In this video i spoke with Dr Brandon Berry, a current Post-Doctoral fellow at the University of Washington, where he is developing and using tools to understand the function of mitochondria and their link with diseases and aging. Here, we discuss these interests further and the results from his latest publication one tool, termed 'mitochondria-ON', extended worm lifespan. 'Mitochondria-ON' rejuvenates the mitochondrial membrane potential when exposed to light and all-trans-retinal using optogenetics.
Find Brandon on Twitter - https://twitter.com/mitobrandon
Research papers - Berry, B.J., Vodičková, A., Müller-Eigner, A. et al. Optogenetic rejuvenation of mitochondrial membrane potential extends C. elegans lifespan. Nat Aging (2022). https://doi.org/10.1038/s43587-022-00340-7
Optogenetic control of mitochondrial protonmotive force to impact cellular stress resistance https://www.embopress.org/doi/full/10.15252/embr.201949113
Berry, B.J., Kaeberlein, M. An energetics perspective on geroscience: mitochondrial protonmotive force and aging. GeroScience 43, 1591–1604 (2021). https://doi.org/10.1007/s11357-021-00365-7
Find me on Twitter - https://twitter.com/EleanorSheekey
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