Episode Transcript
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0:03
Have you ever wanted to freeze time
0:08
to preserve life? For
0:12
the past 12 or so years, the
0:14
option of freezing eggs has been popular
0:16
for women who may want kids but
0:18
don't want them right now. If the
0:20
perennial question is, can women have it
0:23
all, could the
0:25
answer be egg freezing? Some
0:27
companies even started to offer to pay for
0:29
the procedure, on average about $11,000 per
0:32
cycle, as a perk of employment. With
0:34
the great resignation and full swing, it's
0:36
become hard for companies to hang on
0:38
to their people. And so
0:40
now we're seeing egg freezing, IVF
0:43
and others emerging as
0:45
a whole new category of benefits up for grabs.
0:47
And now, a dozen years on, we're getting
0:50
the data on how well this process has
0:52
been working for women and for families, and
0:54
those outcomes are coming up on Today Explained.
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cable provider and kindly demand today
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explained. My
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name is Anna North.
2:34
I'm a senior correspondent for vox.com, where
2:37
I cover American family life, child care,
2:39
education, and a whole lot of other
2:41
things. You recently wrote
2:44
a piece for Vox about women freezing
2:46
their eggs. And you noted
2:48
in this piece that women sometimes
2:51
talk about freezing their eggs as kind
2:53
of an insurance policy against time.
2:56
You know, I freeze now and then I
2:58
fertilize when it's convenient. Is
3:01
it working the way we seem to think it is working?
3:03
We now have more data than ever about
3:06
the effectiveness of egg freezing. And while it
3:09
is working for some people, and you know, some
3:11
people go and have a great experience, it
3:13
has failed to live up to some of its early
3:16
hype. I think at the beginning, you
3:18
know, it was thought this was going
3:20
to usher in this new era of
3:22
gender equality. Tech giants Facebook and Apple
3:25
confirming they will pay for female employees
3:27
to freeze their eggs, telling ABC News
3:29
we want to empower women at Apple
3:31
to do the best work of their
3:33
lives. It seemed sort
3:36
of careless of me not to take advantage of
3:38
the fact that I can't stop myself from aging.
3:40
I can't fall in love
3:43
overnight, but I am
3:45
able to stop the aging of my eggs.
3:47
It's going to free people to pursue
3:49
careers in a really different way. But
3:52
now there are a lot of concerns with
3:54
some experts saying this procedure really just serves
3:56
as another way for companies to make money
3:59
from stoking women's anxieties. What
4:02
was the promise? Like, if you could boil it
4:04
down to a few words, when women were sold
4:06
on freezing their eggs, what were they told? Around
4:09
2014, when this procedure was really becoming
4:11
more mainstream, there was a thought that
4:13
it would be as big as the
4:15
birth control pill in terms of how
4:17
much it would change people's lives. And
4:19
then there's this really famous 2014 Bloomberg
4:22
Businessweek cover story that used the phrase,
4:24
freeze your eggs, free your career. In
4:27
a world in which life isn't dictated by
4:29
a biological clock, if a 25-year-old banks
4:32
her eggs and 35 is up for
4:34
a huge promotion, she can go for
4:36
it wholeheartedly without worrying about missing out
4:38
on having a baby. So there
4:41
was this idea it's going to upend
4:43
gender roles, it's going to upend, you
4:45
know, the way that women might be
4:47
discriminated against in the workplace. Indeed,
4:49
if you look at the dominant marriage
4:51
strategy in 1980, it was for men
4:53
to delay their parenthood and then marry
4:56
and impregnate younger women. Now
4:58
in the 2010s, we actually
5:00
have a more gender equitable strategy
5:02
where both partners can invest in
5:04
themselves and delay. It's going to
5:06
change everything almost the way that birth
5:09
control changed everything in the 1940s. The
5:15
first successful births from frozen eggs were actually all
5:17
the way back in 1986, a pair
5:20
of twins born in Australia. That
5:22
turned out to be kind of difficult to replicate for
5:25
a long time. So egg freezing
5:27
doesn't really take off until the 1990s
5:29
starting at a clinic in Italy. So
5:32
the Italian government was about to pass a law
5:34
restricting the use of frozen embryos. So
5:36
that's when the egg is fertilized with sperm and starts to
5:38
grow. Restricting the use of
5:40
frozen embryos on the ground, they constituted human
5:42
life. And so freezing
5:44
the eggs instead became a way to
5:46
get around this law and still treat
5:48
patients with infertility. When
5:50
we fast forward a little bit in the
5:53
early 2000s, the procedure starts to spread more
5:55
to the United States, around the world. Probably when
5:57
this comes into its own, it will be more
5:59
liberal. to women than the
6:02
oral contraceptives were back in the 1960s.
6:05
A lot of people who were freezing
6:07
their eggs had a medical condition that
6:09
really made it necessary in some ways
6:12
to preserve fertility. So for example, people
6:14
who were about to undergo chemotherapy
6:16
for cancer, which might impact
6:19
their fertility. It starts to really get
6:21
a lot of mainstream interest in 2012
6:23
when the American Society for Reproductive Medicine
6:25
announced it should no longer be considered
6:27
experimental. It said babies born from frozen
6:29
eggs are as healthy as those from
6:31
fresh eggs, but the committee said the
6:33
procedure should be limited in its use.
6:36
In 2012, what really changed is
6:39
people started to freeze their eggs more
6:41
because they weren't in a position to have children
6:43
right then. They didn't necessarily have a medical condition,
6:46
but they hadn't met the right partner,
6:48
there were career concerns. I thought
6:50
it would be really nice if I could make
6:53
it so that I had a baby when my
6:55
life was ready instead of just because my body
6:57
is ready. So there's this big change in the
6:59
way that egg freezing was used. How
7:04
does this process actually work? The procedure starts
7:06
with 10 to 14 days of hormone injections,
7:08
often two or three per day, to kind
7:11
of stimulate the ovaries to produce more eggs
7:13
than normal. Typically, in
7:15
a cycle, the body is producing
7:18
one, maybe two eggs, but in
7:20
order to harvest eggs for egg freezing, you want the
7:22
ovaries to make a bunch more. So you're taking these
7:24
medications, you're either injecting them yourself, if
7:26
you have a partner, you can get the partner to do
7:28
it, you can get a friend to do it, but it's
7:30
needles. And then you're
7:33
typically going to a clinic two to three
7:35
times a week for ultrasounds, blood work, you're
7:37
monitoring the whole process. Finally,
7:40
when the eggs are the right size, the doctor says you're ready,
7:42
you take another injection, a
7:44
trigger shot, that's designed to complete
7:46
that maturation process. About
7:48
36 hours after that trigger shot, and this
7:50
has to be timed really well, you'll go
7:52
in, a doctor will extract
7:54
the eggs using a needle that actually
7:57
threads up through the vagina into the
7:59
ovary. And, you
8:01
know, it's not a super
8:03
risky procedure, but there's a small risk.
8:05
There can be complications. You
8:07
can experience blood clots. You can have something
8:09
called an ovarian torsion, which is as bad
8:12
as it sounds. But if everything
8:14
goes well, if you're under 38, you
8:16
might get between 10 and 20 eggs. And
8:20
then they put the eggs on liquid nitrogen.
8:22
They put them on ice. And
8:25
you basically store them away until at some point maybe
8:27
you want to use them. Okay.
8:29
So you just walked us through what it's like
8:31
to do that process one time. What
8:33
would that one time cost? It's a lot of money,
8:36
usually five figures. Wow. Between $10,000 and $15,000 a cycle,
8:38
one patient I talked to, she froze her eggs in
8:40
2022. So
8:45
pretty recently cost her about $14,000. And
8:49
that included some storage fees. Now
8:51
storage fees are going up. They
8:54
can be about $800 a year or more. So
8:56
you do that initial 10K-ish round, right? But
9:00
you're still paying in the hundreds
9:02
every year to keep those eggs and
9:04
make sure they're safe for when you might want to use
9:06
them. One of the big promises,
9:08
as you've laid out, is that freezing your
9:10
eggs allows you time to
9:13
do things at your own pace. Is
9:17
that true? How long do a
9:19
woman's eggs actually remain viable once they've
9:21
been frozen? The freezing
9:23
process has gotten better over time. But
9:27
eggs contain a lot of water. So
9:30
they're a little harder to freeze than
9:32
some other tissues in the human body,
9:35
including actually fertilized embryos. So
9:37
there's going to be some potentially that are lost when
9:39
you saw them. It's not a perfect process. It's
9:42
also the case that your
9:44
own body, you can't necessarily support a
9:46
pregnancy forever. So at a certain point,
9:49
if you're looking at after 45, things
9:51
like this, it might be harder and
9:53
harder to be pregnant. It's
9:55
less about how long the eggs Last
9:58
once, they're frozen and more.. About
10:00
how old were you when you frozen
10:02
and how good quality were they when
10:04
they were frozen and how many where
10:07
they you know if you only for.
10:09
As for. Then you
10:11
gotta hope that. One. Of
10:13
those fertilizers, it's just it's a numbers game.
10:16
Okay, so we have an expensive
10:18
process and typically things do things
10:20
like this to get cheaper overtime.
10:22
They go from being like a
10:24
super rare thing to more com
10:26
and this has become a huge
10:29
growth industry. Didn't you talk us
10:31
through the process of being very
10:33
rare to it being. Highly
10:35
available to to anybody. last five
10:38
figures. Soon. Twenty Twelve After
10:40
the American Society Reproductive Medicine says this
10:42
is no. longer, experimental. From there we.
10:44
Can I get this explosion and media
10:46
coverage? And so now we're seeing Egg
10:48
Freezing or National Medical Group decided that
10:50
freezing eggs are selling a lot of
10:52
promise and them are also seeing these
10:55
new companies spring up specifically to to
10:57
offer a market. Egg Freezing is. Kind
10:59
by the is reinventing the women's health
11:01
care experienced modern. Fertility
11:04
which has long since when he sixteen
11:06
offered Instagram influencers reduced rates in exchange
11:08
for posting about egg freezing and there
11:11
was a quote unquote Fertility Studio called
11:13
Trellis ah that open in the flat
11:15
iron in Manhattan and twenty teen called
11:17
us off the equinox of egg freezing
11:20
the sort of kind body which is
11:22
also launched and twenty a team had
11:24
like parties of drinks and scented candles.
11:27
The women invited to this party all
11:29
have something in common. they're successful in
11:31
their careers with no immediate plans to
11:33
have children's but they know their eggs
11:36
will never be as healthy as they
11:38
are now. I feel like there's a
11:40
lot of pressure to find the right
11:43
person and the clock is ticking and
11:45
you don't wanna be resting. Nine Eleven
11:47
companies would have kind of a distinctly
11:49
like millennial twenty hens ethos and is
11:52
hagglund like plan your path or it's
11:54
really about like empowerment and women's empowerment.
11:56
There was a girl boss vibe I
11:58
think to this. It's
12:02
just about hanging out and realizing that
12:04
you're not alone. There are a lot
12:06
of women out there just like you.
12:08
Who are you targeting specifically? Anyone with
12:10
a question about whether egg freezing is
12:12
for them? And we do get
12:15
this real skyrocketing popularity, so the
12:17
figure that I've seen is about 2,500 people
12:19
were freezing their eggs in 2012, and by 2020, that was 13,000.
12:35
Boxes Anna North, she'll be back along
12:37
with writer Maymay Fox, who was among
12:39
the thousands of women who were told
12:41
that freezing eggs was a way to
12:43
buy them more time. Mimi's
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always wanted to have children my entire
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life, and I love being
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around kids. I desperately want
16:44
to have my own, but I have gone through
16:46
a divorce when I was in my early 30s
16:50
that left me single at this stage of
16:52
my life. I
16:55
was ghostwriting a book for Sarah
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Brokaw, and we went into the
17:00
office of a fertility doctor, Dr.
17:03
Jamie Griffo at NYU, to
17:05
interview him about fertility issues.
17:09
And at this point, I'm 37 years old, and I'm in
17:11
excellent health. So
17:14
I'm just thinking that I'm not going to
17:16
have any trouble getting pregnant if and when
17:18
I finally meet the love of my life.
17:22
So we go into the office, and
17:24
he sits us down at a table,
17:26
and he shows us a chart. This
17:29
is a graph that illustrates
17:32
the rate of infertility of
17:35
women after the age of 35. And
17:38
it isn't a gradual
17:40
decline in fertility, as I had imagined.
17:43
It is an exponential curve.
17:45
So with each passing month
17:48
after the age of 35, your
17:50
chances of conceiving a child are
17:53
exponentially less. And I'm able
17:55
to ask Dr. Griffo, well, what about me?
17:57
I'm in perfect health. I do yoga. I
17:59
eat well. like I've never been a
18:01
smoker, like this isn't true for me, right?
18:04
And he's just like, no, that has nothing
18:06
to do with it. These eggs have been
18:08
in your body since you were born. And
18:11
this is a degradation that happens to every
18:13
woman as a result of age. I
18:18
am shocked and
18:20
devastated. And my eyes are wide. And then
18:22
we're talking to him about what are your
18:24
options. And one of
18:26
the options at this time was still
18:29
considered an experimental procedure, freezing your eggs.
18:34
I wanted to have children with a partner.
18:36
But I was single,
18:38
and I didn't have a partner. So I was
18:40
like, gosh, I better freeze my eggs. There
18:43
was starting to be a lot of
18:45
chatter in the media. And there are
18:47
people like there were women throwing egg
18:49
freezing parties. And it
18:51
was very much seen as
18:54
your insurance policy. Why
18:57
wouldn't you do this? Why wouldn't you
18:59
go get insurance? If you have
19:01
a choice, if you have, you know, it's medically you're
19:03
able to do it and financially you're able to do
19:05
it, why wouldn't you? So
19:12
I scratched up $10,000. So a lot
19:14
of money for me at the time.
19:16
And I went through the process of
19:18
freezing my eggs. And it
19:20
was very successful. I was told I
19:23
had 18 frozen eggs. It
19:25
was a terrific number
19:28
for my age. They all looked
19:30
healthy. I had really great hormone
19:32
numbers and everything looks strong. So
19:35
I had my insurance policy. That
19:38
piece of it was really important
19:40
to me that psychologically at
19:42
that point, I relaxed a
19:45
little bit about the ticking clock. And
19:47
I was able to go
19:50
back to dating with more
19:52
confidence and more calm
19:55
and more presence to just like, let's
19:58
enjoy this process. instead of being in
20:00
a blind panic about, oh my God, I
20:02
have to meet a guy so I can get married
20:04
and have kids. Shortly
20:07
thereafter, went to Costa Rica to learn
20:09
to surf and to write, and I
20:11
met the love of my life, my
20:13
husband, Kiran Ramchandran. And
20:16
it still took us a
20:18
few years to get together. We
20:21
were both involved in sort of
20:23
on-again, off-again relationships. And eventually, three
20:25
years later, I moved down to
20:28
LA, and we decided
20:30
to get married and immediately start trying to
20:32
have kids, because I was rapidly
20:34
approaching my 40th birthday, and he was
20:36
a little bit older, at 42. We
20:40
got pregnant, we were
20:42
thrilled over the moon, and
20:44
then I miscarried, which was
20:46
devastating. And at that point,
20:48
we went in to see the fertility doctor in
20:50
LA, and he said, "'Look,
20:53
why don't you use those frozen eggs?
20:55
"'This is the perfect opportunity.'" And
20:59
I thought, that's a great idea, let's do
21:01
it. So we arranged for them to be
21:03
shipped from Stanford facility
21:05
in San Francisco down to
21:08
LA. And
21:10
the morning that my eggs arrived in Los
21:12
Angeles was the worst day of my life.
21:19
I get a call from the fertility doctor,
21:22
and he says, I've bad news.
21:25
Are you sitting down? All
21:28
your eggs were destroyed in
21:31
shipping. And
21:33
as you might imagine, my
21:36
first reaction was just confusion. I
21:38
asked a million questions. Why,
21:41
what happened? He said, well, it looks
21:43
like they were misspacked. I
21:46
was like, what are you talking about? He said, do you wanna
21:48
come in and see? And I said,
21:50
absolutely. So, Ciaran and I
21:53
drove to the doctor's office in LA,
21:55
and he showed us these vials where
21:57
the tops had not been appropriate. at
22:00
least sealed, it had not been packaged. So if you
22:02
can imagine taking eggs that you
22:04
buy from the store and instead of
22:06
them being carefully packaged in cartons that
22:08
protect them during shipping, they're just kind
22:10
of all tossed into one bin together.
22:13
I was so heartbroken. I
22:16
mean, I really cried
22:18
and felt angry at the universe
22:23
and had to do a lot
22:25
of work to get past it. One
22:31
of my decisions actually was to
22:33
file a lawsuit against Stanford for
22:36
medical negligence. And
22:38
we actually did file a lawsuit and it went
22:40
to court and the judge threw it out because
22:42
he said it was an experimental procedure. No
22:46
one told me there was any risk involved
22:49
in shipping and that would have been so
22:51
easily solved. I mean, I was in LA
22:53
and I could have easily
22:56
flown up to San Francisco and
22:58
had the procedure done
23:00
entirely there if I had been told
23:02
that there was a risk in shipping, which I was
23:04
not. That
23:11
was Maymay Fox. She's a New York Times
23:14
bestselling author and editor and a contributor
23:16
to Forbes. All right, Vox's Anna
23:18
North is back with us now. So Anna
23:20
Maymay was a source in your Vox story
23:23
about egg freezing. That's how we met her.
23:25
Can you tell us how common stories
23:28
like hers really are? She's
23:30
not the only person to have encountered
23:32
problems with egg transportation or egg storage.
23:34
There was a 2022 study that found at least
23:37
nine storage tank failures over 15 years affecting
23:40
1,800 patients. And
23:42
then, you know, those are sort of the
23:45
technological problems. These are accidents, maybe things that
23:47
wouldn't be expected. But
23:49
egg freezing patients also kind of have to
23:51
contend with the fact that the human body
23:54
itself is unpredictable, even with this
23:56
new technology. So there's just
23:58
really a lot of points at which egg freezing can be. fail
24:01
and the doctor who studies this really walked me through
24:03
it. First of all, the ovaries
24:05
might not produce enough eggs. Even with the medications that
24:07
are supposed to make them do that, the
24:10
eggs might not survive the freezing process. When
24:13
they're thawed, they might not fertilize
24:15
properly. And then if
24:18
they're fertilized, those embryos might not
24:20
implant properly in the uterus. So,
24:22
you know, just like with anything around pregnancy
24:25
and fertility, there's a lot of uncertainty is
24:27
really baked into the process. Are
24:29
any of these companies able to tell you or is
24:31
any of the data able to tell you like how
24:35
frequently this happens? So is it possible to
24:38
say if you freeze your eggs about half
24:40
the time, it's not going to result in
24:42
a viable pregnancy? Do we have numbers like that?
24:45
Increasingly, we have data. There's a 2022 study
24:48
out of NYU that got a lot
24:50
of attention. They found that the chance
24:52
of a live birth from frozen eggs
24:54
overall was about 39%. Now, that
24:58
chance goes up if the
25:00
person is younger when they freeze eggs. And it
25:02
also goes up the more eggs you freeze. So
25:05
if you freeze a lot, you have a better
25:07
chance of some of them fertilizing and becoming viable.
25:10
But what the study author Sarah Cascante told me
25:12
is there isn't a guarantee of having a baby
25:14
from egg freezing. Would
25:17
you characterize it as a necessary thing to
25:19
do or who would it be necessary for?
25:21
I think it's so complicated. When I talked
25:23
to doctors, there sort of was a sweet
25:25
spot of like a person that they might
25:27
counsel to consider egg freezing. But,
25:31
you know, that person is not 22, right?
25:33
Because someone who's quite young, they have
25:36
a lot of time to build their
25:38
life in different ways. They have a lot of
25:41
time to conceive without assistance. There's
25:43
not really a need, even though there are some
25:45
companies that have marketed to very young people about
25:47
this. There's not really a need, a
25:49
lot of experts told me, for someone who's quite
25:52
young to go through this whole process that costs
25:54
thousands of dollars, that involves giving yourself shots, that
25:56
involves some risk of getting sick, you know, for
25:58
something that they're probably not going to eat. use.
26:01
Even for people who freeze their eggs, they're
26:03
not typically going back and using them.
26:05
Only about 12% of patients worldwide actually
26:08
go back to use those frozen eggs.
26:11
So a lot of times they're
26:13
conceiving without assistance or they're
26:15
deciding not to become parents or maybe
26:17
they're becoming parents through adoption or they're
26:20
becoming parents through partnering with someone who
26:22
has children of their own. You know,
26:24
it's, it's something that I do
26:26
think a lot of people like to have and
26:28
people who freeze their eggs typically report kind of
26:30
a feeling of empowerment and a feeling like
26:32
their stress levels went down. They did something
26:34
for themselves, but it's actually not something
26:36
that people are using biologically for
26:39
the most part to build their families.
26:45
All of that was really a dark,
26:47
dark period in my life. I will
26:49
say that the good news is we
26:51
went on to do
26:53
several rounds of IVF and on
26:55
the third round we were successful
26:58
and not only that, but we tried
27:01
for twins and we succeeded and
27:03
I now have beautiful, healthy twin
27:05
boys. So the story has a
27:08
happy ending, but it
27:10
was definitely not what I expected. That
27:27
was Mae Mae Fox. We're all very happy for
27:29
her. And you also heard from Vox senior
27:31
correspondent Anna North. Victoria Chamberlain produced
27:33
today's show and Amina El-Sadi
27:35
edited Patrick Boyd engineered facts
27:38
by Laura Bullard. Amna-Well King,
27:40
it's today explained. you
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