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Vital Science
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Vital Science
Vital Science
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Imagine giving birth to a baby girl and noticing pieces of skin missing from her body almost immediately. For Sharmila Nikapota, this was the case with her firstborn, Sohana. Genetic testing revealed that she was one of the over 500,000 people
Stimulant use in the United States has exploded into a nationwide crisis, as deaths and emergency room visits resulting from methamphetamine and cocaine use are rising at an alarming rate.The overall substance abuse disorder crisis is further e
At Mission Therapeutics, Sarah Almond serves as their Head of Pharmacology, but she wears many hats to help develop potential treatments for neurodegenerative conditions. Their main area of focus centers around research into deubiquitinati
Opioid use in the United States has exploded into a nationwide crisis. Users who want to get clean and rid themselves of methamphetamine, cocaine, and/or fentanyl often find it difficult, essentially “chaining” themselves into a cycle of drug
When he founded Cure Rare Disease in 2018, Rich Horgan was primarily focused on finding a treatment for his younger brother Terry, who had an ultra-rare form of Duchenne Muscular Dystrophy (DMD). Suffering from a disease that has no cure, Ter
For the 850 million people around the world suffering from chronic kidney disease, the grind of dialysis treatment can wear them down in more ways than one. Dr. Andy Herbert, co-founder of Invizius, is out to change that. This five-year-old
Over the past 12 months, we have shared some remarkable stories from the scientific community, but three of the most impactful have come from “Disruptors” in their respective fields. Relive these stories with our hosts on the year-end edition o
When Maria Picone’s daughter was diagnosed with Prader-Willi Syndrome (PWS), she turned to the internet for answers. What she found was an online community of caregivers sharing their experiences with PWS, giving her comfort and direction wit
Imagine a world where your child has a rare disease that’s so rare, it doesn’t have a name and only a handful of people around the world have a similar condition. It can leave you feeling helpless and alone knowing the odds are stacked against
18-year-old Emily Whitehead aspires to be a writer, but nothing could have prepared her for the plot twist that struck her as a child. In the space of just 24 hours, five-year-old Emily suffered from various symptoms that culminated in a diag
For decades, researchers have utilized animal models to help predict the effects of a drug compound in humans. With recent advances in technology and the passage of the FDA Modernization Act 2.0, researchers are increasingly looking at new me
Spinocerebellar ataxia type 3 (SCA3) is a neuromuscular disease affecting just 50,000 people in the United States, including three generations of the Klassen family. Greg Klassen, his father, and his son have all been diagnosed with this rare
The effects of Angelman Syndrome (AS) on young children are debilitating. From an early age, they face an uphill battle with this neurogenetic disease’s unrelenting symptoms, including seizures, cognitive impairments, and loss of motor function
When patients face the diagnosis of a rare disease, they face a costly, uphill battle to develop a treatment for their condition… that is, if they ever do. Dr. Stanley Crooke is aiming to change that. As the CEO of n-Lorem Foundation, his mis
Imagine being diagnosed with an incurable rare disease before ever being born. This is the reality that Evie faced when she was diagnosed with hypophosphatasia, a condition impacting bone growth, breathing, and mobility, and often gives patient
Could it be possible to regenerate neurons in the human body? It’s a question that has driven Dr. Wise Young for over 40 years. He’s dedicated his career to researching spinal cord injuries and how to develop a treatment for them. Along the wa
Recent advancements in research has led to the development of effective therapeutics to combat neurodegenerative diseases, giving patients a renewed sense of hope there will ultimately be a more effective treatment.CEO Lisa Deschamps and her te
As we close in on the end of 2022, we’ve had the privilege to interview some amazing people who are doing great work with drug discovery. Join Gina Mullane and Todd Poley as we reflect on some of the memorable moments and guests from this sea
Spastic Paraplegia 50 (SPG50) is a neurodegenerative and neurodevelopmental disorder that is known to affect only 80 people around the world, including just one person in Canada. Unfortunately for Terry Pirovolakis, it happens to be his son,
For Valerie Estess, finding a cure for ALS is personal.Her sister, Jenifer, was diagnosed with this crippling disease in 1998, which led to the founding of Project ALS, a nonprofit designed to raise awareness and eventually find a cure. Nearly
What happens when you combine an industry-altering, AI-powered platform with a leading CRO's preclinical expertise? That’s what Valo Health and Charles River are answering with the introduction of Logica™. This revolutionary platform aims to a
Drug developers face long odds and complex regulatory challenges when it comes to crafting a suitable candidate. In fact, only one of every 10 drug candidates gain regulatory approval, and when they do, it takes an average of 14 years and costs
Aled Edwards’ vision of science is set to shake the foundation of drug discovery and development as we know it. The Director of M4K Pharma and CEO of the Structural Genomics Consortium is leading the charge for a more open scientific approach
A medic by trade, Mark Kotter has always held a particular interest in neuroscience and stem cell research.As founder and CEO of bit.bio, he's overseen the development of a unique approach to "reprogram" stem cells and change them into consiste
Imagine a gene therapy treatment that gives drug-resistant focal epilepsy patients more control over their seizures and ultimately improve their quality of life?We sat down with Karin Agerman to discuss this possibility and discovered that her
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