Dr. Jason Hawrelak is a probiotic researcher, educator, clinician, and Head of Research at ProbioticAdvisor.
Do I have a show for you this week! Fan of exploring the gut microbiome? Did you know our nose, skin, mouth and vagina all have microbiomes too and healthy or not, they have impacts on our overall health? We look at not only gut but vaginal and nasal microbiomes as well this week with Australia’s foremost probiotic expert Dr Jason Hawrelak - back for a second time and boy were there some mind blowing facts shared in this week’s show. Dr Hawrelak did his Honours (First Class) and PhD degrees in the areas of the gastrointestinal microbiota, irritable bowel syndrome, and the clinical applications of pre- and probiotics. He has written extensively in the medical literature on these topics – including 16 textbook chapters – and his research has been cited over 900 times. Suffice it to say, this week’s show is a good one for the microbiome nerds among us. I hope you enjoy this week’s show and as always, you can find this week’s podcast sponsor offer and show notes over at lowtoxlife.com/podcast Enjoy! 
The gut continues to be a hot topic, thus one I welcome putting on a show about when I find the kind of guest that can take things to the next level of our understanding of our inner garden. So, this week my guest is Dr Jason Hawrelak. We go deep into the microbiota, the latest gut research, gut brain connection, IBS, fodmap restriction and how to bring back the fibre minus the symptoms, constipation, Keto and certain strains that are winning in the research when it comes to depression, anxiety and more!  Dr Hawrelak is Head of Research at ProbioticAdvisor.com. His passion for gastrointestinal health, the GIT microbiota, and probiotics was ignited during the final year of his undergraduate training. Subsequently, Dr Hawrelak did his Honours (First Class) and PhD degrees in the areas of the gastrointestinal microbiota, irritable bowel syndrome, and the clinical applications of pre- and probiotics. He has written extensively in the medical literature on these topics – including 16 textbook chapters – and his research has been cited over 900 times. I hope you enjoy this week’s show and as always, you can find this week’s podcast sponsor offer and show notes over at lowtoxlife.com/podcast Enjoy!
Dr. Jason Hawrelak joins me to discuss the role of microbes in our gastrointestinal system and what we can do to look after them. Our understanding about microbes is rapidly evolving, we are now able to apply these new learnings to improve a wide variety of health outcomes. Jason is a naturopathic physician who has done both honours and his PhD in the areas of intestinal dysfunction, microbiome manipulation and the clinical applications of both pre and probiotics. Jason specialises in the treatment of both acute and chronic gastrointestinal disorders, such as irritable bowel syndrome and irritable bowel diseases. Selected Links from Episode Dr. Jason Hawrelak website Unstress episode with Dr. Robert Rountree on gut health Bristol Stool Chart Download the PDF transcription   Dr. Ron Ehrlich: Hello and welcome to “Unstress”. I'm Dr. Ron Ehrlich. Our relationship with bacteria is changing. Well, our knowledge and understanding is anyway. It's been an adversarial relationship for over a hundred years and with the advent of antibiotics and antimicrobials, along with products that promise to make our surfaces and bodies 99.9 percent antimicrobial and clean. As well as you'll hear of a very symptom-based approach to common health issues. All of those things well they're kind of changing. We're learning that the majority of microbes are actually our friends and we need to learn more about them and how to look after them. My guest today is Dr. Jason Hawrelak. Jason is a naturopathic physician who has done both his honours and his PhD degrees in the area of intestinal dysfunction, microbiome manipulation and the clinical applications of pre and probiotics. He's also a herbalist. He has taught health professionals at both the undergraduate and postgraduate level for the past 16 years and is currently the senior lecturer and coordinator of the evidence-based complementary medicine program at the University of Tasmania's School of Medicine. Jason has written extensively in textbooks and journals and specialises in the treatment of gastrointestinal disorders both acute and chronic such as irritable bowel syndrome and irritable bowel diseases like ulcerative colitis and Crohn's disease and much, much more. I hope you enjoyed this conversation I had with Dr. Jason Hawrelak. Download the PDF transcription Welcome to the show Jason. Dr. Jason Hawrelak: Hey, thanks Ron thanks for the invitation to come in and chat. Dr. Ron Ehrlich: Now Jason I'm picking up a very, very slight accent there and I know you're based in Tasmania and you've done your PhD you've done a huge amount of writing. I wonder if you might just share with our listener a little bit of your journey to this point. Dr. Jason Hawrelak: Yeah, sure I sometimes forget I have an accent because I sound normal to me, but I did grow up in Canada at a city called Calgary which is near the Rocky Mountains. So, I grew up with that as my sort of local background and thinking that beautiful turquoise coloured rivers were the norm everywhere, little did I know that they are actually quite the exception and I was one of those aspiring backpackers who was intent to travel around the world but didn't get that far, I got to Fiji, New Zealand and Australia and fell in love with Australia and subsequently never left and that was back in 1992. So, I'm somewhat surprised, I've been in Australia longer than I was ever in Canada, but I still have I think a Canadian accent strangely enough. Dr. Ron Ehrlich: It's very soft, it's very soft I was being picky. Dr. Jason Hawrelak: That's all right. It's good it's still there, I met someone from Canada today and it seemed I was Australian right off that. Yeah, but I essentially went to Northern New South Wales where I arrived few days into Australia and lived up there and was lucky enough to study up there so that's where I did my original undergrad training, which was a Bachelor of naturopathy up at the Southern Cr...
In today’s episode, Dr Nirala Jacobi welcomes back Dr Jason Hawrelak, to talk about Microbiome Restoration. Dr Hawrelak is a researcher, educator, naturopath, and nutritionist with over 16 years of clinical experience.  He also practices at Gould’s Natural Medicine - a 135-year-old natural medicine apothecary and clinic in Hobart, Tasmania, Australia. Dr Hawrelak completed his PhD examining the capacity of probiotics, prebiotics, and herbal medicines to modify the gastrointestinal tract microbiota.  He is the senior lecturer in Complementary and Alternative Medicines at the University of Tasmania’s School of Medicine where he coordinates the evidence-based complementary medicines programs.  Dr Hawrelak also teaches the gastrointestinal imbalances unit, within the Masters of Science and Human Nutrition, and Functional Medicine Program at the University of Western States, in Portland, Oregon.   Topics discussed include: The SIBO Doctor courses Microbiome Restoration - coming soon Regrowing vs killing in the microbiome. Colonic collateral when we are dealing with SIBO, and the necessity to restore the colonic ecosystem as part of the SIBO treatment. How do we learn to interpret the DNA readings and PCR reports? The SIBO Doctor Microbiome Restoration course A discussion of the modules offered in the Microbiome Restoration course Module 1 - Testing The difference between different labs Culturing vs DNA techniques Assessment, Interpretation, and Diagnosis Module 2 - Beneficial Bacteria, including Akkermansia Faecalibacterium prausnitzii Butyrate-producing microbes Hydrogen sulfide gas producers Module 3 - Pathobionts The good, the bad, the ugly Hydrogen sulfide producers Methanobrevibacter smithii coli Bacteroides Triple antibiotic therapy (for conditions such as H. Pylori and Blastocystis Hominis) and the impact on the colonic ecosystem balance of symbionts and pathobionts. Dietary changes vs probiotic supplements to elicit change in the gut microbiome. The complications between advising prebiotic nutrition for optimising microbiome restoration, whilst clients are on therapeutic diets such as the Low FODMAP diet - how to reconcile? Hydrogen sulfide breath testing - coming soon. High-fat content diets in SIBO, and how this can eventually feed hydrogen sulfide producing bacteria. Symptoms such as food reactivity and visceral sensitivity as a consequence of dietary choices in SIBO treatment, in regards to hydrogen sulfide producing bacterial blooms. The therapeutic benefits of Soy Isoflavones in relation to Methane and Hydrogen Sulfide producing SIBO patients. Equol producers - patients who have bacteria that convert soy isoflavones into the bioactive component, Equol. Adlercreutzia levels in people who eat soy products as a long-term dietary choice. Is there a connection between histamine intolerance, salicylate intolerance, and oxalate intolerance and microbiome disturbances? Post SIBO treatment food sensitivities - the colonic microflora patterns to observe. Hydrogen sulfide gas and how it causes visceral sensitivity, gut leakiness, and inflammation in the nerves. Dietary changes with people with sensitivities - a reiteration of start low, go slow. Is there any clinical significance to oxalobacter formigenes being elevated? What is the dietary impact of the extinction of oxalobacter formigenes? Testing levels of Proteobacteria to uncover the innate endotoxin load (proteobacteria - gram-negative bacteria that secrete proinflammatory endotoxins). The systemic repercussions of endotoxemia - leaky blood-brain barrier, gut damage, insulin sensitivity impacts, systemic inflammation, Alzheimer's, anxiety and depression links. Endotoxin (also known as Lipopolysaccharides - LPS) absorption and high-fat How do different Phyla respond to different diets? Potential outcomes of the ketogenic diet depending on the dietary nuances - decreased microflora diversity, increased hydrogen sulfide gas-producing bacteria, and increased numbers of proteobacteria. Akkermansia and constipation - why are these often seen together? Gut inflammation and mucus tend to increase Akkermansia if it is there - it is a mucin eater. Gut markers of inflammation, such as calprotectin. The vocabulary to use around probiotics - not re-seeding, but rather restoring. The importance of lactic and acetic acid production adjusting the pH of our microbiome to be hospitable to beneficial bacteria. D-Lactate considerations. Biogaia effectively reducing methane production, and also being used alongside proton pump inhibitors (PPIs) to prevent the development of SIBO. PPIs - when to use and when not to - listen to Dr Steven Sandberg-Lewis’ podcast on SIBO and Functional GIT Exam Skills. Plantarum LP8 is being used in research to decrease Desulfovibrio, increase butyrate and bifidobacterium - can we use other strains of L. Plantarum to elicit similar changes? Plantarum strains to use in gut rehabilitation. Reuterin production. Dr Hawrelak’s antimicrobial and dietary recommendations for treating Desulfovibrio.   Resources Dr Hawrelak Probiotic Advisor Gould’s Natural Medicine   The SIBO Doctor Microbiome Restoration Course with Dr Jason Hawrelak [Opens 13 June] Sign Up for the Course and Live Q & A with Dr Hawrelak The SIBO Conference New Orleans - speakers mentioned Dr Richard McCallum Dr Matthew Bohm   Labs mentioned Ubiome - microbiome DNA testing Genova   Dr Satish Rao SIBO and comorbid SIFO D-Lactic Acidosis researcher   Dr Steven Sandberg-Lewis Dr Steven Sandberg-Lewis’ podcast on SIBO and Functional GIT Exam Skills  
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Creator Details

Episode Count
6
Podcast Count
5
Total Airtime
6 hours, 40 minutes
PCID
Podchaser Creator ID logo 900709