown

10:40

to really support brain health and done

10:42

it's your choice. With.

10:44

As a diet look for you. Great

10:47

says make sure I do. You have

10:49

enough the does nutrients in that new

10:51

trend and think about it. In.

10:53

Terms of Brain: how does well as

10:55

seat nansen, muscle mass and cardiovascular seen

10:57

that so. I in.

11:00

There's one thing that I have. Some

11:02

working with people for decades a stand.

11:05

Nobody wants to hear that their diet

11:07

is not rational her scarf or at

11:09

the snow and say i say them

11:11

the best the best solutions just to

11:13

provide the information and then make sure

11:15

they your toys is based on facts

11:18

and knowledge Ended it really works for

11:20

you in a sustainable and then if

11:22

there's any need to change your diet

11:24

and we were together and we will

11:26

change it if need be. right?

11:29

So I think that testing is very important.

11:32

We do nutrients. Lamps as

11:34

well to make sure that you know like

11:36

you meet your. Intake.

11:39

Or levels of antioxidants for example. There's

11:41

no heavy metals they have I'm sure

11:43

you have on the floating in it

11:46

at Other people have enough protein and

11:48

enough for did healthy fats. And once

11:50

you meet your standards in your goals

11:52

than you know you you eat. Twist

11:55

he will you get I'm I'm right there with

11:57

you. There are many ways up. mm. May.

12:00

Have an undersized film center you posted.

12:03

His son was so smart. That is

12:05

really about common sense. You

12:07

know as long as one avoids processed

12:09

foods and price on the Tory foods

12:12

and fast foods and on this was

12:14

the we know to be really bad

12:16

for you in the fuck is this

12:18

on whole suits and you eating ass

12:20

of fiber in fighter know she ends

12:23

in vitamins and minerals then you're basically

12:25

on the right track right now. we

12:27

can optimize. But. It

12:29

kinda just John Bolton. And

12:32

ended choices. And but I you say

12:34

and you want to diversify because diversity.

12:36

Is key to jump through it and also

12:39

in the past. Handful

12:41

of years, The. Nefarious.

12:44

Role that autre processed foods play in

12:47

metabolic health. brain health have really come

12:49

into the spotlight in a way that

12:51

you know when we first connected, I

12:53

don't think the doubling was really well

12:55

established. You. Know, I think a lot of people

12:57

do not believe it. And. A sign

12:59

who had to clean his and suddenly

13:01

the been skeptical. About.

13:03

Any findings that relate. Diet.

13:07

And exercise and we're not

13:09

to health especially brain health

13:11

and they seem to last

13:13

may decide to six years

13:15

has seen so many studies

13:18

consistently showing a harmfulness fact

13:20

that is now accepted, the

13:22

certain chemicals included in processes

13:24

and all the price. Laboratory.

13:27

Components. Are processed. Foods

13:29

can be harmful for Britain. How

13:31

do you see? the new Lancet

13:33

Commission guidelines? Know. If

13:36

pollution. Oh. Yeah, I from twenty twenty.

13:38

Twenty twenty Years and is. Something

13:41

else Take him out and twenty twenty two

13:43

along those lines to watch a second and

13:45

on shown in the air pollution is the

13:48

second they considered and we thank you for

13:50

not signing disease. But then if you read

13:52

inside the subsection deals to talk about pollutants

13:54

in general. So I think maybe in the

13:57

next forty years when good revised again it

13:59

might include. Environmental toxins.

14:02

More like is a broader

14:04

category. Yeah, earlier this year

14:06

we have to. We have to. Yeah,

14:11

This. Episode: The show is sponsored by

14:13

All I force my favorite at Home

14:16

lab testing solution after lie for sent

14:18

a phlebotomist over my house to do

14:20

their baseline lab work every couple of

14:23

months. I've subsequently retested in part because

14:25

Why For simply makes it so easy

14:27

they just send somebody over my house,

14:29

they draw blood and then based on

14:32

their rigorous biomarker testing they provide functional

14:34

medicine, doctors, certified health coaches, and Advanced

14:36

Nutraceutical and hormone therapy is based on

14:39

my lab results You don't want to

14:41

play. Russian Roulette with your health

14:43

and if your diet and lifestyle

14:45

isn't working for you, Life Force

14:48

can help identify blind spot and

14:50

help set you off down the

14:52

right path. It's health optimization made

14:54

easy and for my audience. If

14:57

you had to my Life force.com

14:59

and use code Genius or you'll

15:01

get fifteen percent off Again, that

15:04

is my Life force.com spelled Myliseforce

15:06

dot Com and again use Could

15:08

Genius to get fifteen percent off.

15:10

Don't guess. Test and had to my

15:13

Life force.com today and again use Code

15:15

Genius for fifteen percent off. Enjoy! We

15:17

you and you. You've always been so

15:19

ahead of the curve. I want to

15:21

go off on to farm attention but

15:23

we just had some raid. Dorsey on

15:26

the show who talks about air pollution

15:28

in the context of persons disease? Yes,

15:30

insane, didn't mind blowing. I'm. By.

15:32

Yeah, well. what proportion

15:34

of. Dementia.

15:37

Cases. Do you think

15:39

are preventable. It

15:41

depends. industry is some studies state

15:43

use populists and population based estimates

15:46

betrayed the ones I prefer because

15:48

they're based on that. they have

15:50

ended in projections and you can

15:52

check the stats and you know

15:55

exactly which studies it being included

15:57

in Med. I know this isn't.

16:01

I would say the most

16:03

conservative estimates I had seen

16:05

his twenty percent. And

16:08

him as generous as seen sixty.

16:11

So. Forty. Yeah,

16:14

the average. Which is a lot. It's

16:16

a lot of cases and also decisions

16:18

based on data we have raped by.

16:20

does. Lead. Me

16:22

to research looking. At.

16:25

Correlating lifestyle with Alzheimer's disease.

16:27

So as we have more

16:29

studies I have ceiling daddy

16:32

percentage will increase. Get

16:34

out that Lancet commission paper. I think

16:36

forty percent was would they. They

16:39

as a forty percent which

16:41

is based on and conservative

16:43

statistics should get some after

16:46

to the conservative but they

16:48

are a little bit. Ultra.

16:51

Conservatives: In some aspects

16:53

side to steal say we don't have

16:56

enough. Proof. To die it is

16:58

a prevent to see them. I have proof.

17:00

Do you need you know for air pollution

17:02

does may be some studies. Observational

17:05

studies and. We

17:09

have hundreds and thousands probably a

17:11

study many of which showing a

17:13

consistent positive effect of this candidate

17:15

and brain health and the say

17:17

it's just not enough thing while

17:20

for kind of crazy joey using

17:22

here nor can we talk about

17:24

levels of evidence but I think

17:26

will gather. Yeah, One thing that

17:28

stood out to me about that paper

17:31

in particular was that was one of

17:33

the. You know it

17:35

it listed out although the the non

17:37

modifiable risk factors and in the modifiable

17:39

risk factors but among the modifiable risk

17:41

factors I was looking to see if

17:43

they if they are going to talk

17:45

about the role that like is anti

17:47

corner drugs can play and they why

17:49

in there are some and allow both.

17:53

I get some, isn't it mightn't is almost

17:55

as much evidence of them. Footloose and. I

17:57

would say read yeah so. Atheists? arbitrary.

18:00

Yeah on some that, what's that it? You know? We'll.

18:03

Get. Yeah, we'll get there. Okay

18:05

so and then the last of

18:07

soap Step to you said, where

18:09

the lifestyle factors? Yes Ryanair. Quite

18:11

a few to have been consistently

18:13

sound to either improve or harm

18:15

been held an increase in Dixie

18:17

the same it's with Can never

18:19

say the top few would be

18:21

accessing. Snow Everybody

18:23

agrees is probably a number

18:26

one preventative measure against Alzheimer's

18:28

and dementia that everybody agrees

18:30

on delete. Sleep.

18:35

In this is my second to

18:37

about pets. Sleep is definitely important.

18:40

stress reduction. Is. Something

18:42

that's becoming more and more

18:44

at the forefront of preventative

18:46

effort. And

18:48

environmental toxins. Is

18:50

another one and then social

18:53

stimulation. Social. Networking an

18:55

intellectual stimulation in a very specific

18:57

pay that you want to the

18:59

cognitive layering a on together via

19:01

good cognitive stretch to think it's

19:03

an interesting way to put if

19:05

that you want to challenge your

19:07

note. On got it to make. New

19:09

connections and fire. Him

19:13

fiercer. Where it's supposed like you

19:15

want to stimulate your brain to learn?

19:18

Because learning is to your brain

19:20

was exercises to your muscles straight

19:22

is trend since your connections between

19:25

neurons and that increases cognitive reserve.

19:27

And. Cognitive reserve is a

19:30

preventative against dimension dissident

19:32

insult. Wow so cool to

19:34

hear you say that a really really

19:36

made me think of because now in

19:38

the world of fitness there's a lot

19:41

of attention being placed on what's called

19:43

stretch mediated hypertrophy we've heard of us

19:45

News is something that like the all

19:47

like all of meat were all like

19:50

how obsessed with as basically evidence showing

19:52

us a when your muscles are in

19:54

their stretched position under tension. That

19:56

you seem to get a lot of like. So.

20:00

Alice in terms of like muscle growth

20:02

net an accent in the stretched position

20:04

specifically as opposed to the contract and

20:06

position you didn't want to work out

20:08

through a full range of motion, but

20:10

that kind of emphasizing that stressed stretched

20:12

position seems to be really beneficial. like

20:14

a really patterns really powerful signal. To.

20:17

Adapt and grow stronger. And so it's kind

20:19

of interesting or com talking about building this

20:21

cognitive reserve in the same way that when

20:24

the no rain is stretched. When we stretch

20:26

our cognitive you know, muscles. A cinch

20:28

As silly as saying that

20:30

the case that are now

20:32

starting to use this past

20:34

summer and brain imaging technique

20:36

a studies he I decision

20:39

tensor imaging mean that size

20:41

det kang it is stimulation

20:43

and intellectual sickness. If he

20:45

will is correlated with that it

20:47

tensing. Inside. Your brain which

20:49

is kinda what you're saying with Amazon's

20:52

we're We Measure was edition Dvd along

20:54

the cyber is inside gets a brain

20:56

scan. Of do a pleasant I have

20:58

you rangel with my i would love to scan

21:00

on a risk I'm in you know one on

21:02

M yeah I would love to. I think

21:05

have been to see you consider connectivity of

21:07

the abandoned we give you. Delete

21:09

a movie than in an English. And is

21:11

just sounds so cool. The

21:13

so we do a deity eye scans

21:15

that a treaty high resolution Dc I

21:17

wish this again is diffusion tensor imaging

21:19

with would measure and the way the

21:21

water flows. Through the

21:23

cyber or dinner and you want your

21:26

friend is to be. Straight.

21:29

Great. Because you want you know tends to be. Nice

21:32

thick London lean in the late

21:34

Just Betty. There's any deviation of

21:36

any and Clarkson said insurance than

21:38

divorce or cannot issues. Seeley. Nbc.

21:41

Deviations in a prominent discuss Saxena Annie

21:44

such repeat we would measure if you

21:46

if you until we could do it.

21:48

And. Your brand and yeah, think

21:50

it's really cool in New York? No

21:53

idea why did. They have to do that I use of

21:55

com I do. It amazing of

21:57

superdome com. See.

21:59

Know they had. Here are five

22:01

hundred participants. My. Gosh,

22:03

financing Wow. So cool you.

22:06

I love that! They've.

22:08

Come a long way when we first met your

22:10

and why you price yes a ride. My Steiner

22:12

ear and amway your medical in

22:15

remember when my ossetia and you

22:17

may be a lot of mitochondrial

22:19

it's either not be that guy

22:21

and in the was the first

22:24

time. They. They've and I had

22:26

ever done an interview take. The

22:28

yes if local sake like I guess

22:30

we're going up and how far you

22:32

from your no New York Times bestselling

22:35

author And it's incredible. Sanjana

22:37

recently was twenty six teen hey

22:39

number the his Then I moved

22:41

to pronounce. Love

22:44

it! Yeah, I

22:46

mean the those were early days for the

22:48

field of the mentor prevention were they not?

22:50

They. Are early

22:52

Fitzsimmons originally. Yeah yes him

22:54

when a when he has to

22:56

while covenant Madison to join the

22:58

traits that isaacson the same is

23:00

prevention clinic everybody thought was mad.

23:03

They. Want to use to would

23:05

present cent of thinly and they

23:07

also is that is just of

23:10

advantage that as a kid three

23:12

movies that race creed that says

23:14

who doesn't seem like conservative The

23:16

cylinder could Isaacson last on my

23:18

department as me to take over

23:20

the clinic. Sam now. We

23:23

launched a program is Carlyon same

23:26

as prevention program in includes three

23:28

units. There is my women's training

23:30

he cities which is an observation

23:32

on can use of research study

23:35

daniels him his prevention clinical trials

23:37

unit when they run clinical trials

23:39

have some is prevented that a

23:42

specific to women or men. The

23:44

sex specific and molecules they were

23:47

testing and then just the clinic.

23:49

The semester mentioned Clinic Deadly opens.

23:52

Six. Months ago had billions works

23:54

little differently now that it's

23:57

opening, At. Sir Though,

23:59

like here. Say is it the same

24:01

locations. Center Case and guess them

24:03

were moving soon to a new

24:06

building on Lexington. Look forward to

24:08

that. Yeah, so can you were

24:10

high school here I'm sure. And

24:13

we're gonna have it. seven tesla am

24:15

I right there by the clinic? So.

24:18

Patients. Come in. We give them a

24:21

brain scan and. They don't

24:23

have to go anywhere at everything is just managed.

24:25

On site well. As.

24:27

Stunning as it does the causing ever

24:30

new on can't really game changing into

24:32

so important. Cause. You know

24:34

at once you once you have dementia,

24:36

it's a. It's. Pretty

24:38

bleak, you know. pretty rough.

24:43

You. Guys must know by now that

24:45

I'm a massive fan of college and

24:48

which stays show can actually support Skyn

24:50

health and Appearance. Tendon Health joins Hair

24:52

Nails and so much more. and my

24:54

go to brand is Bob's Naturals. Every

24:57

serving has twenty grams of college in

24:59

which include seven essential amino acids and

25:01

I did a little bit of an

25:03

analysis. I compared Bugs to another leading

25:06

college and Brand and there are higher

25:08

levels of Lucien which is that amino

25:10

acid that important for stimulating muscle protein

25:12

synthesis. About ten. Percent more losing and

25:15

higher levels of glycine which is really

25:17

kind of the money in terms of

25:19

what you take college and for is

25:21

like the guy seemed content and you

25:24

get about ten percent more that as

25:26

well Pressuring bugs is super soluble in

25:28

water, he doesn't clump like other protein

25:30

brands and it comes from sustainably sourced

25:33

grass fed and pasture raised cows in

25:35

southern Brazil. It's Ketone Paleo diet approved.

25:37

Again, super high quality college in that

25:39

benefits join health muscle recovery got health

25:42

hair skin A nails. And more.

25:44

I try to get between ten and twenty

25:46

grams of college in every single day. This

25:48

is just a bad as company and they

25:50

have the best quality college in that I'm

25:52

familiar with. And if you'd like to save

25:54

twenty percent off of anything that Bugs produces,

25:56

are going to do his head over to

25:58

Bob's naturals.com And as. You B

26:01

S Naturals Bugs naturals.com.

26:03

And you go Genius for twenty percent

26:06

off site wide. Again, that is Bob's

26:08

naturals.com Use Code Genius for twenty percent

26:10

off site wide. Check out their college

26:12

and you will be happy that you

26:14

did. So want to build our cognitive

26:16

reserve Army? Sure the we're sleeping or

26:18

sure exercise now I'm and I love

26:20

is already occurs. You know we have

26:22

episodes on the show where we go

26:24

really deep into each team bucket, but

26:26

to have this sort of overarching protocol

26:28

I think is really helpful for people.

26:31

Who. Exercise occur

26:33

at while we're working on it

26:35

and then when it comes to

26:37

the specific how the third part

26:40

mean right? To. The third

26:42

way to build an Alzheimer's resume or understood the

26:44

specific to women are also very specific to your

26:46

work knows his is so incredible to what is

26:48

it a women need Because women are it twice

26:50

the risk as compared to men right? Well

26:53

the as to say the prevalence of

26:55

a tiny disease is created in women

26:57

than men and currently out of every

26:59

three or same his patients to only

27:01

man. That's. Seven

27:03

and Sunday. I think you would appreciate

27:06

Madison. There's. A difference

27:08

between failings and incidence. Where.

27:11

Prevalence is like a cassette. Chance you

27:13

and if I take on the same

27:15

as patients in America today and we

27:17

divide and by gender than. Two.

27:20

Thirds a whim. and when paired

27:22

with so I meant the denizens.

27:24

The incidence And incidences. The rate

27:27

at which people desert a certain

27:29

disease in is more and more

27:31

evidence that women tend to the

27:33

developer same assistance to rates than

27:36

men as well. The nice to

27:38

the women mascot. So.

27:41

It's harder to diagnosed early

27:43

dementia in women many men

27:46

because the clinical tests didn't

27:48

matter. The cognitive neuroscience tests

27:50

the we used to simple.

27:54

In. Some ways in didn't say

27:56

specifically target verbal memory which

27:58

women really I. Great at.

28:00

And I'm not saying that in

28:02

a presumptive. what is just that

28:05

women find it easy. To.

28:08

Do those tests because strengthened

28:10

some subtle differences in cognitive

28:12

skills. They. And

28:14

uses of course is not to stereotype anything

28:17

that manner. Or. Now that it's

28:19

better, we sent a third into a

28:21

visual special. Abilities Women tend to have

28:23

a little bit of an edge when

28:26

it comes to verbal memory and fluency,

28:28

which is specifically what we used to

28:30

diagnose of Simon And so it's silly

28:32

to be harder to say is that

28:35

same is my kind. It impairment is

28:37

else to diagnose may be delayed. And

28:40

then by the time a woman

28:42

is diagnosed the pathologist more severe

28:44

wow and is harder to treat.

28:47

Said. Is better innovating those tests.

28:49

Well, I'm trying to sweets not just

28:51

me, but everybody wants to switch to

28:54

brain imaging. Because. His

28:56

performance independent and we can get of

28:58

really clear sense is what's happening in

29:00

your brain regardless of not regardless of

29:02

whether you not you have seen him.

29:05

Play In. We know that Alzheimer's

29:08

starts in the brain. Years.

29:10

If not decades before were able to

29:12

make a diagnosis and clinical grounds and

29:15

is is tricky because we think of

29:17

us. I mean this the disease of

29:19

old age but in reality it's a

29:21

disease a mid life. With.

29:24

Seen them to start in old age

29:26

feel we want to move to diagnose

29:28

desert. Did the early detection back to

29:31

the need Nice. Years. And.

29:33

The only way to do it is. By.

29:36

Using brain scans. So we do a lot

29:38

brain imaging and men and women with risk

29:40

factors. For us I mean is is like

29:42

having a scammer, the history of Alzheimer's like

29:44

you and me or in a pulley for.

29:47

Genotype. What are the risks? For

29:50

dementia and we do. We

29:52

want to get of really

29:54

good baseline before and one.

29:57

Start forgetting keys or name Sprite.

29:59

You want to have a. The baseline so that it

30:01

saying Ten years, fifteen years from now

30:03

you have an actual issue or concern.

30:05

come back with redo it a brain

30:07

scans and then it's every doctors a

30:10

dream to have a baseline where you

30:12

were fine so I don't have to

30:14

compare you to other people your age

30:16

but I can compare you to you

30:18

when you didn't have an issue. So

30:20

that's why we do with to the

30:22

brain scans that would do over time.

30:25

I love it when people watching this

30:27

listening to this live giant the the

30:29

world sent through a law that they

30:31

can come to us but also if

30:33

they have primary carer there are with

30:35

their primary care physicians or even neurologists

30:37

were and they're in their home town

30:39

today. Go and ask them to establish

30:41

some kind of cognitive baseline. Cs. Cognitive?

30:43

Yes, you can do that. A

30:46

good cognitive evaluation which is helpful.

30:48

It's. A good starting point: You

30:50

cannot currently get brain scan done

30:53

tentatively and that is an indication.

30:55

Wasn't or something it was I believe was called

30:57

the Seeds Test. Scenes from May

31:00

Be Was it from Pan Herbs

31:02

like through some in other states

31:04

has which is like literally printed

31:06

out. It's a fifteen minute at

31:08

home test the can use to establish a baseline

31:10

or something like that. I remember I talked about

31:13

on the doctor Oz showed and point you. And

31:15

are you bring him into your doctor? It's like you draw clock.

31:18

You do all these on the. Have an idea

31:20

and see ya yas! So is

31:22

it? Slide in any mental state.

31:24

Examination of the male cat Dan.

31:26

It's a testament global can't function.

31:30

It's good to have an admin, why

31:32

not? Why not? Pay is just not

31:34

sensitive. Got it? Takes a lot of

31:36

damage that guess seen. An

31:39

illness and a Sage test specific.

31:41

I've been a the and then

31:43

Ceo mark how it three m see

31:45

kind of tests on their patients who

31:47

clearly. Are impaired and

31:49

still scored pretty high. So.

31:53

We're trying to sweets to a

31:55

cognitive bad at a that is more

31:57

sensitive. And. More equalized.

32:00

Kelly. Meaningful.

32:02

Because. It really depends on the from your

32:05

environment for issue you if you do numbers

32:07

all day long and they give your number

32:09

test of going to be too easy for

32:11

you so you have to be tailored to

32:13

the individual Islam and I don't I don't

32:15

do Canada testing a new brand can. Press.

32:18

By which are better, do it

32:20

again because I get more objective

32:23

biomarkers really. As you get biological my

32:25

case of like he should come and

32:27

get your brain scans we can do

32:29

and i seven difference and what I

32:31

sequences and forty five minutes. Yes,

32:34

where we look a volume. We.

32:36

Load cat atrophied the satellite neuron a loss

32:38

for look at inflammation will look ugly Oh

32:40

is it Will look at find the tracking

32:42

will look at this is he This he

32:44

will look at energy metabolism and will look

32:47

and blood. On

32:49

a forty five minutes and if you let me with

32:51

us to do another type of grass can't and looks

32:53

at the same as plaques. That's. A

32:55

lot of information that you're gathering. It's

32:57

a line from his ah yes. Well what's the

32:59

and wasn't gonna go. The

33:01

first one is a say three

33:03

different types of and eye scans

33:06

Magnetic resonance imaging so devalue metrics

33:08

or done with standard am I

33:10

I I read Agatha. This blood

33:12

flow is measured using a technique

33:14

called a and as tedious pin

33:17

labeling a cell and it on

33:19

Atp production, mitochondria production in the

33:21

brain we can measure It will

33:23

run into issues centers in the

33:25

United States that I'm aware of

33:27

that has been the machine is

33:30

Petrushka P. M S

33:32

Magnetic resonance spectroscopy with a special

33:34

coil the looks of phosphorus to

33:36

the one. So. He can

33:38

measure the first for deletion rates into

33:40

a T P. and Atp is the

33:42

energy currency of ourselves, so it's effectively

33:44

what you want to measure. It's how

33:46

much Atp is your brain producing oil

33:48

your muscles that will do thanks. So

33:51

much around that. yeah, it takes forty five

33:54

minutes that we do a little break in

33:56

between sets. A little bit of an. Hour

33:58

That's a cool thing. Okay,

34:01

so women. Now do we have

34:03

established a them A complete nerd. Really?

34:07

Love it was of it. So what are women do?

34:10

So we would benefit

34:12

from me many. Like

34:14

up to Syria. We.

34:18

I'm with benefit some many of.

34:20

The. Things we discussed for sure

34:22

we the specific focus on metabolic

34:25

and hood wanna help to sit

34:27

one. If you use

34:29

this precision medicine approach that I

34:31

think is the way to guys

34:34

more individualized and more I takes

34:36

into account by your individuality episode

34:38

implement then he looks like men

34:40

and women full of a slightly

34:43

different pathways to alzheimer's disease and

34:45

dementia. So for men. Is

34:47

that in broad audience the let's say

34:50

for men are is more a cardiovascular.

34:53

Route So if you have

34:55

cardiovascular risk so issues dad

34:57

is. Men

35:00

are more vulnerable to that price.

35:02

It's a stronger risk factor for

35:04

man, whereas from for women to

35:07

promise of more metabolic and hormonal.

35:10

To. Death so we're trying to address.

35:12

so I doing died. You shift

35:14

your focus a little bit on

35:16

things that balance your hormones as

35:18

much as he can because something

35:21

that people sometimes don't realize is

35:23

Dan. Harmon said not

35:25

only point nine for help

35:27

from the neck down and

35:30

reproductive health but also for

35:32

brain health said the same

35:34

exact hormones to.involved in fertility

35:36

and reproduction are also crucial.

35:39

For. The functioning of their minds. Just

35:41

something that we did not know. As

35:43

a community and killer Ninety Nine Days while

35:46

believe it or not to was discovered in

35:48

Nineteen Ninety Two. Iraq. Salary

35:50

University of I next to it the Us,

35:52

but it was only confirmed in Nineteen Ninety

35:55

Six. While engines insane. That's

35:57

crazy cat. Will end in under moon. A

35:59

pleasure. Prior and way earlier. Yes,

36:02

Yes, and you know about our own

36:05

brains. It is kinda shocking. And

36:08

is it's really important especially suddenly men

36:10

not to take anything away from an

36:13

article about what what happens is that

36:15

a brains are wired. To. Lead

36:17

a bit differently. Situated these

36:19

hormones word. Likely to told you that. I

36:23

guess. I'd say

36:25

my job The South Africa. Where

36:28

they waited. This hormones work is like

36:30

a key in a lock says no.

36:32

just the hormone. That's important is the

36:34

system And a system is comprised of

36:36

the hormones. What we caught: Sex hormones

36:38

which are not just for sex there

36:40

for a number of other things including

36:42

brain help in a receptor. To.

36:45

The hormone nice to latch onto

36:47

the sector ended the binding. The.

36:49

triggered. A number

36:51

of thing to need to happen

36:53

from energy production to immunity to

36:56

blood flow to neural plasticity is

36:58

really the receptor the triggers allergies,

37:00

other patients rights. So what's important

37:02

to know is that women's brains

37:04

and by women and in individuals

37:06

were born with a to x

37:09

chromosome and of female and quite

37:11

reproductive system. Always for

37:13

anyone has been with over his.

37:16

The. Brain is loaded with

37:18

estrogen receptors. Is the

37:20

package. Mother my sister. Yes,

37:22

for men or X Y

37:24

chromosome hold their it's when

37:27

a male reproductive system. the

37:29

brain responds presidentially to androgen.

37:32

Receptors. Didn't

37:34

mean status activators. Eschew

37:36

for women, Testosterone for men, Are.

37:40

Literally the shoe all. That

37:43

helps. Your. Brain run while

37:45

until you have a so that

37:47

these hormones and not just sex

37:49

hormones their brain activators. David.

37:52

Souter stain brain held.

37:55

And. Especially in some ways. cognitive

37:57

function, your sustain or. Why

38:00

they keep it up? Guess Now

38:02

What's important to realize is that

38:04

is not just the quantity and

38:06

quality of this for months to

38:08

change the difference between the genders,

38:10

but the longevity. So

38:12

foot women estrogen levels decline in

38:14

mid life in a relative relatively

38:16

short amount of time for some

38:18

women is very sudden it gives

38:20

you haven't and frac. To me

38:22

my surgical man opposed than to

38:25

change. it takes a couple of

38:27

months including menopause For women who

38:29

go to man opposes point hang

38:31

his sleep then it could take

38:33

years but skill we're looking at

38:35

and max of ten years. For

38:38

men the decline in testosterone nice

38:40

quite gradual usually which is not

38:42

underestimate any is just saying is

38:44

more gentle all their time. Many

38:46

men afraid I'm in the seventies

38:48

and eighties. May. Women

38:51

and it's very hard to find a

38:53

woman who still reproductively viable after eight

38:55

Fifty five. That that puts just can

38:58

put a strain on the brain chemistry.

39:00

Yeah, I got absolutely. So

39:03

many women. They I mean women

39:05

of testosterone as well and men have

39:08

estrogen as well. Similar system: women have

39:10

a predominance of estrogen receptors in

39:12

their brain, whereas men have a predominant

39:14

of androgens of yeah, so they're fundamentally

39:17

we have different brands. A.

39:19

Brains respond to dissident triggers when

39:21

one any in president, and estrogen

39:24

is important for men's health, and

39:26

testosterone is important for women's health.

39:28

But what research has shown? His

39:30

dad. Testosterone a

39:32

man and as to dial one

39:34

type of as jenny women seem

39:37

to be the master regulator slow

39:39

other brains. So does this specific.

39:43

Terminology. That as to

39:45

dial is the master regulator a

39:47

women's health. the with testosterone is

39:49

segments brand men's brains because it's

39:52

really base in the amount to

39:54

think that is hormones do and

39:56

evaluate bioavailability in dear he's got

39:58

a binding potential. Wishes

40:00

that when they attach to

40:03

the receptor binding is so

40:05

strong. And ah,

40:07

long lasting. The. Stick around

40:09

for the with a long time is

40:12

a very good said yeah that's and

40:14

then you you t says have a.

40:17

Number. One to get more activated power

40:19

but also to have a longer time

40:21

did it can release whatever chemicals to

40:23

have to produce. So

40:25

yeah, I think I'll hormones are important.

40:28

But. This seems to be. A

40:30

pig election if you will want hormonal

40:33

that matter, which makes sense Evolutionary standpoint

40:35

you had to pick it when I.

40:44

Saw. Suffering listeners? Yes. Send

40:47

is the kind of brains candid

40:49

I specialize in cement back and

40:51

is in neuroscience but also nuclear

40:53

medicine which is a branch of

40:55

radiology and does this kind of

40:57

brain scan is a position emission

40:59

tomography scanner set to eat. The

41:01

tracy were using here is one

41:03

of the most widely utilized is

41:05

glucose. Well you can. Attach

41:08

to a suit in Nineteen Thirteen

41:10

eighteen Compound says radioactive look I.

41:13

Guess we're looking a bit like the like.

41:15

a cross section of the brain from the

41:17

top? Yes. and it's sort of like. It's.

41:20

Like a heat map. It's just you

41:23

that be like a heat map so you

41:25

sustain. Read this is a

41:27

brain the looks like red to yellow

41:29

and green and then blew his dissolute

41:31

inside the brain which we need to

41:33

have food and said a brain is

41:35

a cushioning and nurturing hydrating means but

41:37

what we want to the Ted is

41:39

really did the silhouette of the brain

41:41

and is a very healthy look brain

41:44

to someone with forty three when she

41:46

started working with as you can see

41:48

that the top of the brain is

41:50

Sadie rent is on the state is

41:52

actually more bed in the bottom down

41:54

here which is perfect and then. If

41:56

I submit a ball ache which means is that

41:58

a symmetrical the left side is. Right

42:00

right? Name. Is kinda specular.

42:02

And is red metabolism. right?

42:05

Yes, Rand is means to give parts

42:07

of the brain have very high metabolic

42:09

activity. Thirty neurons are not only taking

42:11

up glucose very quickly, the earth, the

42:13

burning glucose to make energy and news

42:15

is great in his the you know

42:18

and say I actively a happy they

42:20

had a full of energy to have

42:22

a lot at work to do so.

42:24

I'm going to. Play.

42:26

This video. And.

42:28

So I told him we do follow

42:30

ups better follow people over time. So

42:33

does someone? got multiple brain scans with

42:35

iced over the years and we were

42:37

able to catch the transition. From.

42:40

Before Men opposed to after

42:42

well. That's

42:44

ten years in my life I. Guess

42:47

said. You see how is changing a

42:49

little bit. Going to loop around says

42:51

going to show it against the disease

42:53

after menopause a lot more green can

42:55

he was before rights it is is

42:57

before it Menopause bunch of red and

43:00

yellow and as this lady when two

43:02

men are pause the ranch in many

43:04

spas turned yellow. In the yellow turn

43:06

green. Yeah, you're basically saying

43:08

to soak up you know, if

43:10

you had like a dimmer switch.

43:12

Yeah, on brain energy metabolism. you're

43:14

seeing it like get progressively dimmer

43:16

overtime. Over ten years of it,

43:18

and forty four to thirty. Three

43:20

no less a nurse, she

43:22

learned to menopause faster, nested

43:24

insists teeth to one. While

43:26

yes, as they seven eighty

43:29

years. And. Demise into the

43:31

side by side is it to

43:33

see it in? What was seen

43:35

here is on average is a

43:38

thirty percent drop. In.

43:40

Brain energy levels. which means

43:42

a couple of things. Number.

43:44

One that manner pauses is

43:47

a neurological the active state,

43:49

right? I think most people.

43:51

Are aware that women goes from

43:54

an apologist and point to the

43:56

other fine we tend to associate

43:58

manager Paul it's with fertility. I

44:01

would think that men are poised to

44:03

send in that impacts the ovaries in

44:05

means that you're over is no longer

44:07

make follicles, the hormones and therefore it

44:10

at the end of your ability to

44:12

bear kids touching it. But what most

44:14

people don't realize specially women? Unfortunately, a

44:16

stunt men opposed changes your brain. As.

44:19

Surely as it changes your always perhaps

44:21

changes your brain more than your ovaries.

44:23

so does it does in neurologically active

44:25

process And I think it's important to

44:28

see the brain scan because they valley

44:30

day where women have been saying for

44:32

century right on it for you Go

44:34

to your doctor and you're saying you're

44:36

having some your you feel like your

44:39

brain is change if they are not

44:41

yourself you're having oldest difference in time

44:43

and your doctor it was say to

44:45

you it may be a threat. Than

44:49

a million. It's psychotherapy. And.

44:51

Here is antidepressants. Just come back in

44:53

five years so we need we need

44:55

to have this to guy it and

44:58

inform conversation know just for the patients

45:00

before the doctors as does is actually

45:02

happening. This

45:05

is Not just your brain is

45:07

changing. There. Are consequences

45:09

to your brain changes

45:12

his way and some

45:14

are. Sentence. In

45:16

a does ups and downs to man

45:18

apostle Pros and cons which is driving

45:20

the book Modern that but in terms

45:22

of the race and a con know

45:25

there are you on these these changes

45:27

this was the first today we did

45:29

with done many. Since. Any.

45:31

Chances that men are poised has

45:34

an impact on the brains. Teacher.

45:37

Cincinnati. Energy. Levels:

45:39

Biochemistry and Connectivity.

45:43

And we've been using other Marcus to

45:45

find out even more. But if the

45:47

the really seems to be a quite

45:49

a bit of a change in does

45:51

remodeling. Can.

45:54

Come we'd seen him

45:56

and medical risks. The

45:58

symptoms are things. Hot

46:00

flashes, A threat Just.

46:04

And sleep disturbances, insomnia but

46:06

also depresses sentence and and

46:08

die a D M Most

46:10

concerning for some women at

46:13

least if the forgetfulness, the

46:15

brain fog and a memory

46:17

lapses and exhaustion. The

46:19

city to him in clinical. Is cause

46:21

mental fatigue but people say brain fog.

46:24

Those. Are very real. Symptoms are menopause

46:27

to have nothing to do with

46:29

your ovaries and everything to do

46:31

with your brain doesn't Neurological symptoms

46:33

that come from the ways that

46:35

man opposed changes your brain. That's

46:37

important to realize that because treatments

46:39

are available solutions that available then

46:41

many different things that can choose

46:43

from but we need to choose

46:45

not assume we may have no

46:47

problems. This is an average images

46:49

one person bout. We have hundreds

46:51

of people now and is kind

46:53

of other edge. For some

46:55

women is a breeze. You know

46:57

one day they're down with their periods

46:59

and at said that day I the

47:01

exception. Is a

47:03

big rage range of symptoms

47:06

to go from the occasional

47:08

hat/and forgetfulness to women been

47:11

suicidal were. And is

47:13

strange, is not recognized and does

47:15

not formalized. in Madison. It drives

47:17

me whether they are for wall

47:20

to. We have

47:22

this definition for pregnancy.

47:25

For. Instance Ray it took forever and

47:27

to the nineteen nineties, But in

47:29

Ninety Nine two four post partum

47:31

depression was finally legitimized and is

47:34

now part the medical textbooks. and

47:36

we understand that there's a range

47:38

sent women a perfectly fine and

47:40

we met her baby blues in

47:42

our daily lives said have had

47:45

depressive symptoms. Occasionally some women have

47:47

legit depression and women a suicidal.

47:50

They can have postpartum psychosis so now

47:52

the we know we have little popularity

47:54

and. They give validity.

47:57

To. The sushi even Pms. You know, many

47:59

women. Pms and is not.

48:02

Part. Of any medical

48:04

diagnostic textbook, It's

48:06

not a medical entity is no matter.

48:09

No. Matter how how many women have it, it's

48:11

now this. Is

48:14

wild. It's weird though. women are

48:16

mean, historically an underappreciated sex drive

48:19

and of medicine them is that

48:21

in mind lives in. Yeah, I

48:23

mean we've had a lot of

48:25

conversations about yeah, women's sexuality and

48:28

hormone health like does it's it's

48:30

a it's a big problem, but

48:32

you know I'm image. but we're

48:34

We're writing those rocks here on

48:37

the Genius life. Actually two thirds

48:39

of our audience or female adults

48:41

lenders. I. Love.

48:43

It. Here and you know what another thing

48:45

I want to sustain. Menopause.

48:48

Does not happen when you old. Paint.

48:51

We we are led to believe that men

48:53

opposes tend to have to see you when

48:55

you're old and is is not true. When.

48:58

Sunday women were fully menopausal in

49:00

their twenties. The director that he

49:03

can have this good Pr eyes

49:05

Tammany have any sufficiency? Well yes,

49:07

they are women who go through

49:09

Menopause contains in their thirties. African

49:12

American women tend to go to

49:14

man applies earlier. Than

49:16

women have other ethnicities said

49:18

example which. Can. Find information

49:20

on anywhere? Well yes and then

49:23

they don't. Women who go from

49:25

Enterprise is called. Earlier p

49:27

Mature men a python is before

49:29

age forty five and you can

49:32

happen because a genetic could be

49:34

ocean conditions and unfortunately very often

49:36

his medical treatments he know like

49:39

will threat to nice. Is

49:41

the number one cause when the always

49:44

has been removed surgically they could it

49:46

causes. Surgical. Menopause at any

49:48

age He says before Menopause always

49:50

in. The dose of treatment

49:53

for cancer and so many women who

49:55

develop an applause. And. Then or

49:57

via because the cancer treatments.

50:00

Radio is permanent and with

50:02

to not. Formalized.

50:04

That in Madison, there's

50:06

no framework. To

50:09

intervene. I.

50:11

Did and to me should it a

50:13

cancer doesn't come back days of is

50:15

it It's of famer for that that

50:17

is So leaders support Been also to

50:19

women who are going through that. Is

50:23

wild. Yes, aren't to say to

50:25

women who are listening to this. You

50:27

want to if you can issue not

50:29

in mine opposed. Yeah, you want to

50:31

prepare. Because. It does not

50:34

happen when you're old. It happens in

50:36

your late forties early fifties, which is

50:38

not owed by any definition. And for

50:40

those two I passed Menopause out, There

50:42

are many things that one can do

50:45

to really support brain health. At.

50:47

That stage in life as well.

50:49

Because the truth is that the

50:51

vast majority of women spend over

50:53

forty percent. A. Day lived in

50:55

the post Menopausal stage and crazy,

50:57

yes. A to long time and a long

50:59

time. Yeah, so I guess the i mean all

51:02

of you will probably listen to Was wondering about

51:04

Hrt Yes Ah and the Se. Ha!

51:07

Ha is controversial as you

51:09

know many people associate that

51:11

with breast cancer. To marry

51:13

we can talk about. His. Yeah,

51:15

I can really should be controversial. I

51:18

can't tell you how many my friends

51:20

right? Or on Trt. Is.

51:24

My friends are in their thirties

51:26

their forties. That and there's some

51:28

are even open about it. They're

51:30

onto your teeth and this mm

51:32

and even open. So why are

51:34

women so ashamed? Or. He has

51:36

never been associated with an increased risk of

51:38

cancer. A only

51:40

when a shame. Heart disease though perhaps?

51:42

no, I don't actually know the and or

51:44

but. Then and think it's

51:47

been popularized as the bet

51:49

link. So issue is t

51:51

guide a really bad reputation

51:53

or in two thousand and

51:55

two window Women's Health Initiative

51:57

collapsed the Women's Health Initiative.

52:00

Sadly to date the

52:02

largest clinical trial a

52:04

women's health that was

52:06

looking at using Horman

52:08

take Estrogen and progesterone

52:10

for prevention of things

52:12

like heart disease and

52:14

osteoporosis and dementia and

52:17

and. It. Showed

52:19

exactly the opposite. That.

52:21

The risk of all these conditions

52:23

was increased. By. Taking hormones

52:25

and. Many years

52:27

later, it everybody hates a study.

52:30

Even. If you will will punish the

52:32

in because they got so much hit

52:35

for s because really the media overemphasize

52:37

the connection. With cancer. And

52:39

a lot of people. As soon as you mentioned

52:41

hormones are like no I don't I don't want

52:43

to get breast cancer, have rather had to have

52:46

fresh as the osteoporosis the night flight center into

52:48

depression, anxiety rather. See

52:50

a terrible but I'm not going to this cancer.

52:52

It can take revenge. Is. Horrible. but

52:54

we'll send it to put do is

52:57

to cancer in context. That.

52:59

You real contest that is I said to

53:01

you. Let's say they you

53:03

are. You have very high cholesterol. It was

53:05

a pleasure to woman and you go to

53:08

the doctor and you have a family history

53:10

of heart disease. And

53:12

you don't' you? You have a high cholesterol

53:14

and the doctor says how about a starting.

53:19

With. You what I take anything about to

53:21

start know them very high risk. When.

53:23

You consider taken Starting with you ask me what?

53:25

My risk of breast cancer with a stunning. I

53:27

would have do all the other lifestyle stir fry. An

53:30

hour but I'd say we are you ask me?

53:32

Well was married to breast cancer with the starting.

53:36

with a sub zero. Yeah

53:38

higher than with his heard it. Dot.

53:41

Is it higher and higher? With eight hours

53:44

he did it Now. And a risk of breast

53:46

cancer is higher is you take a stand in. There.

53:48

Is with eight Or to? yes? Sir, I'm telling

53:50

you, context is in for an end.

53:53

Why? Risk of breast cancer is higher

53:55

issue During two glasses of wine today.

53:58

What? The hell yes it's either. Hi

54:00

your issued a flight attendant. To.

54:02

Their Life. I'm serious misinformation out there

54:05

are. Than the rest is not to say

54:07

they do is no increase in risk. By

54:09

the nice to be contextualize vr, what

54:11

kind of increase are we talking about?

54:14

Rosy Light two cases out of the

54:16

have a added ten thousand with them.

54:18

for me. in a sense, after thirty

54:21

cases outta ten thousand and are retiring,

54:23

still is a. Yeah, you know

54:25

and I'm sure over time we're getting

54:27

better at understanding who is actually gonna

54:29

see the risk increases. I know and

54:32

I'm sure many women won't see want

54:34

their actually have there is increased at

54:36

all. Yes, it depends on the

54:38

simulation and for how long you take

54:40

it they can say is you under

54:42

within Talk about it. But the point

54:44

is it really needs to be an

54:46

individualized conversation with your doctor. The takes

54:48

into account your own individual risk. For.

54:51

Breast Cancer India and. Also

54:53

provide accurate information a what kind

54:55

of these are talking about The

54:57

disappointment by because if you said

54:59

is and is a professional societies

55:01

called in North America Menopause Society

55:04

that looks at all the available

55:06

evidence. Independent guy then saw the

55:08

time. I. Mean had hundred and

55:10

and hopefully did they might off

55:12

and a lab date. The guidance,

55:14

mouth and bad day I the

55:17

ultimate authority than any Twenty Twenty

55:19

two. They published revised guidelines that

55:21

stayed there for women who are

55:23

eligible. To. Take our men who

55:25

are within ten years. Or. The

55:27

sign on menstrual period Usually

55:30

age sixty sixty five Taking

55:32

Horman. Has benefits,

55:36

And. Is safe. For.

55:38

Most women you take him for a certain

55:40

amount of time. We should take about five

55:42

years to get you through the transition. Oh

55:45

gotta pay via. The risk of breast

55:47

cancer is actually not increased Issue: Do

55:49

that. With. Some. Specific

55:51

formulation for specific amount.

55:54

Of like how many women will will.

55:57

Not take the a turkey for fear of

55:59

risk. Cancer but I'm a rink. Alcohol throughout

56:01

the entire period. I didn't know. Didn't.

56:04

Know. Because. He. Turkey

56:07

has been popularized in the cancer

56:09

and using poison in wine have

56:11

not been. So what does the

56:13

data's show with her birthday party in Britain

56:16

brief him? Brain? How at so. Either

56:19

know you you hear about this headlines

56:21

that every couple the month is a

56:23

new study the comes out. This shows

56:25

that either H T prevents the man

56:27

shot or a charity gives you so

56:29

much Never yes it's really funny it's

56:32

that is us and are funny of

56:34

in a is you are considering taking

56:36

hormones if your own harm as ended

56:38

the one started they cannot just recently.

56:41

That. Ended up. Everywhere

56:44

on Tv in newspapers. New York Times

56:46

he was due to maybe ninety was

56:49

to join and been there was in

56:51

England and he was showing an increased

56:53

risk of the men sat with hormones

56:56

and then I lost and married his.

56:58

Patients. Don't aren't gonna hate

57:00

every that. He was a what

57:02

and sorry set fine. You

57:05

cannot look at a single

57:07

study. And. Not

57:09

the context, but that's not the only

57:11

studied this looked at days to the

57:14

others. Safety: Sixty One Hundred studies the

57:16

oath to provide information. So what we

57:18

need to do it was it's not

57:21

really my thing, they usually do brains.

57:23

Then this case I said to my

57:25

statistics intimating we're going to pivot. Were

57:28

going to answer these questions that were

57:30

going to the mega analysis and multilevel

57:32

regression of all available data so far

57:34

and we're going to get a clear

57:37

picture the state, the numbers now. Do

57:39

opinions. Said Jesus.

57:41

The largest med analysis so far. so

57:43

good. Yeah, this kind of a I

57:46

had never done one summit of voters

57:48

said I felt compelled. half the presses

57:50

to like twenty only three amazes me. I.

57:52

Do you see was a Wicked Lucky

57:54

who isn't? Cnn? New York Times listed

57:56

Jonah because it's important. That is what

57:59

women want to. Amen. And

58:01

server, it's guy. I believe this. more

58:03

than six million women. In dust

58:05

in the Med analysis from all over

58:07

the world While his different formulations the

58:09

what we found is that to thinks.

58:12

The type of formulation mandarin

58:14

and when you take it.

58:17

Matters. If you take you for men

58:19

upon as you're going through it or if

58:21

you take it a lot after. Men:

58:24

A point that. Has a difference now for

58:26

each had to that know how much you want to know

58:28

by does I think it's important to note because a lot

58:30

of women don't know that. The

58:33

kind of hormones you take depends on whether

58:35

or not you have a uterus. That.

58:37

A many women. As the

58:40

you that is removed for a number of

58:42

reasons medical reasons if you have to you

58:44

that are you need to take it projects

58:46

that. Guy with estrogen

58:48

yesterday at another Us. Always estrogen

58:50

by Danny. You add a progesterone on

58:53

top. Got it? You don't has a

58:55

uterus? estrogen only. Go. Get A

58:57

with a uterus, estrogen, and progesterone

58:59

without a uterus as originally. Now

59:03

I'm sure that all the relevant her. Three.

59:05

Of my listeners. Who have no. I

59:07

think it's gonna be relevant. All of them really

59:09

is. A Love it. Yes, It's important

59:12

in a lot. I'm seriously. I know

59:14

that. Five am know but this is super

59:16

exciting as really great Get to begin. With. From

59:18

her many women can't get a hysterectomy in the

59:20

United States and. It's common. I've no idea

59:22

when. And eight. One in eight. Yes. Is

59:24

the second most common surgery After effects.

59:27

Whoa. What's the most common reason that women

59:29

would get the? Cancer and

59:31

Indonesia's. Interesting well

59:33

as doesn't know my wheelhouse

59:36

so this fan. I one

59:38

in three on a member like

59:40

a hundred percent. Well yes yes

59:42

so it important information estrogen on

59:45

the issue. take him before. He.

59:47

Of Finance Minister Pierre, The within

59:49

ten years off does a thirty

59:51

two percent. Reduction. In

59:54

the risk of Alzheimer's Disease later

59:56

on in life, statistically significant reduction

59:58

is a slew women who. The

1:00:00

hysterectomy, surgical menopause, different manner parts

1:00:02

that it's really does. This is

1:00:05

a good result goes away since

1:00:07

East into Foster is thirty two

1:00:09

percent produce fiscal Alzheimer's disease late

1:00:12

in life. When you take estrogen,

1:00:14

When you take estrogen for maniples right

1:00:16

after thirty, Format has right after surgery.

1:00:18

Yes, got it. If you. If you

1:00:20

take it more than ten years. After

1:00:23

the surgery then has nice

1:00:25

hat. Got it on us. Amethyst got

1:00:27

and this is for women that have had a

1:00:29

historical fact that. Everybody

1:00:32

S. Now his threat like

1:00:34

gonna have a oh that's right and

1:00:37

you take estrogen progesterone for man a

1:00:39

point. Or within ten years,

1:00:41

twenty three percent. Reduced. Risk

1:00:43

of alzheimer's disease. To get years

1:00:45

ago think there are twenty percent you're hunting

1:00:47

as they can get me a pill is

1:00:49

slanted Maurice twenty percent. Events that easy

1:00:52

to take him word and ten

1:00:54

years after define a mess with

1:00:56

p N device can increase know.

1:00:59

The peak. Increases. Because of

1:01:01

that one study, the Women's Health Initiative,

1:01:04

which is the largest, suffices. Driving

1:01:06

yes I said the our. At

1:01:08

the between him. And is a big

1:01:10

outlier because the other studies so

1:01:12

more variable ss and some studies

1:01:15

actually protect his said. This whole

1:01:17

saying is not significant does not

1:01:19

reach the threshold for statistical significance,

1:01:21

which means there's a lot of

1:01:24

the ability and we're not looking

1:01:26

into what is driving the as

1:01:28

sacked in. It looks like it's

1:01:31

a specific type of progress to

1:01:33

gin which is a synthetic type

1:01:35

of progesterone name was used in

1:01:37

the past and. We don't really

1:01:39

use the chronically unemployed Right now is

1:01:42

my by identical wow moments. So by

1:01:44

a tentacle four months appear to be

1:01:46

safer. Full. They're on. And

1:01:49

it kinda does is very promising. To

1:01:51

risk reduction in mid life. So

1:01:53

I mean for somebody who.

1:01:56

Is. Having a hysterectomy? There's a lot.

1:01:58

You can do something. Production. Yes

1:02:00

and I will say this deck

1:02:03

Professional Societies. The. Have it in

1:02:05

the guidelines for women who have their

1:02:07

especially. Hysterectomy. With the

1:02:09

ovaries embalmed such as an infrared

1:02:11

to me. as well

1:02:14

then considering hormonal treatment

1:02:16

is actually have recommended

1:02:18

and current guidelines suggest

1:02:20

they you was for

1:02:22

women who are eligible.

1:02:25

He was tight treatment right after

1:02:27

surgery and continue taking hormones and

1:02:30

peel The average age of man.

1:02:32

A Polish wishes safety. Is

1:02:35

is in professional guidelines know obviously of the

1:02:37

woman is different why do you have you

1:02:40

already taken out? Why they have your uterus

1:02:42

check out so it's case by case. right?

1:02:45

But as long as there are

1:02:47

no contraindications than one. Mana therapy

1:02:49

can reduce the risk of cardiovascular

1:02:51

disease, can reduce the risk like

1:02:53

a parody, can reduce the risk

1:02:56

of depression and anxiety, and potentially

1:02:58

protect against cognitive decline. Well distant

1:03:00

and to consider to do this

1:03:02

reach does this risk reduction with

1:03:04

women who have their uterus You

1:03:06

to write for the plural uterus

1:03:08

is to the when does one

1:03:10

know I know that from make

1:03:12

for many women women The women

1:03:14

who have their uterus is yes

1:03:16

it is. It's ah I'm. Taking

1:03:20

estrogen and progesterone did this

1:03:22

reach statistical significance? I was

1:03:24

a trend. He was Zero And Zero

1:03:26

Seven. Gotta we gotta close. To

1:03:28

been not quite. Again, it depends

1:03:30

on the type of. Suggested

1:03:33

to God has done rejected any

1:03:35

they get produced a jannik formulation.

1:03:37

So with regard to Hrt, we still

1:03:40

need more evidence. Or. Yeah, I mean

1:03:42

it's so much for nine years.

1:03:44

isn't my biggest take a message

1:03:46

from the studies that there is

1:03:48

still much variability ended. it has

1:03:50

nothing when genius And also I

1:03:53

think this would make sense to

1:03:55

his distinctively bites. To me clinical

1:03:57

trials that look at taking hormones

1:03:59

now. Live In The

1:04:01

End Point. Is. A decline

1:04:03

to demand. So twenty years later, Don't

1:04:06

seem to be the best

1:04:08

strategy. right? So.

1:04:11

That's Not going to happen. What

1:04:13

we need to do there hasn't really been

1:04:15

done is that we need to look a

1:04:17

whore months now and meet life menopause and

1:04:19

then your brain scans. And.

1:04:22

Other markers of a time his

1:04:24

fist and see the treatment can.

1:04:26

You. Know either prevent the markers for

1:04:28

showing signs of Alzheimer's and keep them

1:04:31

stable or even reduce the risk And

1:04:33

in that would be the ultimate proof

1:04:35

that is it. Just for now is

1:04:37

so research. Except

1:04:40

the benefits that are professionally sound

1:04:42

like the indication for Hrt for

1:04:44

women with hysterectomy. but I didn't

1:04:46

that his research but I think

1:04:48

it's it's encouraging. And

1:04:50

for women. In pre

1:04:53

Menopause and Menopause would say the same. Outside

1:04:56

of their that conversation surrounding hormones,

1:04:58

the same rules apply with regard

1:05:00

to exercise an entire sleep. Yes,

1:05:02

Yes, it's so the symptoms

1:05:04

and man applies, tend to

1:05:07

hit hardest. Before man a

1:05:09

point that I know so confusing

1:05:11

to so many women because we

1:05:13

talk about men are point as

1:05:15

a day did arrive at a

1:05:17

date on the calendar. it is

1:05:19

not two men opposes the process.

1:05:22

It can take years and no

1:05:24

longer having a period is actually

1:05:26

the outcome. On to

1:05:28

process the end God or the process

1:05:30

The problem is before. And.

1:05:32

Is called Perry. Rise Only it's

1:05:35

only diagnosed after you've turned mine.

1:05:37

Did it without. Yeah, Yeah, it's.

1:05:39

It's it's. probably the only situation

1:05:41

in Madison for you. Diagnose Sundance

1:05:43

retractable a year by saying I'm

1:05:45

a man City be without. Appear

1:05:47

at eleven Am I at. It's

1:05:49

twelve is twelve months. Two months are funnier

1:05:52

without it. Was one hour period. You're.

1:05:55

In none of my men officially that

1:05:57

yeah it's a transition can take anything

1:05:59

from it. You go to his

1:06:01

spontaneously. It can take anything between

1:06:03

two years and fourteen, and fifteen

1:06:05

may not be. A breeze.

1:06:08

And. I could be hard to think. it's

1:06:10

important to recognize the their think them. That

1:06:12

can be managed. Some. Requirement

1:06:15

for those were interested in harm as many

1:06:17

people are not. And. So

1:06:19

in that case is lifestyle

1:06:21

and exercise can really help,

1:06:24

especially cardiovascular. Aerobic exercise has

1:06:26

a good effect on promoting

1:06:29

elation. And as the

1:06:31

brain fog and commission but then strength

1:06:33

training since to be very helpful for

1:06:35

mood. As. Well as muscle

1:06:38

mass, metabolic activity and then

1:06:40

there's flexibility imbalance, exercise it

1:06:42

it also good for strife

1:06:44

and sleep. So it's

1:06:46

a combination of things that can be

1:06:48

helpful. Think it's worth looking into? Diet

1:06:51

can help. Is increasing

1:06:53

evidence that processed foods it is

1:06:55

also really bad for men are

1:06:57

point yeah you get through. You

1:06:59

may get through menopause earlier. Issue.

1:07:03

Consume a lot of processed foods

1:07:05

as compared to. I

1:07:07

realize you know you could have brought it

1:07:09

upon you and early onset the man or

1:07:11

point was nobody needs really. Know

1:07:14

and I and I think it's also

1:07:16

the overconsumption of these ultra processed foods

1:07:18

that are that are bringing that uplink

1:07:20

Puberty, Upright and Co and then. Probably.

1:07:23

Playing around precocious puberty. Yes,

1:07:26

yes, And endometriosis a new fertility

1:07:28

and on this kind of endocrine

1:07:30

disruptor it does seem to really

1:07:32

have their. While to on

1:07:35

the on you say you've written

1:07:37

on your Instagram what we eat

1:07:39

now in our twenties, thirties and

1:07:41

beyond could help prevent dimension decades

1:07:44

later. So any favorite brain foods

1:07:46

of the moment give us your

1:07:48

top three favorite brain foods of

1:07:51

right now. He.

1:07:53

To they get. Gently

1:07:55

foods or nutrients. And.

1:07:59

Blackberry, He. Really good.

1:08:01

Three to five an antioxidant. Gonna

1:08:05

go home, sweet potato because now you eat

1:08:07

them. A lawsuit is actually to figure out

1:08:09

what have you ever? I'm. The only

1:08:11

serves to like olive

1:08:13

oil producing oil, flaxseed

1:08:16

oil. Flaxseed Oil. Yes

1:08:18

has even more Omega Threes,

1:08:20

ten olive oil. Doesn't

1:08:22

taste as good. Night. By.

1:08:24

The really good cell line and

1:08:26

get fat. Anybody want said I

1:08:28

need it? And yeah, And

1:08:31

I'm not as flaxseed oil keto you

1:08:33

are my cat. or because it's it's

1:08:35

alpha linoleic acid which is on your

1:08:37

body has converted to it's usable form

1:08:39

in the body. Which and you know

1:08:41

people typically are very good at doing

1:08:43

so. I'd rather I'd rather know what

1:08:45

it isn't getting. Any fish

1:08:48

oil would be my go to choice. You

1:08:50

know you're a high quality however sell it

1:08:52

to you know not already out. Some end

1:08:54

I'm going to say oh and as a

1:08:56

food yeah I or fish like out as

1:08:58

a fish than six can drink classes like

1:09:01

oil You think. I.

1:09:03

Would humbly. The Ginkgo, an Xj, some

1:09:05

Obama, I will they were Now I'm

1:09:07

Italian and even then yeah I have

1:09:09

that know I'm going to eat the

1:09:12

fish yes and for as an oil

1:09:14

on probably going to use. Extra

1:09:16

Virgin Olive was yeah, you know, Class

1:09:18

because also the other thing about these

1:09:21

like. About flaxseed oil

1:09:23

in in particular. Is.

1:09:25

That omega threes are

1:09:27

actually more prone to

1:09:29

oxidation then omega Six

1:09:31

Fat. They. Have us and

1:09:33

forgetting now with the another double bonds and

1:09:36

like. Hashtag

1:09:38

chemistry there's something sisters there is. there

1:09:40

are more double bonds in our the

1:09:42

Omega three fatty acid and so if

1:09:44

you don't know how the flaxseed oil

1:09:46

which is very high in omega three

1:09:48

fats plant based make a three fats

1:09:50

pro make a three Fats. Nonetheless if

1:09:52

you don't know how that bottles been

1:09:54

stored prior to it any other your

1:09:56

kitchen it could have been sitting in

1:09:58

a truck in seat. You did have no

1:10:01

idea in oil they're very damage brown. Net

1:10:03

is true, I got mine in

1:10:05

glass bottles. And Hartford.

1:10:08

Say. Try and is a know it they're

1:10:10

doing that Who? No no you're right now

1:10:12

for know it. Iran's said. You.

1:10:14

Don't Hour drama. Know you don't one

1:10:16

that for the snow lane my ankle

1:10:18

have a nice Italian little else. As

1:10:21

a bunch of olive trees

1:10:23

and he makes olive oil.

1:10:27

It tastes so different than anything I

1:10:29

can get here. quo. It's

1:10:33

surely it's be either. Almas.

1:10:35

Pepe the Aftertaste.

1:10:38

Are. You can tell that is active. As.

1:10:40

You can. Get away you

1:10:42

can see all that did some food

1:10:45

is having an effect since. Then.

1:10:49

I saw away with with x with them

1:10:51

to the area. Next original will for sure

1:10:53

it one. And

1:10:55

it's kind of any are like your your

1:10:57

ancestral diet or down cuisine is like rich

1:10:59

and extra virgin. olive is an air as.

1:11:02

An alien in China and other kind of oil. until

1:11:04

I got. here in New York any

1:11:07

got all these like fake like

1:11:09

autre process I. Don't die than that.

1:11:11

Yes to everywhere. Everywhere. Now.

1:11:13

Soybean Oil? yeah, know any. Heard about

1:11:16

it until I moved. There

1:11:18

is no hits That was a

1:11:20

weird things about about. The.

1:11:23

The continual promotion of these fat

1:11:25

is. Helpful, fat

1:11:27

and eleven years I like. Who.

1:11:30

You don't even have to make any health claims around, and

1:11:32

they're not. They're not part of the traditional Mediterranean dietary pattern.

1:11:36

Like. That right there says something.

1:11:38

right end. Of the coconut

1:11:40

I am. Trickle. Hubble's.

1:11:43

Great. And it's from Thailand writer more

1:11:45

ever their offices a kind. Man

1:11:48

or this was so fun I shouldn't have heard.

1:11:51

A lot of ground has anyone my thing? absolute.

1:11:53

Laugh along with absolutely of the I went

1:11:55

to San in it's a new the fish

1:11:57

in it said it's an Ama cod. About

1:12:00

men opposed, it really looks a little

1:12:02

bit more to positive While ago. Through

1:12:04

it to get can. Sit. On

1:12:07

a guy on here. so. I.

1:12:10

Think as as humans we know it it

1:12:12

women as some point will go through menopause

1:12:14

and as the end of it right? But

1:12:16

in reality. It's. A scientist men opposes

1:12:18

a little bit of a riddle. Because.

1:12:21

It doesn't happen very often in

1:12:23

nature, it that seamounts to go

1:12:25

through menopause and live. Talk.

1:12:28

About it is only for

1:12:30

animal species. The good man,

1:12:32

I'm point and out Leave

1:12:34

it. Yes, there is Wales.

1:12:37

Well yes. killer Whales normal.

1:12:39

Another. Kind away I can't remember

1:12:42

the name of some and some

1:12:44

ellison. Isn't Ellison

1:12:46

one type of July? And

1:12:49

a bug. The. Japanese A

1:12:51

is it acid? That here a

1:12:53

fit and women. So. Do

1:12:56

something special about humor men opposed

1:12:58

to a theme desert consideration and

1:13:00

there's a lot of with evolutionary

1:13:02

theories and explaining why make sense

1:13:05

for women to remain alive. But

1:13:08

not be reproductive ever. And I

1:13:10

think it's just obvious way that

1:13:12

the older you are the chances.

1:13:15

You. Have would die in childbirth

1:13:17

and then talking ancestry friend.

1:13:19

Modern medicine wasn't quite there,

1:13:22

so I make more sense

1:13:24

for women to remain productive.

1:13:26

Without. Being reproductive said it. Then

1:13:28

you can help your own daughters

1:13:30

and sons to have my kids.

1:13:33

Are you still passing on your

1:13:35

genes to the next generations? Know

1:13:37

what does that mean For my

1:13:39

brain perspective? Is

1:13:41

it posted Guy: According to

1:13:43

Darwin an evolutionary theories but

1:13:45

in reality a dissenting neurological

1:13:47

the happens to your brain.

1:13:49

Did I find fascinating? Get

1:13:51

keep a very short by

1:13:53

Men and women go through

1:13:55

neuroendocrine transitions in nice. To.

1:13:58

Started puberty and. The

1:14:00

end with men opposed and women and and your post

1:14:02

from and. They their own. For

1:14:04

women we have three peas. Puberty.

1:14:07

Pregnancy every time you're pregnant

1:14:09

and paramount importance and that

1:14:11

is fascinating to think that

1:14:13

that this is basically the

1:14:16

system. That. Connects the brain

1:14:18

to the all that is. That

1:14:20

were born with bet is

1:14:22

only activated during puberty. And.

1:14:25

Then is reactivate it every time

1:14:27

you get pregnant and then is

1:14:29

deactivated with man a point Where

1:14:31

does that mean immense the during

1:14:33

puberty. The connection turns

1:14:36

on a your brain starts

1:14:38

changing. Does. It rewiring and

1:14:40

remodeling that takes place where Asa

1:14:42

for men. As the boys and

1:14:45

girls had this weird the brain

1:14:47

just sheds the tone of neurons.

1:14:49

we lose brains out in the

1:14:51

brain shrieks so. That

1:14:53

a friend a brief perspective is

1:14:56

smart. Kid. Is very expensive

1:14:58

to keep all these neurons and synapses if

1:15:00

you don't need them is best. agree that

1:15:02

up. So the brain is getting lena and

1:15:04

meaner. If. You will Yes,

1:15:06

And that allows you to.

1:15:09

Go. On autopilot for certain

1:15:11

things. right? Like you can

1:15:14

ride your bike you don't need

1:15:16

notice the map each step providing

1:15:18

a bike or you can tie

1:15:20

up your shoelaces hopefully him brush

1:15:22

your teeth. The August connections can

1:15:24

go right at the same kind

1:15:26

of brain. Reminders itself said if

1:15:28

regions that are important for cod

1:15:30

or mind a mentalizing. Get.

1:15:32

Better connected to each other and

1:15:35

do work better together. In

1:15:37

these are the key ones

1:15:39

are hippocampus and amygdala. You

1:15:41

motion sensor them into prefrontal

1:15:43

cortex, thinking and reasoning. an

1:15:45

impulse control. So as you

1:15:47

go to puberty, the frontal

1:15:49

cortex is not yet developed.

1:15:52

See. A Primitive regions. Can.

1:15:55

Take charge and I take the

1:15:57

lead and that is correlated with Raxit.

1:15:59

Reckless. During adolescence and all

1:16:01

these. Hearing more?

1:16:03

About without a drama. Exactly

1:16:05

where did the same time those

1:16:08

changes are enabling your brain to

1:16:10

become much who are. You

1:16:13

developing social cognition your you become

1:16:15

able to understand without if people

1:16:17

feel and think. And

1:16:19

you can find ways to strategize and

1:16:22

deduct say become a member of the

1:16:24

size of death the purpose of the

1:16:26

team brain. You know, ugly?

1:16:28

She is. A

1:16:31

great time. Yes, business

1:16:33

to depressive symptoms and we're not. Grow.

1:16:36

By. You're growing puberty. Same.

1:16:39

Exact thing the brain thinks every

1:16:41

time you're pregnant. Well, yeah, Industry.

1:16:44

Me parts give reactivated even though

1:16:46

you're a frontal cortex is the

1:16:48

and headline better get reactivated because

1:16:50

you have to protect that kit

1:16:52

And they're cute, can speak. So.

1:16:55

It's you primitive brain. the new

1:16:57

you upgrade the cod a mind

1:16:59

to document allies video infant. And

1:17:02

understand what you. Need slowly moving

1:17:04

forward. Mommy brain dead demanding bring

1:17:06

us money raised their power. Is

1:17:09

that you're so focused on huge hit

1:17:11

the you become almost like a superhero

1:17:13

A you you can do incredible things

1:17:16

as a mother. fresh and funny but

1:17:18

from Vermont is an actual neurological. The

1:17:20

arrangement they did the same time gives

1:17:22

you the baby blues are did post

1:17:25

partum depression in the brain fog and

1:17:27

now the things that can happen to

1:17:29

him. Pregnancy. Fast

1:17:32

forward to man a point is

1:17:34

the same ceased and it gets

1:17:36

deactivated. So. All the connections

1:17:38

that would needed. To. Get

1:17:40

pregnant and then ticket at that

1:17:42

kid can go. To.

1:17:44

The brain his friend insurance again is

1:17:46

my interpretation a you may get the

1:17:49

sentence and the same time the where

1:17:51

does the upgrade. The. Upgrade

1:17:53

is Dead Man Opposed seem

1:17:56

to be enroll logically predisposing

1:17:58

women to the. Phase

1:18:00

of your life when you're

1:18:02

going to be taken care

1:18:04

of others. And for women

1:18:06

who postmenopausal have measurably grader

1:18:08

empathy. Didn't. Any added

1:18:10

individual of any age to

1:18:13

say find yourself up and

1:18:15

those said is something called

1:18:17

emotional Mastery or emotional Control

1:18:19

video mean tele is selectively

1:18:22

trent off to worth negative

1:18:24

things. What Are

1:18:26

you still responding happily emotionally

1:18:29

to positive things to happen

1:18:31

to good things to happen

1:18:33

to you, but your ability

1:18:35

to ignore. Upset and

1:18:37

stuff is actually increase Increase To

1:18:40

say you had this emotional my

1:18:42

student. Many women report after menopause

1:18:44

they call it given fewer. As

1:18:47

now you have. By

1:18:49

neurologic Philly is is kind emotional

1:18:52

regulation to blow. guess that is

1:18:54

app regulated. pretty think she's got

1:18:56

some our Then it gets you

1:18:58

the nice endorse the happiness or

1:19:01

contentment we say. I really want

1:19:03

to say is not all gloom

1:19:05

and doom that there's usually a

1:19:07

rebound in life, contentment and happiness

1:19:09

after menopause, to the point that

1:19:12

a lot of women who are

1:19:14

postmenopausal report didn't report been significantly

1:19:16

happier. Debate. Himself were

1:19:19

before. Men: Upon. Impart,

1:19:22

Maybe because it does neurological com.

1:19:26

The. And a non does. It is a new

1:19:28

research and we need more like that. Was

1:19:30

sure that I thought it was so fascinating.

1:19:32

It is. Yeah, It's.

1:19:35

Super. Empowering and. And

1:19:39

dumb. That is a

1:19:41

wonderful way to think about this thing

1:19:43

that tends to be shrouded with think

1:19:45

stigma, stigma, doom and gloom. Yes,

1:19:47

ages and sexism. Am also

1:19:50

yeah. And distance. Man.

1:19:53

Working people were. Where

1:19:56

can people pick up your book? And who's who

1:19:58

directs before the Menopause brain. Really,

1:20:01

I think of it as a love letter to

1:20:03

woman head. I didn't like

1:20:05

this idea. And and ten women

1:20:07

who have been so and a

1:20:09

third. And. So mistreated.

1:20:12

In. Madison and and Patreon and

1:20:14

Scion then think a lot

1:20:16

of i work really is

1:20:18

about trying. To. Help power

1:20:21

but also provide clarity that is

1:20:23

a reason for thing. I feel

1:20:25

special in biology. Very few things

1:20:27

happened by chance. They

1:20:30

think it's It's nice to know that.

1:20:32

Does happen. The Menopause brain

1:20:35

is via is not your imagination.

1:20:37

You're not going crazy. There's.

1:20:39

Something that is effectively happening

1:20:41

inside your hand. They were

1:20:44

now trying to understand. The

1:20:46

brain is effectively changing That

1:20:48

can provoke center to the

1:20:51

can be super scary. So

1:20:53

many women. Come. To

1:20:55

us because they are terrified that

1:20:57

they might be experiencing an early

1:20:59

onset dementia. You. Know and

1:21:01

it's a shame. The reassuring to hear. Is

1:21:04

that women are point and as talk

1:21:06

about how you can feel better. Thirteen.

1:21:09

That's important but if the wanted to look

1:21:11

at a positive. And. Really

1:21:14

provide some clarity and balance.

1:21:16

There isn't. Know

1:21:18

It and then appointed becoming more

1:21:20

popular. And. Companies are

1:21:22

tied to target and deposit when then,

1:21:25

and social media is no talking about

1:21:27

man opposed to the tendency to overeat.

1:21:29

Medicalized that and they had a bit.

1:21:31

And to talk about men, Apologists and

1:21:34

estrogen deficiency syndrome can tell you how

1:21:36

much I hate that definition. We use

1:21:38

it in science scientifically speaking if is

1:21:41

a term, but if you hear it

1:21:43

and you're not a scientist or a

1:21:45

cliche as a woman, is they telling

1:21:47

you it a baby? Can a sec.

1:21:50

Threat you I been gnostic. Does.

1:21:53

Is it does is Alive Transition. And

1:21:55

I to say it's just another tune. Do we?

1:21:58

We learn to dance to? Concluding

1:22:00

other that we learn to dance to.

1:22:02

Man than anyone knew it. We've

1:22:05

been at my friend immense treatment

1:22:07

monthly. nothing. From

1:22:09

an area. And dancing aligned. With

1:22:13

olive fragments is that we're not. that this is

1:22:15

something we can handle. And. We had

1:22:17

the tool and the research in the sky

1:22:19

In a Research and Science are coming. To.

1:22:22

Help The heck? Said.

1:22:24

It's I ever hit. While

1:22:27

it's amazing, I think you're getting a voice

1:22:29

to a lot of women who probably feel

1:22:31

voiceless. And. Here.

1:22:35

And so I commend you for your work.

1:22:37

And I love women. I'm a huge fan

1:22:40

of women. I love femininity and so er,

1:22:43

I mot. I think

1:22:45

is important. Topic. And.

1:22:50

And it's not just about men upon,

1:22:52

it's really about understanding how. A

1:22:54

Brains Work. You. Know that

1:22:57

like that's why I keep talking

1:22:59

about it. Sleep he said it

1:23:01

is clear is puberty pregnancy men

1:23:03

apart physically if part the distinction

1:23:05

kenya different aspects of being a

1:23:07

woman. And having of reproductive

1:23:10

system that is intrinsically wired to

1:23:12

work with your brain. Yeah,

1:23:17

I mean that's a huge

1:23:19

your way more complex and

1:23:21

we are. So I'm just

1:23:23

happy that on the someone

1:23:25

advocating for the the fairer

1:23:27

sex in science. Which.

1:23:30

Is why you've been doing. You know, for your

1:23:32

career, so it doesn't. Yeah, I'm so, so grateful.

1:23:34

And you've got a foreword by a mutual friend,

1:23:36

Maria Shriver on the cover. Yes,

1:23:39

Season. A This is the best

1:23:41

A And so and so fortunate

1:23:43

that she decided to raise. His.

1:23:46

Book Saturday Dec sixteen.

1:23:49

And. I guess make it like China.

1:23:51

Yes, she's about in. Areas such as

1:23:53

Strong As a Kid silliness held

1:23:55

and she was able to convince

1:23:57

the President had a United States.

1:24:00

To see that it was in

1:24:02

the news a two weeks ago?

1:24:04

Know? Yes! And so. And President

1:24:06

Biden actually his why is Just

1:24:08

launching. An. Initiative: The

1:24:10

target Women's Health and

1:24:13

Research Day Understand. The

1:24:16

women's health especially women brain health

1:24:18

is one of them are under

1:24:21

researched and under funded fields and

1:24:23

Madison as so Now it basically

1:24:25

monday said the Dna age has

1:24:27

to provide. The.

1:24:30

Hands. Of why it

1:24:32

is under funded and. Strategies.

1:24:35

To. Come. Up with a

1:24:37

plan and solution and really change that in the

1:24:39

next. Act. Many years. Said.

1:24:42

Or three laminar with maria. That.

1:24:44

Is a misused. In Asia for the

1:24:46

center of us is the Hershey.

1:24:48

Very nervous is so convincing an

1:24:50

inner? She's such a powerhouse. Yeah,

1:24:52

there is such an honor. Foods.

1:24:54

Which the garlic? And with her she's got some

1:24:56

connections. So. Have plenty

1:24:59

of such such a good

1:25:01

person. Yeah, Love Murderer. May

1:25:03

be when you see so you get. To.

1:25:05

Throw Triborough family by parole in

1:25:08

the other, A wonderful. Harm.

1:25:11

Or thanks for common and. Or thank you for listening.

1:25:13

There was a lot of women's health and. I

1:25:15

love it when it's done a level

1:25:18

of I'm genuinely do love it and

1:25:20

are super super important so thank you

1:25:22

so much! Are working people find you

1:25:24

on social media? Were heroes of media.

1:25:27

Instagram Instagram Say yeah Doctor

1:25:29

Mass kind of a D

1:25:31

R. As county mocha

1:25:33

or my website. On your

1:25:35

website, County that com and your books

1:25:37

available everywhere. Progress old that pick it

1:25:40

up. You guys Menopause Brame New Science

1:25:42

empowers women to navigate the pivotal transition

1:25:44

with knowledge and conference. I love it.

1:25:46

Think you know that Lisa. Thank you

1:25:48

guys are listening. Share this episode of

1:25:51

Friends Loved Ones. People in your lifetime

1:25:53

may benefit from it. Liberating Interview for

1:25:55

the show on your podcast. Have a

1:25:57

choice catch on the next episode p.