The Hilarious World of Depression

A Comedy podcast

A show about clinical depression... with laughs? Well, yeah. Depression is an incredibly common and isolating disease experienced by millions, yet often stigmatized by society. The Hilarious World of Depression is a series of frank, moving, and, yes, funny conversations with top comedians and funny creative people who have dealt with this disease, hosted by veteran humorist and public radio host John Moe. Winner of the Webby Award for Best Comedy Podcast. Join guests such as John Green, Russell Brand, Margaret Cho, Wayne Brady, and Wil Wheaton to learn how they've dealt with depression and managed to laugh along the way. If you have not met the disease personally, it's almost certain that someone you know has, whether it's a friend, family member, colleague, or neighbor. Depression is a vicious cycle of solitude and stigma that leaves people miserable and sometimes dead. Frankly, we’re not going to put up with that anymore. The Hilarious World of Depression is not medical treatment and should not be seen as a substitute for therapy or medication. But it is a chance to gain some insight, have a few laughs, and realize that people with depression are not alone and that together, we can all feel a bit better. The Hilarious World of Depression is made possible by a grant from HealthPartners’ and its Make It Okay campaign which works to reduce the stigma of mental health.

Recent Episodes


The show busts out of studios and quiet intimate spaces for an on-stage performance at the Dakota Jazz Club in Minneapolis. Comedian Mike Brown joins us for plenty of comedy and conversation. We even bust out a few games where you can play along and see if you can tell a Pokemon from an …

Not Enough Ratings

Although she comes across as confident and happy on her incredibly successful YouTube channel, Hannah Hart has plenty of experience with insecurity and misery in her life. Growing up, she faced severe poverty, hunger, and dealing with a mother who was mentally ill. Still, she made it into a good …

Not Enough Ratings

It's hard to settle on a musical description for Ted Leo. We ended up going with "if The Beach Boys were '80s skateboarders" to summarize his melodic intense post-punk sound. Similarly hard to nail down is whether Ted's longtime issues with depression and anger stem from his brain's built-in wiring …

Not Enough Ratings

Rachel Bloom has never moved across the country to chase a boy like Rebecca Bunch did. Rebecca is the character Rachel plays in "Crazy Ex-Girlfriend," the hit show she co-created and stars in on The CW Network. But Rachel does have a long history of messed up romantic relationships -- plus …

Not Enough Ratings

In one of the last interviews he gave, Reggie Osse, aka Combat Jack, talks about the connection between the status of the African-American man in contemporary society, the changing role of masculinity in hip-hop culture, and mental health. Osse was an important figure in hip-hop as a lawyer, …

Not Enough Ratings