In the second episode of Season 2, Alexa Cohn and Jonathan Sogin take us through two new papers detailing a novel operon structure and antibiotic resistance mechanism. For molecular and non-molecular biologists alike, this episode is sure to bring out the science in Food Science. But, it’s not all about science - Alexa tries painting and Jonathan attempts karate; they definitely won’t be quitting their day jobs anytime soon. 


Papers:

Saenz-Lahoya, S., Bitarte, N., Garcia, B., Burgui, S., Vergara-Irigaray, M, Valle, J., Solano, C., Toledo-Arana, A., & Lasa, I (2019). Noncontiguous operon is a genetic organization for coordinating bacterial gene expression. Proceedings of the National Academy of Sciences, 116(5): 1733-1738. https://doi.org/10.1073/pnas.1812746116

Duval, M., Dar, D., Carvalho, F., Rocha, E.P.C., Sorek, R., & Cossart, P. (2018). HflXr, a homolog of a ribosome-splitting factor, mediates antibiotic resistance. Proceedings of the National Academy of Sciences, 115(52): 13359-13364. https://doi.org/10.1073/pnas.1810555115

Dar, D., Shamir, M., Mellin, J.R., Koutero, M., Stern-Ginossar, N., Cossart, P., & Sorek, R. (2016). Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria. Science, 352(6282). DOI: 10.1126/science.aad9822