0:04

I'm. Jj. Bridge and P H

0:06

Drop sorry Mom turned four time

0:09

New York Times bestselling author. Yes,

0:11

I'm a Certified Nutrition Specialist fitness

0:13

Hall of Famer and they speak

0:15

it health conferences and trainings around

0:17

the globe, but I'm driven by

0:19

my insatiable curiosity and level sides

0:22

to keep asking questions, digging for

0:24

answers, ensuring the information I uncover.

0:26

With as many people's they can and

0:28

that's why I created the Well. Beyond

0:30

Forty Podcast to synthesize and

0:33

simplify the science of how.

0:35

Into actionable strategies to help you

0:37

thrive. In each episode will talk

0:39

about what's working in the world of

0:41

wellness from personalized nutrition and healing. Your

0:44

metabolism to healthy aging and prescriptive

0:46

fitness join me on the journey

0:48

to better health so you can.

0:50

Love how you look and feel right now

0:52

and have the energy! To play full out

0:54

at one hundred. I

0:58

have one of my favorite guess back

1:01

and what super fun as I have

1:03

him in person. Some here to metabolic

1:05

help conference and I happen to notice.

1:08

That doctor Rick Johnson was speaking

1:10

and I went Holy Smokes! I

1:12

finally get to meet him in

1:15

person and we just recorded and

1:17

Amazing! Podcast where we really

1:19

looked at all the different

1:22

theories about why. We gain

1:24

fat or why it's hard

1:26

to lose fat And there's

1:28

for predominant Furious And what

1:31

Rick did was go into

1:33

every single one of those

1:35

theories, how they work, what

1:37

the hypothesis is, what is

1:39

right about them. But then

1:41

he went into the unifying

1:44

theory that brings them all.

1:46

Together And what's important about that

1:48

unifying theory is, don't we talk

1:50

about what you can do to

1:52

to fix. That and you know it's

1:54

cool is it's actually. Pretty simple,

1:56

so. We're going to be talking

1:58

about that. I've got doctor. Rick Johnson with

2:01

me in the house. He is a

2:03

professor of medicine at the University of

2:05

Colorado. For the last twenty years he's

2:07

been a clinician, fianna, medical sciences and

2:09

he's recognized internationally for his work on

2:11

sugar. And by the way, when I

2:13

was the sugar impact diet this was

2:16

what I went. I went and didn't

2:18

read all of which research. She was

2:20

like My my man. He was my

2:22

guru before he knew me. To

2:25

so very interesting work in fructose

2:28

and uric acid. He's been funded

2:30

by the Nih. He is published

2:32

over. Five hundred academic panelists.

2:34

He's. Written several books from fact the

2:37

latest when you definitely want to get grab

2:39

it was published and twenty twenty. Two

2:41

and those nature of wants

2:43

us to be Now Most

2:45

recently she has taken on

2:47

the position of. The

2:50

lead with. Cs and the

2:52

Director of Science for the lead medical

2:54

scientists over it or x sugar me

2:56

to put information art sugar in the

2:58

show Notes: I'm a fast. With.

3:00

Horace Sugar. My buddy Doctor David Perlmutter

3:02

turned me onto them. It is a

3:05

novel. Are you a company that is

3:07

than most incredible research will be talking

3:09

about that towards. And on

3:11

and a dissenting now that

3:13

I'm actively putting into my

3:15

diet and. As we talk about,

3:17

you'll learn why you want to. Do. That

3:19

and a Porsche. Learn some delicious

3:21

way to do that to swap

3:23

file have all of that in the

3:26

show. Notes at Such a virgin.com

3:28

Forward/ Rec Center virgin.com Accord

3:30

sauce. Rick and I will

3:32

be right back with them

3:34

to Richardson Davis. I've

3:42

got Doctor Rich Johnston with me in the house.

3:45

In my sweet I mean never let you

3:47

out of I'm so excited because we to

3:49

this isn't interview number. Three years. And

3:52

I just got to listen. To your lecture today

3:54

at Metabolic How. Someone you I

3:56

took literally. Copious. Notice

3:58

us. and them I was

4:00

grabbing all your slides because your slides

4:02

are fantastic. But

4:04

you have such a gift to be

4:06

able to explain complex

4:09

pathways into like,

4:11

oh, okay, I see exactly how that

4:13

leads to the situation. And I love

4:16

where you're going right now with how

4:20

low ATP can

4:22

create obesity. So I think we're

4:24

going to unpack the fructose story

4:26

here. And

4:29

what I really want to get into

4:31

is the four different theories right now

4:33

for why we gain weight and then

4:36

unpack how really you've kind of linked

4:39

them all into one unifying idea that

4:42

we can do something about and actually do

4:44

something about pretty easily, which

4:46

is what's so exciting about it. I

4:48

love super actionable things that one

4:51

simple swap that you

4:53

literally won't notice the difference from, right,

4:56

can completely change everything. So

4:59

if you're hearing this going, okay, I'm in,

5:01

this is going to be fantastic. So

5:03

let's talk first about the

5:05

like, what are these the diet wars,

5:09

the diet wars out there of the different

5:11

ideas of why we can't lose weight or

5:13

why we gain weight? What are they? Well,

5:16

there's four major diet theories

5:18

that have been out there.

5:21

And the first one is

5:23

the well, actually, if you go

5:25

way back. If you

5:27

go way back to like the early 1900s,

5:30

there was

5:32

this association of obesity with

5:34

sugar and, you

5:36

know, like sugar was

5:38

introduced to the island of Nauru, a

5:40

Pacific island in the 1920s. It

5:43

was sugar was introduced there and

5:46

the people started eating a lot of sugar, like

5:48

up to half a pound a day. And

5:52

diabetes was first seen there like 1925 or 26. And

5:56

then obesity just erupted. But

5:58

there was this association. where when sugar

6:01

was introduced into a culture, there

6:03

was this development of obesity. And

6:06

so in the 1920s,

6:08

it was thought that obesity

6:10

was a sugar disorder. And

6:12

same with diabetes and favorite

6:14

Banting, the guy that discovered

6:17

insulin. You know,

6:19

he actually said that he thought

6:22

the cause of diabetes, that type

6:24

two diabetes was too

6:26

much sugar, refined sugar. Now, this

6:29

sugar hypothesis evaporated

6:34

when Elliot Choslin, you

6:37

know, published a paper where he

6:39

said, Hey, you know, I agree. People

6:42

are eating sugar, sugar is associated with

6:44

obesity. There's no doubt sugar is associated

6:46

with diabetes, no doubt. But

6:49

the real problem is that people are

6:51

eating too much. And

6:53

he coined the term over nutrition.

6:55

And when was that? Well, around

6:58

1926. Okay. And

7:00

but he really, it was in the early 1930s,

7:02

where he really pushed it. And

7:05

he said, you know, obesity is from eating

7:07

too much, and

7:09

exercising too little. And

7:11

this is the cost. And

7:14

this is also driving diabetes. And

7:16

the world looked at him, they said, you

7:19

know what, there really

7:21

is people are eating a lot more, it

7:23

seems. And there really is seems

7:26

to be we're exercising less, we got

7:28

cars, you know, we got all these

7:30

things. And so the this

7:32

belief just took over. And

7:35

then later, you know, because

7:38

fat is the most

7:41

dense calories per gram, it's

7:43

like twice the amount of calories,

7:45

a spoon of fat is

7:48

more than twice the calories of a spoon

7:50

of carbohydrate or a spoon of bread. So

7:53

fat had to be the driver

7:56

plus Fats in the

7:58

coronary arteries and fat is

8:00

the you know cause another cholesterol

8:02

plaques and so bad is

8:04

the culprit. Now that was that

8:07

was seventies eighties right? Well.

8:09

Was actually wasn't very before he

8:11

was a little before in the

8:13

sixties. Absolute. Keys Oh

8:15

yeah owners who is a get a

8:17

nutrition and he's her with a select

8:19

the I He says the fact that

8:21

it was. Really

8:24

did roosters they are really they

8:26

my grill and made his yeah

8:28

and so there is for a

8:30

long time was thought to be

8:32

fat but the the fat idea

8:34

started to disappear when all the

8:36

studies came out. challenge in it.

8:38

But the idea that we're eating

8:40

too much and exercise too little

8:42

still remains one of the major.

8:45

Theories. And then it's like. The.

8:47

National Institute of Health really has

8:49

pushed this married. Scientists

8:51

in at Oxford you know

8:53

various teams are university of

8:55

that's my bank account theory

8:57

that bank accounts very best.

8:59

So basically you do our.

9:02

With. Idea is. Were. Eating

9:04

too much. For. Exercise into

9:06

of on the extra energy. Has.

9:09

To be go over into fat. right?

9:12

The. Thing we don't look out there is that

9:14

it's very different where the calories come from

9:17

bright bright say don't care I mean even

9:19

if you stayed ice a clerk and took

9:21

some those calories away from say carbs and

9:23

put him over to protein. This.

9:25

Magic. What happened. That always say

9:27

so. So we have the bank account

9:29

model. Then I called the Chemistry Mob

9:31

model The Chemistry Lab model which is

9:33

is it is a carbs? Is that

9:35

insulin? Yes that is it an alien

9:38

specifically within their i would think Brickhouse

9:40

yes or a second I later on

9:42

down there at also be labeled on

9:44

but so we have that those so

9:46

the first one is the energy balance

9:48

and that the biggest arguments for is

9:50

that people really are you the morgue.

9:53

Per day than they were like to nineteen

9:55

sixty and and we are an extra moving

9:57

yeah see I guess. I think I say it's

9:59

it's. This is a really important.

10:01

Distinction be has. We've gotta look. When

10:03

we look at metabolism, we have you

10:06

know, basal metabolic rate? Than. We

10:08

have. Their. Make the effect of

10:10

food, Then we have. Exercise

10:12

and activity and we may all be

10:14

exercising but worse sitting our bus more

10:16

than ever is set which. Is as

10:18

seems more colored Spanish. Her should be

10:21

than even the exercise. So yeah,

10:23

you know we probably are moving

10:25

last. Okay, what's the next one?

10:27

So the the second big hypothesis

10:29

and this these first two are

10:31

the big ones. isn't the carbs?

10:33

insulin? Muslim? As. This

10:35

one is saying hey, you know

10:37

it isn't just about cowardice is

10:39

the type of couch. And

10:42

is really carbohydrates. And

10:45

when you. Eat

10:47

carbs. You. Stimulate

10:50

insulin. And. Hi

10:52

Insulin. Absolutely.

10:55

Drives fat. And.

10:57

So are is really all

10:59

about how much carbs you're

11:01

eating and that includes sugar

11:03

considered stimulates, insulin. But it

11:05

also includes things like what

11:07

we call high glycemic carbs

11:09

you know, rice, potatoes, Fred

11:11

serial. Foods. That most

11:14

people love. Hot. For

11:16

add Zebra Zero, zero. And

11:19

one I brushed and Sampras's yeah

11:21

yeah it's I literally growing up

11:23

every day after school my girlfriend

11:25

my would buy a loaf of

11:27

late big extra sour sourdough bread

11:29

every day. every day. For.

11:31

I've of bread so much that in

11:33

college my roommates gave me a low

11:36

for a bakery bread from as my

11:38

birthday and set of kate because I

11:40

love the hot bread will go butter

11:42

and. Ah, Yeah.

11:45

No, it's a it's true. people

11:47

like carbs. There. Is

11:49

an intrinsic like emails of glucose or a

11:51

sweets? What are we kind of hard wired

11:53

to do? Think that out and he met

11:55

why we're so see the bunch of it's

11:58

hibernate. as it does That's

12:00

coming, yes, that's probably right.

12:03

But anyway, so the carb insulin model,

12:05

it says it's actually not

12:07

just calories, it's

12:09

insulin. And the

12:11

point there is that if

12:15

you go on a low-fat diet, you're going to be

12:17

on a high-carb diet, and that isn't going to be

12:19

good. And one of the

12:21

things a low-carb diet does is

12:24

it really says that it's not

12:26

just driving obesity, it's driving diabetes

12:28

and all these other things, which

12:30

the bank account

12:32

model doesn't really account for

12:35

as easily. Well, the

12:37

thing you showed today that I thought was

12:39

really interesting, because the bank account people

12:41

will argue it doesn't matter if your

12:43

calories are restricted. But

12:45

what you showed today that was like, this

12:47

is so important is that you could still

12:49

have, you know, keep calories the same or

12:51

restrict calories if you shifted

12:54

so that you were eating a high-carb,

12:56

especially fructose-driven diet, you would have more

12:58

visceral adipose tissue, you would change your

13:00

body composition. So your weight would might

13:03

stay the same, but what your weight

13:05

was made up of would change dramatically, which

13:07

is a major problem. And if you start

13:09

to shift from muscle mass,

13:11

and now all of a sudden you're

13:13

getting more visceral adipose tissues, so now

13:15

you're moving lowering muscle, raising fat,

13:18

you will gain weight over time because your

13:20

metabolism is going to shift. You're

13:22

exactly right. What our group

13:24

is showing is that

13:27

when it comes to calories, higher

13:30

calories will lead to more weight

13:32

gain. But if you

13:34

give the same calories, but you restrict carbs,

13:38

you will get a lot of additional

13:40

benefits. If you

13:43

do equivalent calories, but

13:45

one group has

13:47

a lot of sugar, for example, you

13:50

can still induce diabetes, you

13:53

can still induce fatty liver. Yes,

13:55

and you can be clerically restricting

13:57

and still create those problems. sick,

14:00

which is wild. Sick is incredible.

14:02

Yeah, we can we can put

14:04

animals on a diet caloric

14:07

restriction. Actually, the

14:09

way we did this was sort of ironic.

14:13

We wanted to know if high

14:16

our data suggests that sugar is bad, and

14:18

that there's a component in sugar called

14:21

fructose. And that's what

14:23

is what's bad. And

14:25

we had we knew that fructose makes

14:27

you eat more. And that's why

14:30

you gain weight is you

14:32

you do eat more. So the energy

14:35

balance theory was corrupt in terms of

14:37

weight gain, because the

14:39

but it's driven by sugar, and

14:41

the fructose makes you hungry. And

14:44

then you eat more and then you gain

14:46

weight. But if we said to ourselves, what

14:48

if we didn't allow an animal to

14:50

eat more so that they all were eating

14:52

the same. So we decided to

14:54

do the experiment. And then Carlos, who's working

14:56

with me, happens to be

14:58

my brother in law, would

15:01

had all these animals on the same

15:04

amount of food in somewhere on a

15:06

sugar diet and somewhere on a control

15:08

that but he when

15:11

you when all the animals have to eat

15:13

the same, they all have to

15:15

eat the same as the one who eats

15:17

the least Carlos, but then the experiment without

15:20

really looking at what happened. But what suddenly

15:22

you realized that there was one animal that

15:24

was eating very little. And

15:26

so all the animals had to eat very little.

15:29

And it turned out that poor little guy

15:31

had cancer. Oh, no. So at the end

15:33

of the thing, we realized he had cancer.

15:35

That's why I was eating low. And

15:38

so he got thrown out of the experiment. But

15:40

all the other guys were eating way below

15:43

their normal food intake. But

15:46

one group was on high sugar, and one was

15:48

not. So it turned out

15:50

that when they're all eating the same amount,

15:52

and they're basically on a caloric restriction, You

15:55

know, there was no weight gain, of course, but the

15:57

weights stayed the same and the two groups because it

15:59

was. Wait, Is driven mainly

16:01

by calories but the last the guys

16:03

that were on sugar. After

16:06

three months. Every one. it

16:08

was diabetic. As get

16:10

gays, other guys on a

16:13

caloric restriction. Totally normal. The

16:15

ones that have a high sugar that ah

16:18

betty live. All. Had bad

16:20

Fabulous. They all had

16:22

high blood pressure. They

16:25

were. You know the had they insulin

16:27

resistance A had this function of their

16:29

eyelids. See another were that isn't insulin

16:31

a secret? it's. Are. And they

16:33

had visceral fat. Weight. Gain

16:35

correlates with getting diabetes. and

16:37

that's because almost everyone who

16:39

are you know I developed

16:41

metabolic syndrome that it's a

16:44

cluster. their weight goes after.

16:46

He. Became islam resistant but you can

16:49

separate see. This just shows that

16:51

while the bank account model might be

16:53

true in the way that yes you

16:55

were sir calories, you lose weight, it

16:58

doesn't show. What? Wait,

17:00

What is happening with so a

17:02

totally correct. So. So then

17:04

the point isn't to lose weight. The points

17:06

to get healthy. Yes, so that's why the

17:08

energy balance hypothesis does not solve the problem

17:11

as a And that's why a low carb

17:13

diets. To. But there's more.

17:15

there's more than deceased to models that

17:17

us to other ones. Are

17:20

there's recently at Chris to know be

17:22

who you probably have met on awkward

17:24

or known as by Chris I has

17:26

been promoting the idea. That.

17:28

It's not the increase in sugar

17:31

that's causing obesity, but rather than

17:33

as an increase in seed oil.

17:35

Cat lover your opinion on that?

17:38

Yes, hi, I'm so Seat or

17:40

else on earth he These are

17:42

like vegetable oils. And

17:44

their arm. Father.

17:47

Polyunsaturated fats, And.

17:50

Damn there's monounsaturated fat saturated

17:52

fats with all these different

17:55

types of fat. And.

17:57

A lot of people say.

18:00

That are fat is that. But.

18:02

Actually, we were really learned that

18:04

each sad as difference. And

18:07

of the omega three Fats. I

18:09

could get and salmon. That.

18:11

Those are very healthy. Oh my gosh,

18:14

they're healthy. And they actually. In.

18:16

Animal models. He. The

18:18

omega three can block some of the insects

18:20

of sugar. I mean that

18:23

omega threes good for the brain.

18:25

it's really does for the brain.

18:27

And fish oil or omega three

18:29

oils are walnut oil. ah

18:32

I thought walnut oil on

18:34

i'm salad sometimes. Sam.

18:36

And the of fish like that

18:38

during who read simple omega to

18:40

omega three is wonderful. And

18:43

it's so. We. Should all

18:45

be hearing more of it. but seed

18:47

oil tend to be omega six. Now.

18:51

And the and I a church If

18:54

you take a healthy person very healthy

18:56

person and you give them omega six

18:58

is sometimes hard to show that it

19:00

causes inflammation. A people think that omega

19:03

six can cause inflammation but as he

19:05

give it to someone who's sick it's

19:07

a little bit easier to and and

19:10

it turns out that omega six is

19:12

turned into things called prostate gland is

19:14

in also the it comes in it's

19:16

it's used to make substances and they

19:19

didn't press or glad and them are

19:21

bad. For us, a glance and

19:23

in in people with metabolic Syndrome.

19:26

They. Tended to make bad process Gladys

19:28

Soil when you're giving seed oil

19:31

to someone who's overweight or someone

19:33

who are under his insulin resistance

19:35

is gonna go around way I

19:37

don't. You think it is because

19:39

they already have their cup is

19:41

already for their already have low

19:43

grade inflammation? Yes. And so a

19:45

mega six like we need. Some Omega Six as

19:48

we need a maze or three. they need a balance

19:50

or bumps. and with a healthy person

19:52

probably they've got because you know

19:54

these are in your membranes so

19:56

they're probably good yeah and a

19:58

little bit isn't gonna change equation,

20:00

they don't have the low-grade inflammation.

20:02

They're not, they don't have excess

20:04

body fat. Right. So they're okay.

20:07

But you have this insulin resistant

20:09

person who's already got low-grade inflammation,

20:11

who's probably got a higher percentage

20:13

of six related to three. Yes. And

20:15

now you just tipped it over the

20:17

edge. Exactly what I'm saying.

20:19

Exactly what the way I view it.

20:21

And it's sort of like salt. So

20:24

if you're young and your kidneys

20:26

are normal, there's

20:28

not much data that salt is bad. People

20:31

can actually eat a fair amount of salt

20:34

and you won't see a rise in blood pressure.

20:37

Paradoxically, the people I see worried the most about

20:39

seed oil seem to me the people that don't

20:41

need to worry about it because they rarely get

20:43

it in their diet. And they're like, you can't

20:45

have any. I go, I don't think

20:47

we have to be that concerned with

20:49

it. I think I had a

20:51

great nutrition mentor early on who said, the sicker you

20:54

are, the farther back in your ancestry you should eat.

20:56

And it seems like to me, like no one should

20:58

be like purposely going out, you know, what I think

21:01

I'm going to do, I'm going to go have that

21:03

olive oil blend with the canola is probably rancid,

21:05

all have that. You shouldn't go try

21:07

to get that. But if you have a little bit

21:10

out somewhere, it's not going to throw you over the

21:12

edge. I 100%

21:14

agree because, you know, one of

21:16

the problems is being super dogmatic

21:18

about anything and then there's

21:21

no, no fun. And really, most of

21:24

these things are about

21:28

eating it in excess. So

21:30

even though I believe that fructose is

21:32

bad, I know that

21:35

like five or 10 grams of fructose

21:37

or like a five gram of fructose

21:39

in the fruit will not do anything

21:41

to me because it's inactivated. The first

21:43

five grams are inactivated in the good.

21:45

So you're not taking those blueberries away.

21:47

Blueberries are great. Berries

21:50

are great. I love

21:52

berries. You

21:54

know, if I was eating like four bananas, That's

21:57

going to raise my glucose up. That's not going to be good. If

21:59

I. The a lot of for

22:01

a while a bowl grades. And.

22:03

With a distraction to be good but in

22:05

like up a single fruit. Is

22:08

that could do anything except give you

22:11

good things Because got fiber. Pass.

22:13

Am chocolate are at your side

22:15

as I saw it as I

22:17

sit other side Athletes products I.

22:20

Had. The cat can is this away with a

22:22

blessing. You and the chocolate never node. Ah, that's

22:24

what I'm thinking. that chocolate too. So happy. Tadic

22:26

in. His. In fruit sleep. That's

22:29

on top of a few as I

22:31

ended up had ads also in chocolate

22:33

sand. We actually did a study where

22:35

we gave for does to people with

22:37

epic attitude and blocks from of the

22:39

fruits of sex. It's. Very is

22:41

to see. Nature was smart on now Yes!

22:43

So and so are you saying? like. To.

22:45

For it today. Yeah, I think you could

22:47

have of or at least one fruit with

22:50

each meal. Cool, That's my two to three

22:52

a day as Canada. it's another true today.

22:55

Don't. Eat for fruit in a to

22:57

put it in a blender and make a

22:59

big fruit juice because the injured in a

23:01

dec fifteen grams of fruit doser. Twenty.

23:03

Grams of fruit. us and we drink it fast

23:05

and that's where you get. i don't know. juice.

23:08

Yeah. You know I'm okay. would

23:10

like of for else. Or.

23:14

Like. A shot glass or that nobody

23:16

has who wants that less are having

23:18

a very arsenal are fun and but

23:20

the coins severe said that exactly. So.

23:22

A. Little bit of fruit juice. Is.

23:25

Gonna be okay. Okay so if you're at

23:27

a young age, Raster the fresh oranges that

23:29

we love and were in Florida. Ah,

23:33

Now. I just I never drink juice. Good

23:35

food. I just a little maybe a little if

23:37

I'm doing if I'm not having dry farm lines.

23:40

Then. I will do a little tequila

23:42

with a little line chess set. Lemon

23:44

and lime have no footsteps the I

23:46

as a bounce So okay so the

23:49

seed oil thing. Probably

23:51

not. probably just such as it is

23:53

fat assist problematic and I mean but

23:55

most people aren't. Sagging,

23:57

Down I would say most people who let's say. Like

24:00

we're at a conference. It's a Quito based

24:02

conference. I doubt they're doing seed oil. The

24:04

I. Just doubt it and then you

24:06

know, like I it's probably just problematic.

24:08

For the person is already. Inflamed and not

24:11

aware. And been

24:13

so. The fourth one is the fourth one. the

24:15

salt one another. For a close call, the

24:17

protein. But yes, I love this hypothesis.

24:19

And so this this hypothesis is that

24:21

you know a lot of the processed

24:24

foods were eating and a lot aren't

24:26

that many people are eating. You.

24:28

Know our protein low in

24:30

protein. And high in

24:32

fat and sugar and carbs.

24:35

And so they were having

24:37

a relative read. Reduced.

24:40

Protein. And. That

24:42

protein that our bodies need protein

24:44

Our bodies the protein from muscle.

24:46

They need proteins to run all

24:48

the chemistry of in a most

24:50

of the things that are body

24:52

that. Turn. Things on and

24:54

turn things off are made from proteins,

24:56

enzymes and all that so you need

24:58

to have and any protein is what

25:00

makes up muscle and how he is

25:02

super important we don't send or it

25:04

v s l a ser and you

25:06

need that nitrogen and so if you're

25:08

eating like protein and carbs and. And

25:11

ah, I'm I'm sorry. not protein,

25:13

suggesting carbs and fats and other

25:16

stuff. And you're not getting your

25:18

protein of the there's this

25:20

that the body responds. By.

25:23

Listening to you to eat. And.

25:25

So when the when there's some than of protein

25:28

you're going to eat more. And.

25:30

Ask you going to end up eating

25:32

more of the carbs and fab in

25:34

that's gonna try obesity at the same

25:36

and you know and it's a protein

25:38

problem that coffin in. A quid

25:40

somewhat be to like you look at

25:42

that data on ultra processed foods and

25:45

what they do to your metabolism and

25:47

help out like I'm a second tackling

25:49

holy Smoke sites. But n n it's

25:51

both sides. December one, the. Term effect

25:53

of foods lower. And

25:55

number two, you also get a

25:57

metabolic drop. so you would await need the

25:59

metabolic drop and then it also

26:01

makes you overeat. So your metabolism

26:03

drop and you overeat. Yeah,

26:06

it's a bad time. But

26:08

anyway, so the protein leverage

26:10

hypothesis basically says, you know,

26:13

there's this data that if you eat

26:15

a high protein meal that it can curb

26:17

appetite. It's true though. It's true. It's

26:19

kind of our diet. You

26:23

should tell me, have you ever gone to eat

26:25

somewhere? We were in Italy and decided we were

26:27

going to go have this Florentine steak and it was

26:29

44 ounces. Okay. We were piggies. But,

26:31

you know, so

26:34

we sit, we actually were like, we'll bring some

26:36

back to the hotel. Never happened. But

26:38

we were so full afterwards. We

26:41

literally went walking for hours because we're like, we

26:43

can't, we can't go back and lie down. But,

26:45

but at that point, like we probably

26:47

could have eaten an equal amount of pasta

26:49

as to that. And they would have rolled

26:51

through with the tiramisu and we would have

26:53

said, yes. Right. But like we

26:56

had the steak, if they rolled through inside another

26:58

steak on the house, we would have been like,

27:00

Oh no, we can't do it. No

27:02

protein. You just get full.

27:04

It does stimulate satiety. And

27:06

you know, one theory though is when

27:10

you eat a lot of protein, you

27:12

may be, you're eating less carbs. Right.

27:14

And so is the benefit from eating the

27:17

protein or is the benefit from not eating

27:19

the carbs? And that's where the

27:21

controversy. Or could it be both? I mean, you

27:23

have the thermic effect of, so you know what,

27:25

you're going to burn 20% more calories from

27:28

protein than from carbs. So it's carbs like five

27:30

to 10% thermic effect and protein 20

27:33

to 30. So let's say at least

27:35

20% more calories, just by switching out

27:37

some carbs for protein. You'll

27:39

still have a little instant response, but not

27:41

as high as the, the carb ones are,

27:44

but then you're more, I did a little

27:46

challenge. So I have an ongoing challenge that people

27:48

can join. That is my eat

27:50

protein first challenges. My next book by the

27:53

way. But all we have

27:55

people do, it's like one thing we

27:58

have them figure out how much protein they should eat. based

28:00

on their weight, and they divide that into

28:02

their three meals and eat that first. Yeah, that's a

28:04

good idea. You just eat it first, so you can't go. That's

28:06

a good idea. Because women especially go, oh, I just couldn't eat

28:08

all that. I go, because you already ate the muffin. No,

28:11

just eat it first. And what we found

28:14

is in just a week, people were like, I

28:16

wasn't hungry, I didn't have

28:18

cravings. I'm convinced a lot of our

28:20

food cravings are ultra-processed food, but also

28:22

that protein leverage hypothesis. Well, they do

28:24

the terrible thing. Most restaurants will serve

28:27

like a basket of bread. You

28:29

say no, don't you just say no to that? We

28:31

try, yes. We try. I

28:34

have a kid. Oh, you're

28:37

blaming it on your kid? Yeah, he always has

28:39

a girl. So, you know, I

28:41

have to say that, you know, if

28:43

you do get the bread,

28:45

and I mean, first off, a

28:48

low carb diet is by far the best

28:50

way to go. Intermittent

28:52

fasting's great too. And

28:56

a keto diet's great. But if you're

28:59

not on that, and your bread is

29:01

something that you can eat a little

29:03

bit of, don't eat it in

29:05

the beginning of a meal. Because it's

29:08

gonna be absorbed more rapidly. You're gonna

29:10

get a higher glucose, and

29:12

a higher insulin spike, and more

29:15

fructose. Well, and if you wait till the end,

29:17

and you ate that steak, maybe you won't eat it.

29:19

That's a good idea. There you go. I like the

29:21

idea of a basket of steak. Straight

29:23

up. Well, when

29:26

we order the appetizers, that's what we do.

29:28

We order some kind of like, you

29:30

know, protein thing. I'm gonna

29:32

eat that tonight when I go out to do

29:34

it. Excellent, do that. And then your, how's the

29:36

weightlifting been going? Oh, I have been doing it. Because

29:38

you made like a promise to me. Yes, yes, I

29:40

did. I

29:42

want to get the sun. I'm not good at it, but

29:45

I do go to the gym. I'm going to

29:47

the gym more, you know, I- Okay, what do

29:49

you do at the gym? Because just going to

29:51

the gym actually doesn't- Doesn't do it. I

29:55

go to the gym and walk around and look. You

29:57

like went to the gym? No. I

30:00

do it. They do the stationery

30:02

bike which is not weightlifting and

30:04

but I've been doing weight lifting

30:07

a little bit of upper body

30:09

and I do stretching to out

30:11

and as I get older and

30:13

legs. I've just had doctor and

30:15

Galpin here this morning and he

30:17

said the single most important things

30:19

for us. And terms of our

30:21

strength as we age is our

30:23

leg strength. You know? I believe

30:25

that. And I also believe that

30:28

stretching is really important just because.

30:30

As a physician ah when I when I

30:32

feel people who are really old one of

30:35

the. Things. That pounds.

30:37

And be the end. Is. Falling right

30:40

and the fall and break their ships.

30:43

And. It can be like the beginning of

30:45

the and I You know they get

30:47

blood clots surveys from complications. Are

30:49

they hit their head when they fall?

30:52

Farm. And so following is a

30:54

real serious issue and some of

30:56

the most important things. Just kind

30:58

of cute though. like strong arm

31:00

and around allowance test out Oxford

31:03

today that we we talk. well

31:05

what I do. Is

31:07

again up there in age style. But.

31:09

I do as a stand on one foot

31:11

into the. And. I put my

31:13

sock on the other foot. You know I'm

31:15

standing and good I do. These things are

31:18

so you know. To

31:20

improve to keep the balance. To.

31:23

Serve a person as you get older. Jesus

31:26

moved to try to. Put. Clothes

31:28

on city, You know it. Isn't.

31:30

Crazy that as we get old it's like

31:32

it's like everything's Oh, you should move from

31:34

the two story house to the once for

31:36

yes, It's like know you see the three start

31:38

out as be sex and then it's put your kitchen

31:40

all the way the top I think it helps. It's

31:42

like snow we have. did we have to continue. To

31:44

do more. And yes, We do less, We do less.

31:46

and we do less. Okay

31:49

so back over the desk as we gotta tie this whole.

31:51

Thing together now so. We have the it's bank

31:53

account. We have the chemistry lab. We have

31:55

the seed oil spring become a like. Shook

31:58

that one. Out. A bit weird. Protein

32:00

leverage hypothesis Good. It's good.

32:02

yeah definitely. I didn't like what my example

32:04

and it's funny because. A girlfriend just pinged mean

32:06

shows. hey we're going to have dinner New York shows

32:08

You wanna go. To. Eleven Madison Park

32:11

and have this hundred ninety five

32:13

dollar vision tasting menu and I'm

32:15

like can I bring a rose

32:17

to my predecessor Was it psycho?

32:19

Cause I always lead those situations

32:22

hungry. And bloated

32:24

so like if I can smuggle in some

32:26

protein I do like. okay never mind the

32:28

head of our six six but I do

32:30

like I or though to them when I

32:32

go there. Really beautiful but I'm hungry asked

32:34

the So definitely I believe in that one.

32:37

So so so of the way.

32:40

More reese recently we try to

32:42

show how these different guys can

32:45

actually. Connect. To

32:47

the each other. Through

32:49

a mile that's basically or a low

32:51

carb models so. What

32:54

we work our work is shown

32:56

his we gonna really big insight

32:58

is what causes obesity What weekly.

33:01

And it's really consistent and I

33:03

I I really think this is

33:05

the T. And that is.

33:08

You. Know. Or when when

33:10

Joslin and all these people said

33:12

you know that you that's obesity

33:14

is because he eat more calories

33:16

than than you use. The

33:19

whole concept is that. It

33:22

is about energy and I'm when

33:24

you eat we we use of

33:26

food to make energy. And.

33:28

The energy. As you know

33:31

to, there's. Really two types:

33:33

the energy that you're using. At.

33:36

The Moment which we call a T P.

33:39

Of because that's the name of

33:41

this complicated cassava. That's actually what

33:43

is. It's it's the energy

33:45

sources when we eat. We. Have

33:47

to have a T P to do everything.

33:49

Talk Walk. Jog. Sleep.

33:52

exercise every sound your leg

33:55

presses yes to be innocent

33:57

so easy peers like critical

33:59

and Then there's stored

34:01

energy, and stored energy is fat.

34:04

It also can be stored carbohydrates like

34:06

glycogen, but most of the energy

34:08

we start in our bodies is in fat.

34:11

We have fat and we have

34:14

the active energy or ATP. Just

34:16

think of it simply like that. The

34:19

way most nutrients work is

34:22

when you eat, if

34:25

you're hungry, your energy levels are starting to

34:28

fall, your ATP levels start to drift down.

34:31

Then when you eat, you restore

34:33

that energy. It all goes back

34:35

to the energy, the ATP. Then

34:37

when the ATP gets

34:39

pretty much to being full, the

34:41

leftover goes into the fat. The

34:44

fat gets the excess energy. Normally

34:48

we regulate weight. Animals

34:51

in the wild will regulate their weight tightly so

34:53

that they don't really gain weight. If the fat

34:55

goes up today, tomorrow, it's going

34:57

to burn that fat. You

35:00

try to keep it the weight. Everything

35:02

is about keeping the ATP levels high.

35:04

It's like keeping the gas tank full.

35:09

One nutrient does, and it's this nutrient

35:11

called fructose. It's in table sugar. It's

35:15

in sweets. It's

35:17

in high fructose corn syrup. Hence

35:20

the fructose. When you

35:22

eat fructose, it

35:24

actually actively lowers the

35:26

ATP. It's an active process. It

35:28

works on the energy

35:31

factories. It suppresses the

35:33

production of ATP

35:36

by those mitochondria. Here's

35:40

your ATP. You

35:42

want to bring it up to full. You

35:45

eat fructose and it drops it down

35:47

into the half. Suddenly, the alarm, the

35:49

sound goes up or the light goes

35:51

on your dashboard and it says, gas

35:55

low. It's

35:59

like an alarm. signal that says, hey, although

36:03

I need to eat more, I'm at risk.

36:06

But the way the fructose works

36:08

is it's suppressing the production. So

36:11

when you eat, the energy has

36:13

to go somewhere. And so the camp

36:15

we turn into ATP, it goes straight

36:17

into fat. So the fat goes

36:20

up, and the ATP goes down,

36:22

and eventually the ATP level will come up,

36:25

but at the expense that now you store it

36:27

all this extra fat. So it's a way to

36:29

make you gain weight. And

36:31

what was interesting is we were studying this, and

36:34

we realized that this is how animals in the

36:36

wild gain weight. This

36:39

is actually a biologic process.

36:41

It's like fructose

36:43

was meant to

36:46

lower ATP to

36:48

stimulate food intake, and even

36:51

insulin resistance is linked with this

36:53

low ATP because insulin

36:56

resistance is a survival mechanism. It's to

36:58

raise the glucose for the brain and

37:00

all these things, and

37:02

you drop your energy metabolism. That's

37:05

because you want to conserve energy

37:07

because you're at risk, and

37:10

your blood pressure goes up. This

37:12

is because we're worried that when you don't have enough

37:14

energy, you need to have a strong

37:16

circulation so that you can go out and look for

37:18

food. So it's like

37:21

a behavioral response, and it's driven

37:23

by this one sugar. The

37:26

sugar that for years was supposed to

37:28

be the healthy sweetener because

37:30

it didn't raise blood sugar. Right.

37:33

Interesting when you get exactly. So

37:36

when you get fructose, it doesn't stimulate

37:38

insulin immediately. It

37:40

just works through this ATP way. But

37:43

when it lowers the ATP, it

37:46

induces insulin resistance. So

37:49

insulin levels go up. Baseline

37:52

insulin levels go up. So you

37:55

end up in a high insulin state,

37:57

even though fructose doesn't stimulate insulin. Hugely.

38:01

It. Makes this isn't levels got chronically which

38:03

has the way worse if it that

38:05

way worse. So yeah, it was wonderful

38:07

as bend the Edmunds were. I'm sure

38:09

you renew his I know. I am so

38:11

get I'm here and then I couldn't get him in.

38:13

Well. You'd Arnett the I was laugh at

38:16

our yeah the guy fabulous he is bad

38:18

with the niceties and got this the serial

38:20

now that our yes he loves serial at

38:22

night or use. It

38:24

you know everybody has very wise and say

38:26

we all have our thing Here we are and

38:29

have a by five to turn him on the

38:31

Catalina Crimea example is buried him he's tried

38:33

that on answer did still oh my goodness

38:35

I will show you it when we're done It's

38:37

my vice I actually have a lizard fire and

38:39

into are out there. Ireland has effect of

38:41

there's no and or desert where no one

38:43

is perfect right? And but anyway.

38:46

But but the thing about fruit doses?

38:48

it makes the insulin levels go up.

38:51

And you can make it

38:53

does so originally. oh

38:55

soaked it was so depressing when

38:57

i'm actually did itself because originally

38:59

we were thinking for i was

39:01

just from the sure to reread

39:03

it was mainly how easy problem

39:05

as of long it as. It's

39:08

from a high fructose corn syrup is not

39:10

easy to the that's in the on solid

39:12

foods but it was kind of read in

39:14

under the. Bed. And

39:17

fortunately everybody who is it

39:19

is nutrition already knew this.

39:21

They knew that Potatoes and

39:24

rice and bread. Were. Sat

39:26

me. And I knew a

39:28

to his i was found that

39:30

a fire just cut out sugar

39:32

wasn't enough. And. So it

39:34

turned out, You know, So that it turns out

39:37

that pads. Stimuli. Fat. in

39:40

part by stimulating and slots just like

39:42

than answer. But. Also.

39:45

When. The blood glucose goes up some of

39:47

it is converted to fruit doesn't see

39:49

only way you can make group does

39:51

have some glucose and start since the

39:53

starchy foods. Will.

39:56

All make you. Can. Make.

39:58

For doesn't and then you're. energy drops and

40:00

it triggers the whole thing and causes

40:02

insulin resistance. And Ben

40:05

has made the case that insulin resistance

40:08

is at the key of everything. And

40:10

he wrote this beautiful book, I think,

40:12

why, why we're sick or something that

40:14

talks about insulin resistance.

40:17

And what's interesting is

40:20

fructose causes insulin resistance. And

40:23

you get that can happen from carbs.

40:25

So the carb insulin model says,

40:27

hey, carbs drive insulin, which drives

40:29

obesity, but carbs also

40:31

drive fructose, which drives insulin,

40:34

which causes it comes back.

40:36

It's just it's the same formula.

40:38

Carb insulin theory is correct. It's

40:41

just that it is all from

40:43

acute insulin effects and glucose. There's

40:45

also a fructose insulin resistance pathway.

40:48

So that's so what's really interesting is

40:50

a fructose. It explains

40:52

the energy balance because fructose makes you

40:54

hungry. So you eat more and

40:57

fructose drops your energy. So you

40:59

exercise less. Yeah. So now you're

41:02

moving less. Yeah, you're moving more,

41:04

eating more. And you're

41:06

activating this insulin pathway. So

41:09

it actually combines the two

41:12

the two theories. But the energy

41:14

balance is really only driving weight,

41:17

but the carb pathway

41:19

is driving disease. Yeah. And I think

41:21

that that is that is such a key thing

41:24

because my mission is

41:26

to get people to stop trying to

41:28

stop focusing on losing weight and

41:31

instead focus on improving what that weight is made up of.

41:34

And I had a great mentor early on. She goes, you

41:36

know, you don't lose weight to

41:38

get healthy. You get healthy to lose weight. And so I

41:40

realized this really, you get metabolically healthy to

41:42

improve your body composition. And if we could

41:44

stop like the fact that you go to

41:46

a doctor's office today and you still get on

41:48

a scale instead of getting on a bio impedance. Scale

41:51

or doing it is so stupid. I

41:53

can't even believe it is still

41:55

happening. I'll tell you a story. When

41:57

I was in Gainesville and we started doing.

42:00

this, we had a, I consulted

42:03

with a young lady who was

42:05

a bodybuilder. And she had a,

42:07

you know, beautiful shape, and she'd

42:10

get up and do this professionally

42:12

and lift weights. But

42:15

she ate very little, and

42:17

she ate, she liked sugar. And

42:20

she was eating kind of a high

42:22

sugar, low calorie diet. And

42:24

she got fatty liver. Wow. And bad,

42:26

where she actually started getting ascites,

42:29

you know, water. Wow. And

42:31

she also got hypertension. And

42:34

she got insulin resistant. So

42:36

even though she was, had

42:39

very little external fat, you

42:42

know, she looked like a pro. She

42:44

looked like, she looked like she was

42:46

on a carnivore diet. You would think like,

42:48

inside she was a mess. This, this is

42:51

the disturbing thing with that. And it, because,

42:55

you know, that

42:57

whole statement, you can't out exercise a bad diet.

42:59

And it's kind of argued back and forth, because they're

43:01

like, Oh yeah, when you exercise more, you can get away

43:03

with those things. But you just showed it. No, you can't.

43:06

So what is really interesting here is,

43:08

and I think this is important.

43:10

And I actually think this is the real

43:12

big message, because the message really is that

43:14

we have to look at what our weight's made up of. And

43:17

is the diet we're doing improving our health?

43:19

Because who like, so you look good and

43:22

inside your train wreck, that doesn't

43:24

make any sense. You know,

43:26

that for a long, as a physician, that for

43:28

a long time, we were sort of told

43:30

that, you know, obesity

43:33

was a disease, and that

43:35

it was associated with, you

43:38

know, insulin resistance and all these things. But

43:41

you can separate weight gain from

43:45

metabolic disorders. And you can

43:47

be thin with bad metabolic

43:49

disease, or you can be

43:51

overweight and be relatively healthy.

43:54

And also depends where your fat's located, right? If you have

43:56

like 25% body fat, but a lot of visceral. of

44:00

post-tissue, it's very different than having barely

44:02

any. Absolutely true. And

44:06

so anyway, so yes, so that is

44:08

a big thing. The CARB insulin pathway

44:11

clearly is driving metabolic

44:13

disease and the

44:15

energy balance pathway does not.

44:17

Well, I think this really shows the

44:20

story that the story really isn't, you

44:23

know, it's not just that you're looking to lose weight,

44:25

right? Absolutely. Okay, so

44:27

then we move past that. The other one

44:29

that I would love you to talk about

44:31

is how alcohol plays into this. Oh,

44:33

sure. And I want you to give us

44:35

all good news. So a long time ago,

44:38

you know, there

44:42

was, well, maybe 15 years ago, there was

44:44

a, you know, a paper in the New

44:47

England Journal that said that

44:49

red wine was

44:51

healthy and could reduce heart attacks.

44:55

And there were good things in red wine

44:57

that were, you know, and that we

44:59

should not worry. And kind of the curve showed

45:01

that one

45:03

glass of wine was actually superior

45:05

to zero. No, this made my

45:08

heart sing. Exactly. Two glasses were

45:10

kind of equal to zero. And

45:13

so when that came out, I, you know,

45:15

I was early in my

45:18

nutrition research, but I've always viewed

45:21

that as, hey, you know, a glass

45:24

of wine is fine. It's different from

45:26

beer. Beer tends

45:29

to raise uric acid more and

45:31

activate and actually the purines and

45:34

the brewers' Eastern beer is

45:36

not as good. And even though

45:39

my roommates in college and, you

45:41

know, I always had roommates

45:43

who liked to brew beer

45:45

and make beer, and

45:47

we would go to these beautiful places

45:50

where they would have home brews. But

45:53

beer is actually, has some

45:56

fattening and metabolic effects and the

45:58

beer belly is real. And

46:00

it's a social fatty liver in

46:02

high triglycerides and you know, so.

46:05

Bears. Out beers, beers out. If you go

46:08

drink they're just snowed. An occasional beer with

46:10

after you. Exercise a

46:12

lot and you know that, Done all

46:14

that, you know, an occasional maybe, but

46:16

it's. And

46:19

hard liquor and can also raise

46:21

your gas is pretty strongly as

46:23

off and mix with sugar bright

46:26

and all these are and so

46:28

and frankly and all call islam

46:30

is most part time and issue

46:33

drinking hard liquor is huge him.

46:36

During. A lot more during a lot more

46:38

so wine. Soon to be the perfect. Perfect

46:42

drink, the perfect alcohol. Ah, and

46:44

a glass of wine. Often

46:47

tastes great with them

46:49

right now. Now. Com

46:51

some news. That's not how.

46:54

I. Never have also ever mans podcast

46:56

darn it as soon as I

46:58

during the go out on a

47:00

terribly good news but. We'll let

47:02

me just tell you it's so that you know.

47:05

And that is that. Are when

47:07

you drink alcohol. You.

47:09

Actually use Emulate a

47:12

production of Us. Now.

47:15

Interest: Stanley. Are

47:18

the production of fruit juice requires

47:20

lucas to be around. So.

47:23

If you drink alcohol. And

47:25

you're on a low carb diet you may

47:28

that as we all realize that for does.

47:31

Ah, And I hadn't thought about, but that's

47:33

probably true for stealth fighter for other. Because

47:36

they are called only makes the

47:38

carbs if you. If there's

47:40

a fair amount of glucose rock. Okay well

47:43

that works with my steak and salary and

47:45

federalize gonna work well. fact the like if

47:47

you if you were. At. A

47:49

bar, And you

47:52

ordered a wine and

47:54

they bring press. Hearts.

48:00

Arms or. Will. Be turned

48:02

into freaked other that in low ballers little bit

48:04

death. Yeah if you ever been

48:06

to prime when twelve in Miami. Know

48:08

but it I would likely to have. You really

48:10

like to go because at the bar Now this

48:12

I pretend. Emigre be they don't do anymore. but. The

48:15

this place. You'd sit at the bar

48:18

and they'd have these huge glasses of

48:20

of thick sliced. Bake it Saudi

48:22

and that's what they gave you. a

48:24

new sat down tomorrow might have. This

48:27

is my place. A perfect but for

48:29

surely well getting back. So the with

48:31

Vienna so alcohol can make for those.

48:34

Are group has the animals

48:36

on alcohol. And. We

48:39

found that the animals would get

48:41

fatty liver and in a one

48:43

of the biggest problems with alcohol.

48:46

in also alcohol and accesses is

48:48

really bad alcoholism. To

48:50

terrible condition and some people

48:53

get liver failure from alcohol.

48:55

So. Though are you know how I

48:58

like wind? and I. Will.

49:00

Easily have a glass or to. I

49:03

am afraid of committed an

49:05

alcoholic and I'm I'm sad

49:07

when I see alcoholic because

49:09

of excessive alcohol can really

49:11

lead to bad. Liver

49:13

disease and liver failure and

49:16

I'm. In So when

49:18

we gave alcohol to animals and

49:20

they made crypto some fruit does

49:22

causes fatty liver wow they got

49:24

over time they started getting liver

49:27

disease and likewise if I gave

49:29

alcohol with sugar the liver disease

49:31

was much worse and I did

49:33

this. I should argue that this

49:35

was stars should mention this was

49:37

where and would Mcgowan aspa He

49:39

is actually the leader of the

49:41

stuff. And then

49:43

of we blocked for dogs. They.

49:47

Wouldn't get the liver disease so we

49:49

actually won't leave their little thing litter

49:51

and take with heard that well below

49:54

yellow line was yet and cellulose my.

49:57

Oh. I don't know yet. They could. But.

50:00

You know people are trying to develop

50:03

inhibitors of Frutos. But. I'm.

50:06

What I'm pretty sure others that

50:08

you know there's a sliver disease

50:10

that occurs with alcohol is. Is.

50:13

Particularly worse if you're drinking alcohol

50:15

and eating a lot of carbs

50:17

and I'm. So. I would

50:19

really suggest if you do drink alcohol, try not

50:21

to eat a lot of times with a duck.

50:24

Try not to drink with. Sugar

50:26

or it's sugary. drinks. Cause.

50:29

Of that all. Costs.

50:31

Increase the risk your liver disease. Now

50:33

the other side is that when we

50:36

blocked for doesn't the mouse. The.

50:38

Animal still like alcohol. This.

50:41

Is good. But. They don't drink

50:43

as much about through drinking down

50:45

by fifty plow thirty percent. So

50:47

the National Institute of Health has

50:49

funded be to do research on

50:51

this because it looks like if

50:53

you block sugar. You. Can

50:55

Max You know you might be

50:57

able block alcoholism and I saw

50:59

the Wow armor. Yesterday. Presented

51:02

at this metabolic tell summer. That.

51:05

Of you know that Cheeto

51:07

diet Smythe actually called with

51:09

alcoholism. And are you know

51:11

to a guy would reduce the fruit

51:13

does production from alcohol. And

51:16

of and so maybe. You

51:19

know, if you're on a low carb

51:21

diet air air, you know alcohol will

51:23

probably be a little safer. And.

51:26

Down. The You

51:28

know? Ah, Have you glass?

51:30

Why deny? Nice. And it's

51:32

try Farm happen. So there you go. You

51:34

know that try Farm don't. You know it's

51:36

not even not know this I should Oh my

51:38

god I will get really fucked up with them

51:40

and were. So. Dry Farm. why

51:43

I do is spend too much time

51:45

in the laboratory abyss. This is important.

51:47

My Catalina crunch and dry for wines

51:49

and these are like like changing lanes

51:52

seven introducing cigarettes. So Dry Farm winds.

51:54

Is that the sky? Todd

51:57

White was a quito guy

51:59

and. He couldn't drink wine because it would throw

52:01

him out of ketosis Then someone gave

52:03

him some European wines and he knows it didn't throw him

52:06

out of ketosis So then he wanted to know why so

52:08

he then he went and

52:10

lab tests them and he discovered That

52:13

the residual sugars were really low

52:15

that the alcohol content was lower

52:17

that they were so different So

52:19

he created a company called dry

52:21

farm wine. They go all over Europe. It's

52:23

think of the crappy job He has he

52:25

has to go around Europe sourcing these wines

52:29

So I'm like Todd But

52:31

he it is an amazing company.

52:33

In fact, they have they

52:35

sponsor here. They also sponsor mindshare They bring

52:37

all the wine to mind sure even sponsored

52:40

our wedding so But

52:43

it's once you drink this you don't you

52:45

don't feel rotten drinking it Yeah,

52:48

you buy it anywhere you you become a

52:50

member of their club But

52:52

I will connect you with you know, will

52:55

you because you really need to know this

52:57

because I'm really interesting Like wine and I

52:59

do drink a glass usually almost every well

53:01

three or four times a week Yeah,

53:04

we used to be drinking a glass

53:06

We drank two glasses at a night every

53:08

night and then the Urban Labs podcast came out.

53:10

I'm like, oh Darn it

53:12

and then we decided, you know, we don't need

53:14

to do it every night So we kind

53:16

of failed on that but still

53:18

to me if you're going out to a

53:21

nice dinner Like and we'll just

53:23

bring it right. I'm gonna have a glass of

53:25

red wine. I know you're inspired now With

53:28

a little protein there. I would love to

53:30

well, you know just think about it. You're eating your

53:32

protein first Yeah, maybe having some non-surgity

53:34

vegetables. You have a glass of wine. Here's where's

53:36

the problem. You wanted the problem Yeah, yeah, you

53:38

want there. We solved it. I love

53:40

science in action. Yeah. Yeah I thought

53:42

about the fact that alcohol would be safe

53:44

safe for a in a keto diet, but

53:46

it should be well I wonder to

53:49

like I would love you to talk just a little

53:51

bit because I know you have to go out to

53:53

dinner But I'm about alulos. Oh,

53:55

yes, so So

53:57

I you know, I've been studying in at

53:59

the University The received word. Twenty.

54:02

More than twenty years and doing

54:04

research. And. I decided go half

54:06

time last summer. And I

54:08

was approached. Ah, By a

54:10

company called Art Sugar and Steve

54:13

Haley an. Arm. And

54:15

in a kangaroo he said hey, you know we

54:17

have a. Low. Calorie sugar that

54:19

looks just like for does he want

54:21

to look at and you're thinking ryan

54:23

have heard that the heard of senate

54:25

side they gave yeah outfit doses and

54:27

so good but that he says it

54:30

does he know it it it makes

54:32

things better not worse. So. I.

54:34

Started reading about and I go My

54:36

gosh, this thing looks like group does

54:38

but it's that one of the hydroxy

54:40

group decode down and set of up

54:43

and is in. I found that it

54:45

wasn't activated by this pathway that causes

54:47

the energy to drop. Side.

54:49

Or such not causing the energy. Drop by

54:51

lox like. Maybe

54:53

it's a safe sugar and I've been reading

54:56

about it. I thought, well, you know And

54:58

then I saw a surge send me papers

55:00

that suggested that I might actually have a

55:02

metabolic The Banner. And. A low

55:05

calorie sugar with a metabolic? Better than yeah?

55:07

Come on time. I've. Ever

55:09

seen that fits the unicorn sour

55:11

apple was in August zero after

55:13

reviewing the side said yes I

55:15

would like to join your company.

55:17

Ah as the scientific officer. With.

55:20

The goal of trying to figure this out in

55:22

a how does this work? What. Is.

55:24

It really beneficial. I know it

55:27

doesn't look back. At. All

55:29

the paper suggests it's benefits on since

55:31

then. We. Have to. We're

55:34

finding centered shown in people.

55:37

Ah, and it's very, very evident

55:39

what is it does lower? Glucose.

55:42

Levels, especially after a meal

55:44

doesn't lord will cost much

55:46

as take you have to.

55:50

Mail and blocks Maclin comes from? Yeah,

55:52

which is here so you're going. The

55:54

blood sugar response to me although all

55:56

the things everyone's been doing had their

55:58

blood sugar in our desks. it and

56:00

you need to take it because when I

56:02

heard that first of all I've been trying to crack the code

56:04

of okay how much of this before the

56:07

meal during the meal after the meal

56:09

for the glucose part you can take it any time

56:11

during the meal but obviously if you gave it in

56:13

the beginning of the meal it would be a little

56:15

better and the amount it

56:18

can be 10 grams or less okay

56:20

there are papers showing 5 grams which

56:22

is very little aloe is like

56:24

half a bar but

56:26

a 10-gram bar for sure you'll get

56:29

a big effect and you know you

56:31

may want to try it out and

56:33

just check it I've got I'm gonna

56:35

test it yeah you know you'll be

56:37

amazed and then the second is

56:40

that it stimulates GLIP-1 yeah this is

56:42

beyond exciting for a lot of different

56:44

reasons like to have because GLP-1 agonists

56:47

are the big rage now and and

56:50

I was lucky because

56:52

last year I was in a

56:54

lecture at integrative healthcare symposium with

56:57

dr. Bill Seats who is a big

57:00

he's been using peptides for years and

57:02

he was telling us everything beyond first he

57:04

was talking weight loss but then after the

57:07

talk ended he started talking about the neurocognitive

57:09

effects the cardiovascular effects like you start to

57:11

look at GLP-1 I think we're gonna be

57:13

blown away at what it really does so

57:16

when we look at this you

57:18

know it's clearly stimulating GLIP-1 we just

57:20

did some experiments this week where we

57:22

you know confirmed it how

57:24

are it so how do you find out it

57:26

relates GLP-1 about 10 times more than 5 to 10

57:28

times more than glucose

57:32

it's a real potent stimulus and

57:35

and and what GLP-1 so all

57:37

the things that are good about

57:39

GLP-1 you know aloe

57:41

loss we're hoping it's gonna show and

57:44

it's like lowering glucose there's some evidence

57:46

that my improved exercise these are all

57:48

antibodies the only thing that's really convincing

57:51

that's absolutely convincing is the glucose effect

57:53

but there are studies showing that it

57:55

can lower prevent weight gain I mean

57:57

Ben just did one that he presented

57:59

these These results as the sweet.

58:02

A. Panic and black weight gain in

58:04

an animal from a high fat face

58:06

sugar diet. Saw. It and you will

58:08

have to have a high sugar die because you can just. Alia

58:11

Los is the most amazing sweetener. Be

58:13

has all the other sweeteners. Either try

58:15

to be ever. Tried side at all. I

58:18

think so. The most good know it's the

58:20

most that like. Be worth of

58:22

the stomach. Like. The Worst. Gas and

58:24

I mean acts not only bad gas, but

58:26

like. Room clearing bad for

58:29

gas as Alex Howes good for teeth It's

58:31

yeah stranger is little a little bit parties

58:33

but like but it easier when I target

58:35

circuit actually yeah that I was so busy.

58:38

The bathroom a little the right. It's like

58:40

all of our freeways tools. Gas and cramp.

58:42

so you either get that before they have

58:44

a weird. There's. Something to show

58:46

though it's to aftertaste so I was. I've

58:48

always been playing around. with combining like or it's are

58:51

tall with monk for it was still trying to get rid.

58:53

Of that just hit the taste. But then

58:55

the idea that this one. Has.

58:57

No, we're taste. And actually

58:59

as therapeutic cats fatigue and you can

59:01

cook with it like you're like. Come.

59:04

On I'm a professor who's you

59:06

know, always been loyal to the

59:08

university in. Spend. All my

59:10

time doing research in an age

59:13

grandson. But. When I saw this

59:15

are to send in on this is

59:17

Sandy. None of this isn't a slow

59:19

college students and. Often helps

59:22

Bolland. Place for us.

59:24

It's also because I spent my

59:26

career trying to figure out how

59:28

to block fruit have suffered so

59:30

race or was very consistent were

59:32

greeted joined the company. And

59:34

denotes my goal is to learn more

59:36

about the sugar and to do or

59:39

trials clinical trials. I'm a Clinical Trial

59:41

Di Vita. Two.

59:43

Thousand two hundred people on show that it

59:45

really is beneficial and when's the best time

59:47

to take it? And ah you know and

59:49

I've been likes his all that firing questions

59:51

they've sent me all the stuff they have

59:53

I'm like okay then and now effect Oh

59:55

god Why that a gift for my phone.

59:59

Or much. What if it? It but I

1:00:01

think you know just for anyone to

1:00:03

the I sense a get. Us all

1:00:05

the time. Like what can I put my

1:00:08

coffee and who would go next as a

1:00:10

claim? that? sure it is. So I've been

1:00:12

testing taking it. Either before

1:00:14

or after meal. And truthfully, his

1:00:16

sister cities I. Can feel immediate, area

1:00:18

I can I'm like, okay, wow, well,

1:00:20

you know, so it's pretty crazy death

1:00:22

the first time we tried it my

1:00:24

wife and. Are talent. Couple

1:00:28

bars are. You. Know

1:00:30

right after election. That.

1:00:32

Night we did have dinner every those

1:00:34

like we were full. There are bars.

1:00:36

Are these spells stealth? This was a

1:00:39

little truck. The those little bars. Hundred

1:00:41

metres Idiotic? Yeah, they're quite good. Dark

1:00:43

chocolate al yellows and you are not

1:00:46

hungry whatsoever. It's. Pretty incredible. Are

1:00:48

I know you need to go to dinner?

1:00:50

Yes, this has been incredible. You have

1:00:52

Vom. We will. Do.

1:00:54

A little thing and printing of what stuff

1:00:57

we won a link to your your book

1:00:59

nature why I am the waters lose you

1:01:01

That anything else that you want to share

1:01:03

with everybody to one on issuances to be

1:01:05

set our Buchanan one or a bomb and

1:01:07

more relevant than ever. Yeah like great stuff

1:01:10

Really Yes we will link to that A

1:01:12

Doctor John Seven of Remember to get some

1:01:14

of this. Know you? taking that

1:01:16

one with the of undertaker live? You cannot.

1:01:18

Why? World. For s that's that's antacid.

1:01:21

A little present there and. Fishery

1:01:27

Joni Nice new tools, tips and

1:01:30

techniques. You can incorporate into. Everyday was

1:01:32

A to ensure you live in

1:01:34

today, into each that you built

1:01:36

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1:02:01

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1:02:03

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1:02:05

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1:02:08

Only He should not rely on this

1:02:10

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1:02:12

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1:02:14

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1:02:16

questions about your health. You should always

1:02:19

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1:02:21

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1:02:23

Do Not disregard avoid or delay a painting,

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