“If one more person brings me another pilot, they're getting fired," one C-level supply chain executive told Zero100 — and they’re far from alone in their frustration. Most companies are drowning in AI projects that never scale because they’re optimizing functions in isolation while ignoring how decisions actually flow across the business. The solution? PowerThreads: end-to-end AI-enabled workflows that connect sensing, deciding, and acting across organizational silos.

This week, VPs, Research & Advisory Lauren Acoba, Jenna Fink, and Geraint John break down the five core PowerThreads driving 95% of enterprise value, share a $300M sourcing transformation that required five years of unglamorous foundation-building, and explain why optimizing one bottleneck without understanding the full system often just moves the problem downstream.