Yusuke Shimakawa (Institut Pasteur) discusses the development and evaluation of a simple score for hepatitis B treatment eligibility in Africa.Read the full article:https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00449-1?dgci

Mads Israelsen on validating the new steatotic liver disease nomenclature in people with excessive alcohol intake

Mar 12th, 2024 16m 39s

Mads Israelsen (Odense University Hospital) discusses a study to validate the new nomenclature of steatotic liver disease in patients with a history of excessive alcohol intake.Read the full article:https://www.thelancet.com/journals/langas/art

Louise Dye on the role of expectancy and gluten in non-coeliac gluten sensitivity

Mar 1st, 2024 23m 19s

Louise Dye (University of Leeds) discusses a trial exploring the role of expectancy and gluten ingestion on symptoms in people with non-coeliac gluten sensitivity.Read the full article:https://www.thelancet.com/journals/langas/article/PIIS2468-

Tzu-Chan Hong on the primary antibiotic resistance of Helicobacter pylori in the Asia-Pacific region

Dec 19th, 2023 14m 40s

Tzu-Chan Hong (National Taiwan University Cancer Centre) discusses a systematic review and meta-analysis on primary antibiotic resistance of Helicobacter pylori between 1990 and 2022 in the Asia-Pacific region.Read the full article:https://www.

Sarah Moen on metachronous colorectal cancer risk according to Lynch syndrome pathogenic variant after colectomy

Nov 29th, 2023 14m 45s

Sarah Moen (Erasmus University Medical Center) discusses a retrospective cohort study examining the risk of metachronous colorectal cancer after partial or extensive colectomy in carriers of different pathogenic Lynch syndrome variants.Read the

Anna Emilie Kann on the causes of mortality in patients with alcohol-related liver disease

Oct 12th, 2023 16m 19s

Anna Emilie Kann (Zealand University Hospital, Denmark) discusses a population-based study done in Denmark exploring the causes of mortality in patients with alcohol-related liver disease.Read the full article:https://www.thelancet.com/journal

Robert Krouse on surgical versus non-surgical management of malignant bowel obstruction

Sep 13th, 2023 16m 31s

Robert Krouse (University of Pennsylvania) discusses the pragmatic S1316 trial of surgical versus non-surgical management for patients with malignant small bowel obstruction.Read the full article:https://www.thelancet.com/journals/langas/articl

Marc Rothenberg on a trial of benralizumab in eosinophilic gastritis

Aug 10th, 2023 14m 29s

Marc Rothenberg (University of Cincinnati College of Medicine) discusses a new trial assessing the efficacy and safety of benralizumab in patients with eosinophilic gastritis, and how the surprising findings might change our understanding of eo

Michael Pavlides on non-invasive tests for predicting clinical outcomes in non-alcoholic fatty liver disease

Jul 12th, 2023 17m 41s

Michael Pavlides (University of Oxford) discusses work by the LITMUS Consortium on the prognostic performance of non-invasive tests in patients with non-alcoholic fatty liver disease.Read the full article:https://www.thelancet.com/journals/lang

Jasmohan Bajaj on global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis

Jun 7th, 2023 12m 48s

Jasmohan Bajaj (Virginia Commonwealth University and Central Virginia Veterans Healthcare System, Richmond, VA, USA), on behalf of the CLEARED Consortium, discusses a prospective observational cohort study examining global disparities in mortal

Adelina Artenie on the incidence of HIV and HCV in people who inject drugs

May 10th, 2023 17m 15s

Adelina Artenie (University of Bristol, UK) discusses a systematic review and meta-analysis exploring the incidence of HIV and HCV among people who inject drugs, and associations with age and sex or gender. Read the full article:https://www.the

Johan Burisch on the costs of inflammatory bowel disease in high-income settings

Apr 12th, 2023 20m

Johan Burisch (Copenhagen University Hospital, Denmark) discusses the findings and recommendations of The Lancet Gastroenterology & Hepatology Commission on the cost of inflammatory bowel disease in high-income settings.Read the Commission here

Edouard Louis on the SPARE trial of infliximab or immunosuppressant withdrawal in Crohn’s disease

Feb 8th, 2023 21m 30s

Edouard Louis (University Hospital CHU of Liège) discusses the SPARE randomised controlled trial of infliximab or concomitant immunosuppressant withdrawal in patients with Crohn’s disease.Read the full article:Withdrawal of infliximab or concom

Paula Ghaneh on the ESPAC5 trial of neoadjuvant therapy in borderline resectable pancreatic cancer

Jan 23rd, 2023 20m 20s

Paula Ghaneh (University of Liverpool) discusses the ESPAC5 randomised controlled trial of short-course neoadjuvant therapy compared with immediate surgery for patients with borderline resectable pancreatic ductal adenocarcinoma. Read the full

Dan Turner on vedolizumab in children with IBD

Jan 6th, 2023 14m 51s

Dan Turner (Shaare Zedek Medical Center) discusses the VEDOKIDS study on the safety, effectiveness, and dosing of vedolizumab in children with IBD.Read the full article:Outcomes, dosing, and predictors of vedolizumab treatment in children with

Simon Baunwall on faecal microbiota transplantation for first or second Clostridioides difficile infection

Nov 9th, 2022 15m 21s

Simon Baunwall (Aarhus University Hospital) discusses the EarlyFMT trial, a randomized placebo-controlled trial of faecal microbiota transplantation for first or second Clostridioides difficile infection.Read the full article:Faecal microbiota

James Alexander on immune responses to COVID-19 vaccination in patients with IBD

Oct 5th, 2022 13m 48s

James Alexander (Imperial College London) discusses the latest findings from the VIP case-control study, which is investigating COVID-19 vaccine immune responses in immunosuppressed patients with inflammatory bowel disease.Read the full article

Filip Knop on liraglutide for bile acid diarrhoea

Sep 7th, 2022 15m 2s

Filip Knop (University of Copenhagen) discusses a trial of liraglutide versus colesevelam for the treatment of bile acid diarrhoea.Read the full article:Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrh

Edward Kim on radiation segmentectomy for unresectable very early to early stage hepatocellular carcinoma

Aug 4th, 2022 14m 6s

Edward Kim (Icahn School of Medicine at Mount Sinai) discusses the single-arm RASER study of radiation segmentectomy for patients with unresectable very early to early stage hepatocellular carcinoma.Read the full article:Radiation segmentectomy

Joep Ijspeert on serrated polyp detection and risk of interval post-colonoscopy colorectal cancer

Jul 6th, 2022 10m 26s

Joep Ijspeert (Amsterdam University Medical Center) discusses a population-based study exploring the detection of proximal serrated polyps and interval post-colonoscopy colorectal cancer risk.Read the full article:Serrated polyp detection and r

Elise Meima-van Praag on surgical closure for Crohn’s disease perianal fistulas

Jun 14th, 2022 9m 50s

Elise Meima-van Praag (Amsterdam University Medical Centre) discusses the PISA-II trial, investigating short-term anti-TNF therapy with surgical closure versus anti-TNF therapy for perianal fistulas in Crohn's disease.Read the full article:Shor

Juan Pablo Arab on NAFLD public health policies in the Americas

May 9th, 2022 17m 6s

Juan Pablo Arab (Catholic University of Chile) discusses the current burden of NAFLD and the landscape of public health policies related to the disease in the Americas.Read the full article:The establishment of public health policies and the bu

Sarah Blach on hepatitis C virus epidemiology

Apr 6th, 2022 8m 57s

Sarah Blach (CDA Foundation) summarises the latest analysis of global hepatitis C virus epidemiology and cascade of care by the Polaris Observatory HCV Collaborators.Read the full article:Global change in hepatitis C virus prevalence and cascad

Sunil Solomon on a minimal monitoring approach for hepatitis C virus infection

Mar 23rd, 2022 15m 2s

Sunil Solomon (Johns Hopkins University) discusses a study of a minimal monitoring approach for treating patients with hepatitis C virus infection.Read the full article:A minimal monitoring approach for the treatment of hepatitis C virus infect

Rupert Leong on oral faecal microbiota transplantation in ulcerative colitis

Mar 9th, 2022 13m 43s

Rupert Leong (University of Sydney) discusses a new double-blind, randomised, placebo-controlled trial of oral faecal microbiota transplantation for patients with active ulcerative colitis.Read the full article:Lyophilised oral faecal microbiot