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High Intensity Health Radio with Mike Mutzel, MS

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#166: Anat Baniel- How Movement Changes the Brain, Learning & Neuroplasticity
Einstein once said, “Nothing happens until something moves." 
 Movement is an essential element to both life and brain health.  
 Without it, life is unthinkable says human neuroplasticity expert, Anat Baniel.  
 She's written many books on the topic and helps people reshape their brain, through movement.  Check out the show notes: http://highintensityhealth.com/166  
 In this video, Anat shares some new ways to help both the very young and old learn new skills (and preserve brain function with age).   In this interview she discusses:   -Why variability, not repetition, accelerates learning -How movement with attention creates new connections in the brain -Practical tips to drive positive brain changes and induce neuroplasticity -Why clapping and rewarding children’s behavior may slow learning  Check out the show notes: http://highintensityhealth.com/166 Support the podcast: http://theautismintensive.com
Nerd Alert #1 Autophagy & Fasting Deep Dive
There’s a lot of speculation about when autophagy starts and stops. In today’s show we’ll cover the details. This show is brought to you by MYOXCIENCE Nutrition, tools to help optimize sleep and support blood sugar health. Save on your next order using coupon code HIH at checkout bit.ly/myoxcience About Today's Show: “Fast for 18 hours and autophagy kicks-in,” the guru says. The truth is, autophagy is occurring at different rates in different tissues for different people. In this show, we’ll add some clarity to this topic that’ll help you figure out how long and frequently you should fast to enhance autophagy. -Insights from human fasting studies about autophagy and fast duration -Herbs and foods that may enhance autophagy Link to show notes and research: https://highintensityhealth.com Related Podcast with Peter Attia, MD: http://bit.ly/2QWLAAY Autophagy and Time-Restricted Feeding: https://www.instagram.com/p/Bya8oWNJNpF/  
#127: Maya Shetreat-Klein, MD - The Dirt Cure, how food is changing kids’ bodies and brains
Pediatric neurologist best-selling author of The Dirt Cure exposes new science about how gut microbes affect mood. It turns out that our immune system influences mood and behavior in the brain, and gut microbes directly influence our immune system. And as you know, many things affect gut microbes (antibiotics, birthing method, foods and even stress.) She shares case histories about how antibiotics may cause ADHD, and well, how eating dirt and color rich foods may help calm the mind.  “Our brain is not sitting on top of the totem pole isolated from the rest of the body,” says Dr. Shetreat-Klein. Here are some highlights 07:30 Digestive Tract/Immune System and the Brain 15:20 Gut Bacterial Diversity is the Key to Balancing the Immune System: 18:39 How Can We Ensure a Variety of Microbes? 27:24 ADD/ADHD Treatment Alternatives 35:51 The Importance of Phytonutrients
#125: Derrick MacFabe, MD- Carbohydrates, Ketones, Gut Microbes and Brain Function
Dr. MacFabe has extensively studied how gut bacterial-deprived short chain fatty acids (SCFA) affect behavior and neurology. In brief, when we eat, we don’t just feed ourselves, we feed these little guys in our gut, largely anaerobic. They ferment.  They eat and depends what they eat. They eat these certain foods. We were interested in mostly these refined high sugar carbohydrates, some wheat-based carbs. You feed these bacteria. They ferment, kind of like giving carbs to yeast to make beer and alcohol, they make compounds very similar to alcohol called short chain fatty acids. Some of us know from personal experience, what small molecules like alcohol can do very complex things with your brain and your behavior, again, not all good and not all bad, but also very sensitive early in development. We had this idea, could these bacteria, which we did know these bacteria produced compounds called short chain fatty acids, kind of like alcohol, and could these compounds, have an effect on us similar to the intoxication of alcohol. In this episode, we take a deep dive into how SCFA affect behavior, immune function and metabolism.
#116: John Principe, MD, Physician Quits Medicine to Become a Cook
After 25 years of practicing internal medicine, Dr. Principe got frustrated that his patients were still sick (and some were dying). So he closed his business, went to culinary school and re-opened a new clinic focused around teaching people how to better manage stress and cook real food!  His story is so unique, we had to film this onsite in his “teaching kitchen” adjacent to his medical clinic in Chicago, IL. His clinic is called WellBeingMD and is located in the Chicago suburbs.
#112: Robynne Chutkan, MD- Gastroenterologist Says Live Dirty, Eat Clean
  Dr Chutkan is a member of the faculty at Georgetown Hospital since 1997, Dr Chutkan founded the Digestive Center for Women (DCW) in 2004, an integrative gastroenterology practice that includes nutritional therapy, stress reducing techniques such as meditation, biofeedback and counseling, as well as gastrointestinal procedures like endoscopy, colonoscopy, and video capsule endoscopy. In addition to digestive disorders in women, her clinical areas of interest include alterations in gut bacteria (dysbiosis), inflammatory bowel diseases, irritable bowel syndrome, and food as medicine. She is a recognized leader in gastroenterology both nationally and internationally and Washingtonian magazine has consistently named her one of the top doctors in her field. Board certified in Gastroenterology, Dr Chutkan serves on numerous committees and boards and is actively involved in patient and physician education. She is a past Governing Board member of the American Society for Gastrointestinal Endoscopy (ASGE) and former Chair of their Training Committee and Public Relations Committee. She is the author of the bestselling book Gutbliss, and the newly released The Microbiome Solution, and has lectured extensively throughout the United States and Europe.    Here are a few highlights from the show:   22:55 The Over-Prescribing of Antibiotics: In her new book, The Microbiome Solution, Dr. Chutkan has a list of 10 questions to ask your doctor if you are about to be prescribed an antibiotic. She also provides a list of 10 things to do if you must take antibiotics.   31:51 Good News—You Can Change Your Gut Microbes: Many of our cravings are mediated by gut bacteria. In numerous ways, our gut microbes drive this behavior. Different strains of gut bacteria will overthrow others and dominate.   35:28 The Mysteries of Morning Breath: Because we sleep with our mouths closed, cutting off much of the oxygen, the bacteria in our mouths shift and give us morning breath.     41:23 Fecal Matter Transplantation—Is It Right for You? About 50% of the stool is bacteria, but there are toxins, viruses, and other things in your stool that your body is eliminating.
#147: Stephanie Seneff, PhD- Belly Fat, GMO Foods, Glyphosate and Autism
Scientist Says Body Fat Is Actually Protective? About a year ago, I sat down with MIT researcher Dr. Stephanie Seneff to talk about glyphosate and autism. Our discussion motivated me to start growing my own vegetables. Even organic food contains significant levels of this herbicide that has been linked to many health ailments. Recent research shows that this substance has made it into our water supplies and rainwater. Dr. Seneff also brought up an interesting finding: the autism epidemic parallels the increase in the consumption of Roundup Ready crops. We often hear scientists blame sugar consumption and low-fat diets for the increasing epidemic, but Stephanie Seneff’s research suggests that environmental toxins and glyphosate are hidden drivers of the obesity and autism epidemic. otherwise. She says that body fat is protective against environmental toxins, and this is why: Here are a few key takeaways from the interview: This discussion is part of the autism intensive interview series that we aired in January. If you’re interested in checking out some of those interviews and learning more about how to raise happy and healthy children, click here. 02:18 Glyphosate on Crops 03:05 Human Consumption of Glyphosate 04:35 History of Glyphosate 05:50 Glyphosate/Disease Correlations 06:38 Tracking Potential Causes of Autism, Obesity 09:21 Gut Microbes and Glyphosate 10:13 New Glyphosate Product: 13:31 Oxalic Acid and Kidney Function 15:51 Preventing Glyphosate Exposure 19:32 Diseases Linked to Glyphosate Exposure 20:13 Bone Health and Glyphosate 22:01 Obesity, Toxins and Glyphosate 28:32 Glyphosate and the Gut Microbiome 30:34 Confined Animal Feeding Operations and Antibiotics 32:11 Glyposate and Gut Permeability (Leaky Gut) 36:24 Glyphosate and Methylation (MTHFR) 38:15 Folic Acid, Folate and GMO Foods 49:48 Estrogen Disruption and Glyphosate
#135: Brian Mowll, DC- Balancing and Testing Blood Sugar
A new study in a reputable medical journal reported that 50% of the adult population has diabetes or prediabetes.   But here’s the real cold water: folks with elevated glucose have a much higher risk of developing blindness, getting their legs ampuation and, worst of all, brain atrophy and dementia.   (Alzheimer’s is now dubbed diabetes of the brain.)    These scary facts motivated diabetes educator, Brian Mowll to host the 3rd annual Diabetes Summit.   Check it out: highintensityhealth.com/diabetes Dr. Brian and I discussed key nutrients to balance gut hormones and bacteria which can have a huge effect on blood sugar regulation.)  But that’s not all… Dr. Brian and I recorded a special interview below to discuss a range of topics that can help you balance your blood sugar control right now. This was by far one of the most practical discussions on getting control over blood sugar that I’ve heard in a long time. Key Takeaways from Dr. Mowll’s Chat: 05:06 Assessing our Blood Sugar: Why should all have a glucometer and be testing our blood sugar! 09:38 Blood Sugar Thresholds: What are safe post meal blood sugar levels? 16:23 Type 2 Diabetes Subtype: Not all diabetes is the same 23:56 Hemoglobin A1C Biomarker: What’s optimal VS what’s “normal” 22:44 Triglyceride Biomarker: Why this measures metabolic flexibility 48:43 Berberine and Blood Sugar: New science P.S. When you sign up for the Diabetes Summit, forward me your registration and I’ll give you access to my 60 minute Circadian Rhythm Master Class video.
#143: Trudy Scott, CN- Anxiety Relief Techniques: Food and Supplements
Anti-anxiety expert, Trudy Scott, CN shared the recent science about food and mood. If you or someone you know often feels agitated, irritable or anxious, be sure to watch to check this out! Trudy also discussed the details of a study finding a strong link between grass fed red meat consumption and good mental health in women. Here’s a few key takeaways: 05:12 What is a Panic Attack? (what to do if you have one) 09:25 Low Serotonin 16:41 Food Sources of Tryptophan 19:23 Low GABA (what do you do?) 26:55 Copper/Zinc Balance 35:52 Oxytocin  
#254 Bonus: Intermittent Fasting VS Calorie Restriction- A review of the Research
Hi there, Welcome back! This is the audio synthesis of two recent popular YouTube videos discussing the nutritional ketosis on the cellular level plus the metabolic difference between intermittent fasting (IF) and prolonged calorie restriction (also know as continuous energy deficit). We break down a recent study by researchers at University of Colorado medical school. ➢ This show is brought to you by MYOXCIENCE Nutrition formulas, high quality supplements to help you optimize your physical performance while keeping health top of find. https://myoxcience.com 
Use coupon code: HIH to save 20% OFF your first order Link to Show Notes: https://highintensityhealth.com/254-bonus
#252: The Perfect Body May Not Bring Happiness w/ Victoria Field
This episode is brought to you by: ➢ Perfect Keto, the makers of high-quality exogenous ketones and MCT oil products.*Save over 20% OFF: https://www.perfectketo.com/HIH ** Use promo code HIH20 About Today’s Show https://highintensityhealth.com/252 Former IFBB Pro Figure Competitor, discusses all the mental health benefits linked to lifting weights and how being ultra-ripped may not bring happiness. She’s a ketogenic diet educator and is organizing educational events to help others understand how the ketogenic diet can optimize their metabolism and quality of life. Check out the: https://metabolichealthsummit.com Check out the show notes and resources for this show: https://highintensityhealth.com/252
#241: Coffee Enemas, Constipation & Colonics w/ Marisol Teijeiro, ND
Marisol Teijeiro, ND specializes in helping her patients overcome constipation and improve gut health with coffee enemas and colon hydrotherapy and naturopathic detoxification strategies. Here's a link to the show notes and video interview: https://highintensityhealth.com/241 This show is brought to you by MYOXCIENCE Nutrition formulas, high quality supplements to help you optimize your physical performance while keeping health top of find. Use coupon code: HIH to save 20% OFF your first order Here’s some key takeaways from today's show:    05:04 Colonic is the best tool to help heal the gut. It is the equivalent to 20 enemas. 06:35 Pouches in your large intestine may not get flushed with your bowel movements, causing reinfection and re-pollution into your body. 08:30 The liver and the gallbladder are stimulated to dump toxins with a colonic. 09:01 A healthy gut should have a 24 hour transit time. 10:25 Taking probiotics with an unhealthy gut is tantamount to putting paint over wallpaper. You have to remove the wallpaper. 10:52 Many of us can resolve many conditions within 4 to 6 weeks, with colonic hydrotherapy. 11:36 A colonic cleanse series should be done twice a year. 14:51 We are all exposed to chemicals/toxins and should do cleanses. 15:59 Washing can remove as much as 70% of the chemicals from your fruits and vegetables, even organic, which can be exposed to chemicals in handling. 17:22 Pooping properly starts with eating lots of vegetables, drinking lots of clean water, and drinking green tea. 18:34 Castor oil is a healing anointing oil. 19:10 Dr. Teijeiro uses Queen of Thrones Castor Oil and castor oil packs, which she created. 20:48 Castor oil reduces biofilm. 21:39 The molecular structure of castor oil is similar to prostaglandin E3, a natural anti-inflammatory molecule within our bodies. 22:15 Where you place a castor oil pack on your body stimulates the organs inside. 26:52 Beets are full of glycine, an amino acid that helps the liver detoxify. They also help to get your bowels moving. 27:32 Arugula’s bitterness stimulates the liver. Green tea can get your body cleaning in many different ways. 28:40 Fat with your coffee will reduce sugar throughout your system, but it will increase the amount of sugar in your gut, impacting candida and gut health. 30:00 Colonics can cost from $90 to $150. 30:56 If you cannot afford colonics, do regular water enemas, use castor oil packs and do magnesium flushes. 32:07 Dr. Teijeiro’s book, Oh, Shit comes out in the fall. Here's a link to the show notes and video interview: https://highintensityhealth.com/241
#257: Conquering Limiting Beliefs & The Mental Side of Fat Loss w/ Drew Manning
Drew's the author of the NYT Bestselling book, Fit 2 Fat 2 Fit and Complete Keto. ➢ This episode is brought to you by ButcherBox.com  
 Serving the High Intensity Health community with truly 100% grass-fed, pasture raised beef, chicken and pork. 
Get $20 off your order and two pounds of free wild-caught alaskan salmon! https://www.butcherbox.com/hih-2 About this Show: Drew gained over 75 pounds of fat in six months and lost it all six months later. His weight gain and loss experiment helped him better understand the emotional struggles we all face when we strive to improve our health with diet and lifestyle change. We explore ways to overcome emotional eating and limiting beliefs. Link to today’s show notes and key takeaways: https://highintensityhealth.com/257
#91: Eric Balcavage, DC- Methylation, Histamine and Nutrient-Gene Interactions
We all have subtle abnormalities in a key cellular process called methylation. Without proper methylation, we can’t properly detoxify, make hormones, neurotransmitters, creatine and glutathione. Dr. Eric explains the critical ways to support methylation, starting with the basic foundational principles in functional medicine.
#160: Alessandro Ferretti- Time-Restricted Eating, Sleep and Ketosis
Welcome to episode #160 with Alessandro Ferretti, Dip ION, mBANT. Alessandro is a leading nutritionist in the UK and shared his latest findings in the realm of time-restricted feeding, ketogenic diet applications and using nutrients to rebalance circadian rhythms. This interview is jam-packed with nuggets; so be sure to get and pen and paper out. Watch the full interview and check out the show notes page: http://highintensityhealth.com/time-restricted-feeding View related interviews on YouTube: https://youtu.be/MQpsFTVAqpA?list=PL0ovt_TbvVmYvrI48Tzs1vhe4o2eUn8qU NOTE: Our usual videographer, Sam couldn't be live in San Diego for this one, so we had a substitute...and thus the audio quality is not what you may be used to. I sincerely apologize for this, and hope you can still catch some of the many takeaways. Here are some key takeaways: 02:04Time Restricted Feeding: There are different styles. Some of us use stimulants with fats. The best results come from abstaining from ingesting anything of caloric value during fasting. It instigates different glucose regulations and ketone readings. There is also alternate day fasting (a full 24 hrs). The more fat adapted you become and the more regular your ketones in both breath and blood, the stronger the correlation to a sustained increased HRV (heartrate variability), 05:10 Secondary Benefits of Ketones: Ketones are signaling molecules, not just substitutions for macronutrients or energy substrates. Ketones effect metabolic and inflammatory signatures, contributing to an increase in HRV. Beta-hydroxybutyrate and acetyl acetate promotes epigenetic control, mitochondrial protection, and histone acetylation function, reducing free radical damage to mitochondria. 07:16 Inflammation and Exercise: 13:17 Glycogen Storage and Keto Adaptation: The benefits of being a fat adapted person will stay, even when glycogen stores are tapped. 16:36 Inflammatory Proteins and Postworkout Recovery: Casein is often recommended at certain amounts at certain times of the day. Inflammatory proteins, post workout, stimulate more inflammation to shorten the time it takes to create new tissue. 17:11 Post Workout Nutrition and Glycogen Replenishment: We have been taught that we need protein and carbs to spike glycogen replenishment and spike insulin. The body can make glucose and store it as glycogen from virtually every substrate. Through gluconeogenesis from glycerol, fats or protein for the amino acids that are able to be converted to glucose can rebuild the stores. 19:58 Post Workout Fasting: The longer you fast post training, the recovery period is slightly shorter and secretions are made of human growth hormone and testosterone increase healing and shorten total recovery time. This breaks with what we have been taught. 23:25 How Ketosis Enhances our Metabolic Efficiency: Fat adapted people use less heat (thermogenesis) and you produce more ATP, given the same number of carbons you have. On top of that, fat is a cleaner and slow burning fuel. 28:35 Advice for Competitive Athletes and Cross Fitters: To become truly fat adapted, where your body preferentially uses fats to supply energy on demand, depending upon how much oxygen you have available through intensity, can take 3 to 9 months. 38:25 Going In and Out of Ketosis: When learning to be fat adapted, different foods can push the body into alert mode and out of ketosis. 40:22 Lifestyle Shift: Becoming fat adapted is total commitment. We socialize in the evening, when intermittent fasting is best. People can be highly motivated for the therapeutic effects, like positive effects upon epilepsy. 44:28 Where to Start: A good place to start is with a high fat/low carb diet. Begin to experiment. Perhaps try an intermittent fast. Check breath acetone. 44:33 Sleep Quality: Our guts are highly active in the middle part of the day (10 a.m. to 4 p.m), thus it is logical to consume most of our calories then. Food has a substantial impact upon body rhythm. Alessandro travels extensively, but does not suffer from jet lag. He regulates this with food. His body knows that when he eats, part of the day, whatever is left, must be either evening or morning. 51:48 Food and Circadian Rhythm: We discuss how foods can be used to restore (AKA entrain circadian rhythms)   Watch the full interview and check out the full show notes page: http://highintensityhealth.com/time-restricted-feeding
#172: Cate Shanahan, MD- Traditional Diets and Fat Adapted Athletes
Dr. Cate Shanahan is a board certified Family Physician, author of Deep Nutrition and nutritional consults for the LA Lakers. In this interview, we discuss the science behind real food-based, low-carb diets and sports performance. Additionally, we discuss the Four Pillars (common findings) of all healthy human diets. ➢ Read the Show Notes: http://highintensityhealth.com/172 ➢ Deep Nutrition Book: http://amzn.to/2jj4cwT ➢Watch the video interview: https://youtu.be/FZBXb_nWG3w?list=PL0ovt_TbvVmYvrI48Tzs1vhe4o2eUn8qU
#177: Mark Burhenne, DDS- Tips to Boost Sleep Quality and Stop Mouth Breathing
Dr. Burhenne is a sleep medicine dentist and bestselling author of The 8-Hour Sleep Paradox. He discusses the importance of nose breathing for proper airway development and how to improve Watch this mouth taping tutorial and check out the snow notes: http://highintensityhealth.com/177 Key Timestamps 02:49 Mouth Breathing: 03:44 Stomach Acid: 04:30 Nose Breathing during Exercise: 07:14 Mouth Breathing during Sleep: 08:30 Bernoulli Effect: 09:25 Get Checked Out: 10:20 Narrow Airway Trend: 12:29 Reversing Structural Changes: 13:24 Impacts of Not Breathing Properly: 15:03 Benefits of Mouth Taping: 16:18 Sleep Apnea: 17:38 Children: 26:11 Mouth Taping with Sleep Apnea: 28:14 Mouth Taping with a Cold or Allergies: 30:13 Dr. Burhenne’s New Book: 32:30 Quality and Quantity Sleep Improvements: 34:18 Benefits of REM Sleep: 36:15 Kombucha: 19:04 Cavities and Staining: 44:20 Xylitol: 49:35 How to Mouth Tape:
#184: Amanda Milliquet, ND: Muscle, Mindset and Exercise on Ketogenic (Low-Carb) Diets
Weight lifting and crossfit may conjure up images of grunting and big muscles. That’s because we don’t often think about the longevity and anti-aging properties associated with weight lifting … Or how weight lifting can increase psychological resilience and transform the timid into the confident. Watch the interview and read the full show notes: http://highintensityhealth.com/184 Save Your Seat on Our Next Webinar: http://highintensityhealth.com/keto-lean-webinar And when it comes to long-term fat loss, weight lifting is possibly the most effective modality one can embrace. Sought-after naturopathic doctor and avid strength athlete Dr. Amanda Milliquet discusses all this and more. She shares the science of muscles and movement and tells a few transformation stories about how barbells shifted the once-shy into strong beings—in and out of the gym. You might like these key takeaways: 11:22 Strengthening the rhomboids: Stretching the major and the minor pectoral muscles is the first step 14:43 Sleeping: Turn off your screens at least one hour before bed 18:00 Foam rolling: Dr. Milliquet finds foam rolling to be very valuable. Cushy rollers are not helpful—if you’re not in pain, you’re not doing much. 19:06 Decreasing inflammation: Taking fish oil supplements and eating a healthy diet help fight inflammation. Happiness is a huge part of health. 21:20 Crossfit carry-over 25:02 Fat loss: If you want to lose weight, you need to lift heavy weights 28:36 Deadlifts: Use your hamstrings for deadlifts. Romanian deadlifts are good. For engaging the glutes, the Russian kettlebell swing is best. 37:05 Muscle-building tips for women: Push yourself to the limit. Create muscle fiber damage, so it comes back stronger. Make sure that you are eating enough protein. 38:46 Dr. Milliquet’s favorite nutrient: German chamomile (Matricaria chamomilla) is her favorite herb. It’s a calming tea. 39:48 Dr. Milliquet’s morning routine 45:15 Dr. Milliquet’s elevator pitch Watch the interview and read the full show notes: http://highintensityhealth.com/184  
#174: Angela Poff, PhD: Cancer as a Metabolic Disease
Cancer is classically relegated to a “disease of the immune system,” but new research suggests that “metabolic imbalances are upstream of many imbalances characteristic of cancer.” A researcher in the field, Angela Poff, PhD, discusses more. She explains how common metabolic imbalances favor cancer cell growth.  Read the show notes: http://highintensityhealth.com/174 Watch on YouTube: https://youtu.be/uKsoKtkvChA?list=PL0ovt_TbvVmYvrI48Tzs1vhe4o2eUn8qU Here are a few points we discuss in more depth: - Widespread mitochondrial dysfunction in cancer - How lactate increases the invasive capacity of the tumor and the ability to metastasize - The role of oxygen and hypoxia in cancer cell growth    
#182: Evan Hirsch, MD- Fixing Your Fatigue & Persistent Low Energy
Evan Hirsch, MD ABOIM is the author of Fix Your Fatigue. He treats a lot of patients with persistent fatigue, low energy and chronic infections. Check out this new book: http://amzn.to/2nBYeIF Check out the show notes and full video: http://highintensityhealth.com/182 Here are a few key takeaways: 02:19 First Steps: 05:09 Viruses: 09:37 Treating Co-Infections: 11:00 Changing the Terrain: 13:46 Endocrine System: 16:03 Reversing Thyroid Disease:   18:18 Contracting Bartonella: 23:51 Adrenal Support during Treatment: 24:56 Smilax: It is a blood cleanser. 25:57 Herxheimer Effect/Die off Help: 28:06 Dr. Hirsch’s Fatigue: 32:09 Sleep: 33:55 Antimicrobials: 36:54 Ketogenic/Low Carb – High Fat Diets: 37:41 Lyme and Lyme Co-Infections: 43:03 Mold: 45:27 Treating Mold: 47:49 EMF’s: 50:27 Baby Steps: 51:25 Dr. Hirsch’s Morning Routine: 54:16 Dr. Hirsch’s Favorite Nutrient: 55:34 Dr. Hirsch’s Elevator Pitch:   http://highintensityhealth.com/182
#181: Amy Berger, MS, CNS- Insulin Resistance In the Brain, Alzheimer’s and Memory Loss
A new theory is emerging in the world of cognitive decline: Alzheimer’s disease and dementia manifest from basic metabolic imbalances within the brain. The theory goes that the buildup of plaque deposits of the β-amyloid peptides in the Alzheimer’s brain may be due to too much insulin. This is because the enzyme that degrades the plaque could be too busy breaking down insulin—allowing for β-amyloid to build up. This may be why MCT oil (and the ketogenic diet) improves cognitive function in Alzheimer’s patients. Expert in the field and author of The Alzheimer's Antidote, Amy Berger, MS, CNS, explains more.  Read the show notes: http://highintensityhealth.com/181 She discusses more about: 02:16 The Alzheimer’s Brain: In a significant variant of Alzheimer’s, neurons in a certain region in the brain lose the ability to use glucose efficiently as a fuel. 03:54 Brain Fuel Metabolic Disorder: There may be a problem getting glucose into the brain or glucose in the brain into the cells to be used properly. 05:04 Type 3 Diabetes: Alzheimer’s has similarities to type 2 diabetes. There is still debate about what causes type 2 diabetes. 06:21 Diabetes and Alzheimer’s: 07:35 Early Detection: Even people in their 30s and 40s can show a decline in cerebral glucose uptake. 09:31 Ketogenic Diet to Restore Cellular Energy: 14:10 Beta Amyloid and Alzheimer’s: 16:24 Insulin Degrading Enzyme: It is an enzyme that gets rid of insulin once it has been used. It also gets rid of amyloid proteins. The Alzheimer’s brain does not appear to produce more of these amyloid proteins. 20:57 Sleep Dysregulation: People with Alzheimer’s disease tend to have sleep issues and altered circadian rhythms. 23:48 Brain’s Need for Glucose: The brain’s requirement for glucose does not imply a need for dietary carbohydrate. We can make glucose from other things. 31:25 Exogenous Ketones: With the cellular energy crisis in the brain, neurons atrophy. Axons atrophy and recede back into the neuron, breaking down cellular communication. The cells are not dead. We know this because when people receive exogenous ketones improve cognition. If you are doing a ketogenic-type diet for general health and fitness, exogenous ketones are not necessary. For neurodegeneration, exogenous ketones can be powerful. It is a short term symptom fix, unless coupled with a ketogenic or low carb diet. The ketogenic diet, which promotes your body to produce its own ketones, and other lifestyle interventions can, to some degree, reverse the damage. High glucose and high ketones in the body at the same time is type 1 diabetic ketoacidosis. 41:36 Lifestyle Changes: 47:40 ApoE4 Gene: 50:29 Statin Contribution to Alzheimer’s: 55:08 Amy’s Morning Routine: 56:58 Amy’s Favorite Exercise: 01:00:01 Amy’s Favorite Nutrient: 01:01:03 Amy’s Elevator Speech:   Read the show notes: http://highintensityhealth.com/181
#101: Jimmy Moore- High Fat Diets, Ketones and Gut Microbes
  Jimmy More is a the best selling author of Cholesterol Clarity and Keto Clarity. He maintains a popular blog and has Interviewed over 900 experts on his Livin’ La Vida Low Carb. In this podcast, Jimmy shares tips about ramping up the keto-adaptation period, myths about high-fat diets and interactions between ketogenic diets and gut bacteria. 
#94: Gerard Mullin, MD – How Gut Bacteria Thrive on Real Food, Vegetables, and Color
  Gastroenterologist, nutritionist, and top authority on the gut microbiome, Dr. Gerry Mullin shares his cutting-edge approach to rebalancing metabolism by reducing the fat-forming bacteria in the gut and reseeding it with fat-burning bacteria. In this episode, learn his top foods to eat and which to avoid. 
#163: David Perlmutter, MD – Gut Bacteria, Carbs, Fat and the Ketogenic Diet
Dr. Perlmutter came on the podcast to discuss gut bacteria, low-carb, high-fat diets, exercise and a decent view of the presidential election.  Read the full show notes page: http://bit.ly/2fDQfE2 Watch on YouTube: https://www.youtube.com/watch?v=2hR9sD9eX-A Hello there,  The presidential election is finally behind us. Hopefully the bickering and negative ads will go with it. It was a great relief to have Dr. Perlmutter come on the podcast to teach ways to balance gut bacteria with real food. He also shared tips on how to optimize brain and blood sugar health with high-fat diets and exercise. And although the topic of the election did come up, it was in the context of being mindful and grateful. Watch to learn more. I hope you’ll thoroughly enjoy this informative conversation. Be sure to grab a pen and paper as he and I took a deep dive into some key points regarding the gut microbiome and ketogenic diets. Here are some key takeaways: 03:44 The Real Problem with Carbs 05:29 Eating for Your Microbiome 07:44 Why Fat Gets Blamed 09:00 Gut Bacteria Diversity and FMT (Fecal Microbiota Transplantation) 13:30 Problems with High Fat in the Research 21:46 Gut Bacteria and Heart Disease 26:53 The Ketogenic Diet, Cancer and Brain Health   Read the full show notes page: http://bit.ly/2fDQfE2

#168: Yaron Hadad, PhD- Continuous Glucose Monitoring, Sleep and Bio-Individuality
Yaron is a mathematician and a physicist, and the chief scientist and a cofounder of Nutrino. He’s worked in a number of scientific areas, primarily in general relativity, integrable systems, partial differential equations, and the foundations of quantum theory. Yaron’s current work and research in Nutrino is a brave attempt to form a new interdisciplinary field he likes to call "mathematical nutrition."
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Podcast Details
May 8th, 2015
Latest Episode
Oct 9th, 2019
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