Rejuvenation biotech is a new industry forming around the theme of life extension technologies. This episode provides a broad look at the state of the industry, its most promising life extension technologies and their potential timelines.
Microbiome testing can be confusing: many companies, different technologies and a lack of standards make it hard to get actionable insights from the data. Find out how technologies and labs differ and what information is actionable from today's
Looking at an example of Machine Learning applied to functional medicine with the goal of helping athletes optimize performance. The question - with the help of artificial intelligence, can a 7-minute questionnaire identify physiological weakne
What is carbohydrate intolerance? Do each of us have a personal tolerance or intolerance of carbohydrates? Does this also vary by source of carbohydrate? Learn how evolutionary tools may explain appetite regulation and carbohydrate metabolism a
Is your glucose metabolism driven by your personal microbiome? Recent research reveals how the microbiome influences blood glucose, weight gain and weight loss. And how the new company, "Day Two", is using microbiome sequencing data to provide
Recent investigations have shown supplements to not always contain what they say they do. Or at other times to have unwanted contaminants such as heavy metals. Learn to use 3rd party lab testing to select supplements that contain the active ing
Micronutrient status is a foundation of health, performance and chronic disease minimization. This episode looks at how to optimize fat soluble micronutrients status.
In this episode we look at ensuring micronutrient status. Ensuring your body
Ketone bodies, whether gained from fasting, keto diets, MCTs or exogenous ketones have many potential applications with benefits ranging from performance, to health, to longevity and mitigating symptoms and risks of certain diseases.
Putting the body into ketosis and controlling blood glucose levels may prove to be effective therapy against certain cancers. This real case reveals one aggressive self-experimenter who used a combination of the ketogenic diet, fasting and othe
Most of us have non-optimal blood glucose regulation today.The impact? Reduced performance, and reduced longevity. We wrongly assume that it's only diabetics that are exposed to these issues. This episode explores using continuous glucose monit
Part 3 in our series of Fasting Self-Experiments. In this longer 10 day water fast I tracked results with a broad set of biomarkers (ketones, glucose, weight, hormones and cognitive performance panels).
This is a long post - if that scares you
A look at how to accurately quantify your cardiovascular fitness in order to optimize endurance sports or your cardiovascular health. Is VO2Max the gold standard? Are the metrics in the current "fitness trackers" useful for this goal?
In this e
Heart disease affects 50% of the U.S. population in their lifetime. Learn how to accurately quantify your personal heart disease status and risk, and if necessary, take clear actions to reduce that risk by eliminating plaque in the arteries.
Meditation - ever more popular as studies pile up proving its benefits. However, how do you assure yourself that you gain the same benefits with your meditation practice? Muse Calm is a neurofeedback device that promises accurate feedback on th
What is genetic testing able to do and not do with current services? We talk with one of the top genetic lab services to understand how technologies differ in accuracy and where it is working, where it is not yet ready and why.
In this episo
What defines human microbiome health? The co-founder of American Gut Project discusses the differences we've found in the gut microbiome and how it influences our health. We look at tools and lifestyle choices that have been shown to change the
Water fasting or ketogenic therapies may be effective with some cancers, and not with others. Learn about the PET scan and how it can provide insights into whether a cancer is likely to be responsive or not to the water fast tactic we've covere
An in-depth look at using heart rate variability biofeedback with slow breathing to reduce stress, enhance athletic performance and provide therapeutic support for some chronic health issues.
Heart rate variability biofeedback is being used pr
A look at a collection of high impact endurance tools and tactics - and the top biomarkers to watch for optimization. Vetted by an endurance athlete with years of experiments and competitions behind him.
Today's episode is about endurance trai
We strive for the best mental performance but how do you know if your routines (sleep patterns, coffee habits, etc.) are helping or hurting? The Quantified Mind is a web-based project that allows you to quickly check your cognitive function in
Can physicians improve health outcomes using new self-tracking tech with their patients? Or is the tech still too inaccurate or impractical? We take a hard look at the reality and potential with a physician testing quantified self practices in
Is the Fast Mimicking Diet (FMD) an easier way to get the benefits from fasting? In this self experiment I tracked lean muscle mass gains, improved metabolism (ketones, glucose), strong regeneration signaling (IGF-1) and a couple of downsides.
Oxaloacetate is an important metabolic intermediate in the energy pathway of the mitochondria. Recent case studies support the use of oxaloacetate as a nutritional supplement to help regulate blood glucose levels, potentially support longevity
Mitochondria, the power plants of our body, get damaged through aging and other stressors. Lipid Replacement Therapy (LRT) is a tool being used to repair part of this damage to mitochondrial membranes, and can help people recover and optimize t
A walk-through of the 5-day water fast with the tracked results (ketones, glucose, weight) and the practical do's and don'ts to make the most of the experience.
I'm not a fan of cancer. The only people I've lost in memory - my grandfather and o
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