Emily Greenstein, APRN, CNP, CWON-AP, FACCSW and Ralph J. Napolitano, Jr. DPM, CWSP, FACFAS discuss the importance of recognizing the economic and patient quality of life impact of periwound skin damage, and explore some of the main factors that affect periwound integrity. Then they'll examine the role of novel silicone-acrylic drape with negative pressure wound therapy in patients with periwound skin breakdown.