The stories behind how science is done. It's a great premise as a scientist and a generally well-done podcast. The stories are told at a popular level, so there's no need to have specialized knowledge. And they're told in an engaging, often fun way. Good times.
My only minor complaint is that, since the show is half an hour long, they often don't dig as deeply as they might or push back against some of the things interviewees say that are kind of sketchy. But it's not a journalism show, as such, it's telling the stories, so that's also probably a little fair.